(±)-thioctic acid

acid, a-lipoic alphaflam alphalipogamma alphalipoic acid alphaLippon AL alphavibolex azulipont biletan biomo lipon biomo-lipon biomolipon 6,8- dihydrothioctic acid 5-( dithiolan-3-yl) valeric acid 5-( dithiolan-3-yl)pentanoic acid 5-(1,2- dithiolan-3-yl)pentanoic acid 5-( dithiolan-3-yl)valeric acid 5-(1,2- dithiolan-3-yl)valeric acid (±)-1,2- dithiolane-3-pentanoic acid 1,2- dithiolane-3-pentanoic acid (±)-1,2- dithiolane-3-valeric acid 1,2- dithiolane-3-valeric acid DL-1,2- dithiolane-3-valeric acid 5-[3-(1,2- dithiolanyl)]pentanoic acid 6,8- dithiooctanoic acid DL-6,8- dithiooctanoic acid duralipon espa lipon espa-lipon espalipon fenint a- lipogamma lipoic acid (±)- lipoic acid (±)-a- lipoic acid (RS)- lipoic acid (RS)-a- lipoic acid a- lipoic acid alpha- lipoic acid DL- lipoic acid DL-a- lipoic acid lipoicacid a- lipon stada a- liponaure heumann liponic acid a- liponic acid a- liponsaeure a- liponsaure sofotec liponsaure-ratiopharm liposan lipothion a- lippon AL neurium pleomix A pleomix-A pleomixalpha rac-lipoate thioctacid 6- thioctic acid 6,8- thioctic acid DL- thioctic acid DL-6- thioctic acid DL-6,8- thioctic acid thioctic acid DL-form DL- thiocticacid thiogamma oral thiooctic acid 6- thiotic acid 6,8- thiotic acid thiotomin tromlipon verla lipon verla-lipon verlalipon a- vibolex PubMed: α-Lipoic acid reduces fatty acid esterification and lipogenesis in adipocytes from overweight/obese subjects. PubMed: The effect of dietary α-lipoic acid, betaine, l-carnitine, and swimming on the obesity of mice induced by a high-fat diet. PubMed: α-Tocopherol supplementation reduces biomarkers of oxidative stress in children with Down syndrome: a randomized controlled trial. PubMed: Effect of dietary α-lipoic acid on the mRNA expression of genes involved in drug metabolism and antioxidation system in rat liver. PubMed: Phosphorylation of hypothalamic AMPK on serine(485/491) related to sustained weight loss by alpha-lipoic acid in mice treated with olanzapine. PubMed: Wheat germ oil enrichment in broiler feed with α-lipoic acid to enhance the antioxidant potential and lipid stability of meat. PubMed: Effects of combined lipoic acid and pyridoxine on albuminuria, advanced glycation end-products, and blood pressure in diabetic nephropathy. PubMed: Efficacy of food supplement to improve metabolic syndrome parameters in patients affected by moderate to severe psoriasis during anti-TNFα treatment. PubMed: R-α lipoic acid γ-cyclodextrin complex increases energy expenditure: a 4-month feeding study in mice. PubMed: Protective effect of alpha-lipoic acid on cypermethrin-induced oxidative stress in Wistar rats. PubMed: Rapid Method for Glutathione Quantitation Using High-Performance Liquid Chromatography with Coulometric Electrochemical Detection. PubMed: The effects of α-lipoic acid on liver oxidative stress and free fatty acid composition in methionine-choline deficient diet-induced NAFLD. PubMed: Wheat germ oil and α-lipoic acid predominantly improve the lipid profile of broiler meat. PubMed: Acetyl-L-carnitine and lipoic acid improve mitochondrial abnormalities and serum levels of liver enzymes in a mouse model of nonalcoholic fatty liver disease. PubMed: Characterization of genome-wide transcriptional changes in liver and adipose tissues of ZDF (fa/fa) rats fed R-α-lipoic acid by next-generation sequencing. PubMed: Asparagusic acid. PubMed: Calorie restriction and dietary restriction mimetics: a strategy for improving healthy aging and longevity. PubMed: Comprehensive rehabilitation in chronic heart failure. PubMed: Attenuation of uremia by orally feeding alpha-lipoic acid on acetaminophen induced uremic rats. PubMed: Reduction of aggregation of β-lactoglobulin during heating by dihydrolipoic acid. PubMed: Role of α-lipoic acid in dextran sulfate sodium-induced ulcerative colitis in mice: studies on inflammation, oxidative stress, DNA