(±)-pantothenol

butyramide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, DL-

CAS: 16485-10-2 C9 H19 N O4 MW: 205.25423000

Identification

Name(±)-pantothenol
IUPAC2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide
CAS Number16485-10-2
EINECS240-540-6
FDA UNIIWV9CM0O67Z
Molecular FormulaC9 H19 N O4
Molecular Weight205.25423000
MDL NumberMFCD00002944
Nikkaji NumberJ321.113D
Beilstein1724947

Regulatory

Physical Properties

Food Chemicals Codex Listed No
Boiling Point 483.60 °C. @ 760.00 mm Hg (est)
Vapor Pressure 1.500000 mmHg @ 25.00 °C. (est)
Flash Point 475.00 °F. TCC ( 246.30 °C. ) (est)
logP (o/w) -0.989 (est)
Soluble in water, 1e+006 mg/L @ 25 °C (est)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesantistatic agents

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityintraperitoneal-mouse LD50 10100 mg/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorycosmetic agents
Recommendation for (±)-pantothenol usage levels up tonot for fragrance use.

American International Chemical, Inc.

Consistent sources

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Jiangyin Healthway International Trade Co., Ltd

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

alcopan-250 bepanthen bepantol butanamide, 2, 4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl- butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl- butyramide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, DL- (±)- cozyme dexpanthenolum (±)-2,4- dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide 2,4- dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide (±)-2,4- dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide 2,4- dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide DL-2,4- dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide fancol DL ilopan intrapan panadon pantenolo panthenol DL- panthenol panthoderm pantol pantothenol DL- pantothenol DL- pantothenyl alcohol N- pantoyl-3-propanolamine N- pantoyl-propanolamine penthenol propanolamine, N-pantoyl- provitamin B synapan urupan varitan PubMed: Antimicrobial activity of pantothenol against staphylococci possessing a prokaryotic type II pantothenate kinase. PubMed: Amniotic fluid metabolomic analysis in spontaneous preterm birth. PubMed: [Ion-pair HPLC analysis of B vitamins in syrup products in Indonesia]. PubMed: Location and conformation of pantothenate and its derivatives in Mycobacterium tuberculosis pantothenate kinase: insights into enzyme action. PubMed: Calcium pantothenate modulates gene expression in proliferating human dermal fibroblasts. PubMed: How pantothenol intervenes in Coenzyme-A biosynthesis of Mycobacterium tuberculosis. PubMed: Feedback inhibition of pantothenate kinase regulates pantothenol uptake by the malaria parasite. PubMed: Provitamin B5 (pantothenol) inhibits growth of the intraerythrocytic malaria parasite. PubMed: In vitro release study of transdermal delivery systems of progesterone. PubMed: Pantothenic acid and pantothenol increase biosynthesis of glutathione by boosting cell energetics. PubMed: Effect of urea and pantothenol on the permeation of progesterone through excised rat skin from polymer matrix systems. PubMed: Protection by pantothenol and beta-carotene against liver damage produced by low-dose gamma radiation. PubMed: Pantothenol protects rats against some deleterious effects of gamma radiation. PubMed: Protective effect of pantothenic acid and related compounds against permeabilization of Ehrlich ascites tumour cells by digitonin. PubMed: Pantothenic acid and its derivatives protect Ehrlich ascites tumor cells against lipid peroxidation. PubMed: Dilated cardiomyopathy due to type II X-linked 3-methylglutaconic aciduria: successful treatment with pantothenic acid. PubMed: Freeze-drying of oxyhemoglobin: protection against oxidation in the presence of EDTA salts, sulfonic acid buffers, and pantothenic acid derivatives. PubMed: Semiautomated method for microbiological vitamin assays. PubMed: [The influence of gamma-irradiation on pantothenol and calcium pantothenate in acqueous solution]. PubMed: [Animal experiment studies on the position of pantothenol among the curare antagonists]. PubMed: [USE OF PANTOTHENOL (BEPANTOL) IN THE TREATMENT OF HERPES ZOSTER]. PubMed: [COMMENTS ON THE PHARMACOPOEA NORDICA, VOL. IV. MICROBIOLOGICAL DETERMINATION OF THE STRENGTH OF PANTOTHENOL]. PubMed: [DETERMINATION OF PANTOTHENOL IN VARIOUS DRUG FORMS. I. COLORIMETRIC DETERMINATION IN PREPARATIONS AND SOLUTIONS FOR INJECTIONS]. PubMed: [MICROBIOLOGICAL DETERMINATION OF PANTOTHENOL USING LEUCONOSTOC MESENTEROIDES. EVALUATION OF THE METHOD AND ITS ADVANTAGES]. PubMed: [Activity of pantothenol on juxta-epiphyseal cartilage in normal and hypophysectomized rats]. PubMed: Pantothenol and the burning feet syndrome. PubMed: [Treatment of the chronic constipation of age with pantothenol]. PubMed: Activity of pantothenol as pantothenic acid in promoting chick growth.