D-mevalonolactone
2H-pyran-2-one, tetrahydro-4-hydroxy-4-methyl-, (4R)-
Identification
| Name | D-mevalonolactone |
| IUPAC | (4R)-4-hydroxy-4-methyloxan-2-one |
| CAS Number | 19115-49-2 |
| FDA UNII | 661X270Z3L |
| Molecular Formula | C6 H10 O3 |
| Molecular Weight | 130.14330000 |
| MDL Number | MFCD01074894 |
| Nikkaji Number | J37.661B |
| XlogP3 | -0.30 (est) |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 1e+006 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | information only not used for fragrances or flavors |
| Recommendation for D-mevalonolactone usage levels up to | not for fragrance use. |
| Recommendation for D-mevalonolactone flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
(4R)-4-
hydroxy-4-methyloxan-2-one
(4R)-4-
hydroxy-4-methyltetrahydro-2H-pyran-2-one
b-
hydroxy-b-methyl-d-valerolactone
(-)-(R)-
mevalonic acid lactone
D-
mevalonic Acid Lactone
(-)-
mevalonolactone
(-)-(R)-
mevalonolactone
(3R)-
mevalonolactone
(R)-
mevalonolactone
mevalonolactone, (-)-
mevalonolactone, (R)-isomer
2H-
pyran-2-one, tetrahydro-4-hydroxy-4-methyl-, (4R)-
2H-
pyran-2-one, tetrahydro-4-hydroxy-4-methyl-, (R)-
PubMed:
(-)-R-mevalonolactone studied by ROA and SERS spectroscopy.
PubMed:
Polyketides from the littoral plant associated fungus Pseudallescheria boydii.
PubMed:
A mild, palladium-catalyzed method for the dehydrohalogenation of alkyl bromides: synthetic and mechanistic studies.
PubMed:
Cytotoxic pentacyclic and tetracyclic aromatic sesquiterpenes from Phomopsis archeri.
PubMed:
Cytotoxic cardenolides from the leaves of Calotropis gigantea.
PubMed:
Cloning and characterization of a novel gene that encodes (S)-beta-bisabolene synthase from ginger, Zingiber officinale.
PubMed:
Cytotoxic substances produced by a fungal strain from a sponge: physico-chemical properties and structures.
PubMed:
Feasibility of an immunoassay for mevalonolactone.
PubMed:
Chloroperoxidase as Enantioselective Epoxidation Catalyst: An Efficient Synthesis of (R)-(-)-Mevalonolactone.
PubMed:
Regulation of cholesterol synthesis in primary rat hepatocyte culture cells. Possible regulatory site at sterol demethylation.