damage and fibrosis. PubMed: The endocrine control of energy homeostasis in chickens. PubMed: The protective effect of alpha-lipoic Acid in lipopolysaccharide-induced acute lung injury is mediated by heme oxygenase-1. PubMed: The effect of alpha-lipoic acid on mitochondrial superoxide and glucocorticoid-induced hypertension. PubMed: Α-lipoic acid supplementation up-regulates antioxidant capacity in adults with G6PD deficiency. PubMed: Lipoic acid inhibits adiponectin production in 3T3-L1 adipocytes. PubMed: Direct and indirect antioxidant properties of α-lipoic acid and therapeutic potential. PubMed: Formation of stable nanocarriers by in situ ion pairing during block-copolymer-directed rapid precipitation. PubMed: Synthesis and bioactivity profile of 5-s-lipoylhydroxytyrosol-based multidefense antioxidants with a sizeable (poly)sulfide chain. PubMed: Molecular characterization of a thermostable aldehyde dehydrogenase (ALDH) from the hyperthermophilic archaeon Sulfolobus tokodaii strain 7. PubMed: The effects of alpha lipoic acid on liver cells damages and apoptosis induced by polyunsaturated fatty acids. PubMed: Kinetic modeling and scale up of lipoic acid (LA) production from Saccharomyces cerevisiae in a stirred tank bioreactor. PubMed: Alpha-lipoic acid protects against indomethacin-induced gastric oxidative toxicity by modulating antioxidant system. PubMed: Effects of lipoic acid on lipolysis in 3T3-L1 adipocytes. PubMed: A combination cocktail improves spatial attention in a canine model of human aging and Alzheimer's disease. PubMed: Effects of heat treatment on structural modification and in vivo antioxidant capacity of soy protein. PubMed: Determination of lipoic acid by flow-injection and high-performance liquid chromatography with chemiluminescence detection. PubMed: α-Lipoic acid reduced weight gain and improved the lipid profile in rats fed with high fat diet. PubMed: High-fat diets impair spatial learning of mice in the Y-maze paradigm: ameliorative potential of α-lipoic acid. PubMed: Combined effect of sesamin and α-lipoic acid on hepatic fatty acid metabolism in rats. PubMed: Effects of lipoic acid on AMPK and adiponectin in adipose tissue of low- and high-fat-fed rats. PubMed: A combination of lipoic acid plus coenzyme Q10 induces PGC1α, a master switch of energy metabolism, improves stress response, and increases cellular glutathione levels in cultured C2C12 skeletal muscle cells. PubMed: Enhancement of lipid stability of broiler breast meat and meat products fed on alpha lipoic acid and alpha tocopherol acetate supplemented feed. PubMed: Lipoic acid mitigates bisphenol A-induced testicular mitochondrial toxicity in rats. PubMed: Development of a simple and high-throughput method for detecting aflatoxins production in culture media. PubMed: Lipoic acid administration prevents nonalcoholic steatosis linked to long-term high-fat feeding by modulating mitochondrial function. PubMed: Lipoic acid improves mitochondrial function in nonalcoholic steatosis through the stimulation of sirtuin 1 and sirtuin 3. PubMed: Lipoic acid attenuates high-fat-diet-induced oxidative stress and B-cell-related immune depression. PubMed: Bioactive compounds with effects on inflammation markers in humans. PubMed: Effects of α-lipoic acid and L-carnosine supplementation on antioxidant activities and lipid profiles in rats. PubMed: Fatty acids and gene expression responses to bioactive compounds in Atlantic salmon (Salmo salar L.) hepatocytes. PubMed: Direct analysis of carbohydrates in animal plasma by ion chromatography coupled with mass spectrometry and pulsed amperometric detection for use as a non-invasive diagnostic tool. PubMed: Novel Conjugates of 1,3-Diacylglycerol and Lipoic Acid: Synthesis, DPPH Assay, and RP-LC-MS-APCI Analysis. PubMed: Impact of α-lipoic acid on liver peroxisome proliferator-activated receptor-α, vascular remodeling, and