dihydrodaidzein

isoflavanone, 4',7-dihydroxy-

CAS: 17238-05-0 C15 H12 O4 MW: 256.25744000

Identification

Namedihydrodaidzein
CAS Number17238-05-0
FDA UNIISearch
Molecular FormulaC15 H12 O4
Molecular Weight256.25744000
MDL NumberMFCD00210494
Nikkaji NumberJ668.309F

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 873.5 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for dihydrodaidzein usage levels up tonot for fragrance use.
Recommendation for dihydrodaidzein flavor usage levels up tonot for flavor use.

BOC Sciences

Best of Chemicals Supplier

Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...

View All Website 1-631-485-4226 account@bocsci.com

TCI AMERICA

Moving Your Chemistry Forward

We continuously strive to advance our technology.

View All Website 1-800-423-8616 Sales-US@TCIchemicals.com;

Potential Uses

None Found

Natural Occurrence

found in nature

Synonyms

iso flavanone, 4',7-dihydroxy- 7- hydroxy-3-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one PubMed: Transport mechanisms for soy isoflavones and microbial metabolites dihydrogenistein and dihydrodaidzein across monolayers and membranes. PubMed: Identification of a novel dihydrodaidzein racemase essential for biosynthesis of equol from daidzein in Lactococcus sp. strain 20-92. PubMed: Production of dihydrodaidzein and dihydrogenistein by a novel oxygen-tolerant bovine rumen bacterium in the presence of atmospheric oxygen. PubMed: Dihydrodaidzein-producing Clostridium-like intestinal bacterium, strain TM-40, affects in vitro metabolism of daidzein by fecal microbiota of human male equol producer and non-producers. PubMed: R(-)-O-desmethylangolensin is the main enantiomeric form of daidzein metabolite produced by human in vitro and in vivo. PubMed: Stereospecific biotransformation of dihydrodaidzein into (3S)-equol by the human intestinal bacterium Eggerthella strain Julong 732. PubMed: [Separation of racemic flavonoids by high performance liquid chromatography using chiral mobile phase additive]. PubMed: Enantioselective synthesis of S-equol from dihydrodaidzein by a newly isolated anaerobic human intestinal bacterium. PubMed: Stereochemical determination of O-desmethylangolensin produced from daidzein. PubMed: Urinary isoflavonoids and risk of type 2 diabetes: a prospective investigation in US women. PubMed: Identification and expression of genes involved in the conversion of daidzein and genistein by the equol-forming bacterium Slackia isoflavoniconvertens. PubMed: Enhanced biosynthesis of dihydrodaidzein and dihydrogenistein by a newly isolated bovine rumen anaerobic bacterium. PubMed: Relationships among fecal daidzein metabolites, dietary habit and BMI in healthy volunteers: a preliminary study. PubMed: Identification of isoflavone metabolites dihydrodaidzein, dihydrogenistein, 6'-OH-O-dma, and cis-4-OH-equol in human urine by gas chromatography-mass spectroscopy using authentic reference compounds. PubMed: Isoflavone Pharmacokinetics and Metabolism after Consumption of a Standardized Soy and Soy-Almond Bread in Men with Asymptomatic Prostate Cancer. PubMed: Effects of an equol-producing bacterium isolated from human feces on isoflavone and lignan metabolism in mice. PubMed: Soy isoflavone metabolism in cats compared with other species: urinary metabolite concentrations and glucuronidation by liver microsomes. PubMed: Red clover isoflavone metabolite bioavailability is decreased after fructooligosaccharide supplementation. PubMed: Chiroptical study and absolute configuration of (-)-O-DMA produced from daidzein metabolism. PubMed: Identification of an enzyme system for daidzein-to-equol conversion in Slackia sp. strain NATTS. PubMed: Lactulose promotes equol production and changes the microbial community during in vitro fermentation of daidzein by fecal inocula of sows. PubMed: Feeding soybean meal increases the blood level of isoflavones and reduces the steroidogenic capacity in bovine corpora lutea, without affecting peripheral progesterone concentrations. PubMed: Cloning and expression of a novel NADP(H)-dependent daidzein reductase, an enzyme involved in the metabolism of daidzein, from equol-producing Lactococcus strain 20-92. PubMed: Analysis of tyrosinase binders from Glycyrrhiza uralensis root: evaluation and comparison of tyrosinase immobilized magnetic fishing-HPLC and reverse ultrafiltration-HPLC. PubMed: Correlations of urinary phytoestrogen excretion with lifestyle factors and dietary intakes among middle-aged and elderly Chinese women. PubMed: Isoflavone metabolism in domestic cats (Felis catus): comparison of plasma metabolites detected after ingestion of two different dietary forms of genistein and daidzein. PubMed: Identification of two novel reductases involved in equol biosynthesis in Lactococcus strain 20-92. PubMed: Urinary isoflavonoids and risk of coronary heart disease. PubMed: [Biotransformation of daidzein by resting cell system of bacterial strain isolated from bovine rumen gastric juice]. PubMed: [C-ring cleavage of liquiritigenin extracted from licorice roots by an oxygen-tolerant bovine rumen bacterium strain Aeroto-Niu-O16]. PubMed: Effects of rice bran oil on the intestinal microbiota and metabolism of isoflavones in adult mice. PubMed: Dietary isoflavone absorption, excretion, and metabolism in captive cheetahs (Acinonyx jubatus). PubMed: Isolation of an isoflavone-metabolizing, Clostridium-like bacterium, strain TM-40, from human faeces. PubMed: Phytoestrogen derivatives differentially inhibit arterial neointimal proliferation in a mouse model. PubMed: The vascular activity of some isoflavone metabolites: implications for a cardioprotective role. PubMed: Production of phytoestrogen S-equol from daidzein in mixed culture of two anaerobic bacteria. PubMed: Metabolism of daidzein by intestinal bacteria from rhesus monkeys (Macaca mulatta). PubMed: Simultaneous determination of 11 phytoestrogens in human serum using a 2 min liquid chromatography/tandem mass spectrometry method. PubMed: Biotransformation of daidzein to equol by crude enzyme from Asaccharobacter celatus AHU1763 required an anaerobic environment. PubMed: Is equol production beneficial to health? PubMed: The role of diet in the metabolism of daidzein by human faecal microbiota sampled from Italian volunteers. PubMed: A simple method for the characterization and quantification of soy isoflavone metabolites in the serum of MMTV-Neu mice using high-performance liquid chromatography/electrospray ionization mass spectrometry with multiple reaction monitoring. PubMed: Metabolism of daidzein by fecal bacteria in rats. PubMed: Isolation and characterisation of an equol-producing mixed microbial culture from a human faecal sample and its activity under gastrointestinal conditions. PubMed: Improved in vitro assays of superoxide anion and 1,1-diphenyl- 2-picrylhydrazyl (DPPH) radical-scavenging activity of isoflavones and isoflavone metabolites. PubMed: Urinary metabolites as biomarkers of polyphenol intake in humans: a systematic review. PubMed: Overnight urinary excretion of isoflavones as an indicator for dietary isoflavone intake in Korean girls of pubertal age. PubMed: Urine accurately reflects circulating isoflavonoids and ascertains compliance during soy intervention. PubMed: Urinary isoflavones are increased in adults, but decreased in children, consuming soy when on oral antibiotic therapy. PubMed: Conversion of daidzein and genistein by an anaerobic bacterium newly isolated from the mouse intestine. PubMed: Development of a high-throughput LC/APCI-MS method for the determination of thirteen phytoestrogens including gut microbial metabolites in human urine and serum. PubMed: Long-term dietary habits affect soy isoflavone metabolism and accumulation in prostatic fluid in caucasian men. PubMed: Synthesis of phytoestrogenic isoflavonoid disulfates. PubMed: Cardiovascular protective effects of synthetic isoflavone derivatives in apolipoprotein e-deficient mice. PubMed: Assessment of dietary isoflavone intake among middle-aged Chinese men. PubMed: Identification of puerarin and its metabolites in rats by liquid chromatography-tandem mass spectrometry. PubMed: Cosupplementation of isoflavones, prenylflavonoids, and lignans alters human exposure to phytoestrogen-derived 17beta-estradiol equivalents. PubMed: Quantitative determination of acetyl glucoside isoflavones and their metabolites in human urine using combined liquid chromatography-mass spectrometry. PubMed: Production of equol from daidzein by gram-positive rod-shaped bacterium isolated from rat intestine. PubMed: Interactions of phytoestrogens with estrogen receptors alpha and beta (III). Estrogenic activities of soy isoflavone aglycones and their metabolites isolated from human urine. PubMed: Variations in metabolism of the soy isoflavonoid daidzein by human intestinal microfloras from different individuals. PubMed: Isolation of an anaerobic intestinal bacterium capable of cleaving the C-ring of the isoflavonoid daidzein. PubMed: Isolation of human intestinal bacteria metabolizing the natural isoflavone glycosides daidzin and genistin. PubMed: A urinary profile study of dietary phytoestrogens. The identification and mode of metabolism of new isoflavonoids. PubMed: Gastrointestinal absorption and metabolism of soy isoflavonoids in ileal-canulated swine. PubMed: Oral antibiotics decrease urinary isoflavonoid excretion in children after soy consumption. PubMed: Supplementation of difructose anhydride III enhanced elevation of plasma equol concentrations and lowered plasma total cholesterol in isoflavone-fed rats. PubMed: Antipyretic, analgesic and muscle relaxant activities of pueraria isoflavonoids and their metabolites from Pueraria lobata Ohwi-a traditional Chinese drug. PubMed: DPPH radical-scavenging compounds from dou-chi, a soybean fermented food. PubMed: In vitro incubation of human feces with daidzein and antibiotics suggests interindividual differences in the bacteria responsible for equol production. PubMed: Plasma isoflavone levels versus self-reported soy isoflavone levels in Asian-American women in Los Angeles County. PubMed: Treatment with antibiotics reduces plasma equol concentration in cynomolgus monkeys (Macaca fascicularis). PubMed: Isoflavonoid and lignan phytoestrogens as dietary biomarkers. PubMed: Characterization of isoflavones and their conjugates in female rat urine using LC/MS/MS. PubMed: The correlation between dietary soy phytoestrogens and neuropathic pain behavior in rats after partial denervation. PubMed: Synthesis of novel mammalian metabolites of the isoflavonoid phytoestrogens daidzein and genistein. PubMed: A novel radioimmunoassay for daidzein. PubMed: Metabolism of daidzein and genistein by intestinal bacteria. PubMed: Metabolites of dietary (soya) isoflavones in human urine. PubMed: Isolation and characterization of a novel equol-producing bacterium from human feces. PubMed: Receptor binding and transactivation activities of red clover isoflavones and their metabolites. PubMed: Isoflavonoid glucosides are deconjugated and absorbed in the small intestine of human subjects with ileostomies. PubMed: Isoflavone metabolites and their in vitro dual functions: they can act as an estrogenic agonist or antagonist depending on the estrogen concentration. PubMed: Prostatic fluid concentrations of isoflavonoids in soy consumers are sufficient to inhibit growth of benign and malignant prostatic epithelial cells in vitro. PubMed: Characterization and quantification of soy isoflavone metabolites in serum of renal transplanted patients by high-performance liquid chromatography/electrospray ionization mass spectrometry. PubMed: Time-resolved fluoroimmunoassay of plasma and urine O-desmethylangolensin. PubMed: Liquid chromatographic-photodiode array mass spectrometric analysis of dietary phytoestrogens from human urine and blood. PubMed: Hydrolysis of isoflavone glycosides to aglycones by beta-glycosidase does not alter plasma and urine isoflavone pharmacokinetics in postmenopausal women. PubMed: Analysis of plasma isoflavones by reversed-phase HPLC-multiple reaction ion monitoring-mass spectrometry.