oxidative stress in insulin-resistant rats. PubMed: Alpha-lipoic acid protects against myocardial ischemia/reperfusion injury via multiple target effects. PubMed: Lipid stability and antioxidant profile of microsomal fraction of broiler meat enriched with α-lipoic acid and α-tocopherol acetate. PubMed: Effects of α-lipoic acid, vitamins E and C upon the heat stress in Japanese quails. PubMed: Reciprocal effects of α-lipoic acid on adenosine monophosphate-activated protein kinase activity in obesity induced by ovariectomy in rats. PubMed: Effects of lipoic acid on apelin in 3T3-L1 adipocytes and in high-fat fed rats. PubMed: A Regenerative Antioxidant Protocol of Vitamin E and α-Lipoic Acid Ameliorates Cardiovascular and Metabolic Changes in Fructose-Fed Rats. PubMed: Inhibitory effect of α-lipoic acid on platelet aggregation is mediated by PPARs. PubMed: Lipoic acid inhibits leptin secretion and Sp1 activity in adipocytes. PubMed: Effects of lipoic acid on proliferation and apoptosis of liver cells in rats with metabolic stress. PubMed: Formulation of a medical food cocktail for Alzheimer's disease: beneficial effects on cognition and neuropathology in a mouse model of the disease. PubMed: Vitamin C, resveratrol and lipoic acid actions on isolated rat liver mitochondria: all antioxidants but different. PubMed: Pharmacokinetics of orally administered DL-α-lipoic acid in dogs. PubMed: The proglycation effect of caffeic acid leads to the elevation of oxidative stress and inflammation in monocytes, macrophages and vascular endothelial cells. PubMed: Lipoic acid nanoparticles: effect of polymeric stabilizer on appetite suppression. PubMed: Antiplatelet activity of alpha-lipoic acid. PubMed: Comparative proteome analysis of splenic lymphocytes in long-term high-fat diet and dietary supplement with lipoic acid mice. PubMed: Cytoprotective effects of DL-alpha-lipoic acid or squalene on cyclophosphamide-induced oxidative injury: an experimental study on rat myocardium, testicles and urinary bladder. PubMed: Protective effect of lipoic acid against methotrexate-induced oxidative stress in liver mitochondria. PubMed: Effects of duodenal redox status on calcium absorption and related genes expression in high-fat diet-fed mice. PubMed: Role of oxidative stress and nitric oxide in the protective effects of alpha-lipoic acid and aminoguanidine against isoniazid-rifampicin-induced hepatotoxicity in rats. PubMed: Effect of POLY-MVA, a palladium alpha-lipoic acid complex formulation against declined mitochondrial antioxidant status in the myocardium of aged rats. PubMed: Dyslipidemic high-fat diet affects adversely bone metabolism in mice associated with impaired antioxidant capacity. PubMed: Reactive oxygen species serve as signals mediating glucose-stimulated somatostatin secretion from cultured rat gastric primary D-cells. PubMed: Vitamin E as a novel enhancer of macroautophagy in rat hepatocytes and H4-II-E cells. PubMed: Lipoic acid: an immunomodulator that attenuates glycinin-induced anaphylactic reactions in a rat model. PubMed: A new method for the detection and characterization of alpha-lipoic acid mixed disulphides. PubMed: Effects of alpha-lipoic acid on cell proliferation and apoptosis in MDA-MB-231 human breast cells. PubMed: Improved efficacy of appetite suppression by lipoic acid particles prepared by nanocomminution. PubMed: Lipoic acid attenuates high fat diet-induced chronic oxidative stress and immunosuppression in mice jejunum: a microarray analysis. PubMed: Mechanism of alpha-lipoic acid-induced apoptosis of lung cancer cells. PubMed: Prevention of high-fat diet-induced muscular lipid accumulation in rats by alpha lipoic acid is not mediated by AMPK activation. PubMed: Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential. PubMed: Lipoic acid prevents body weight gain induced by a high fat diet in rats: effects on intestinal sugar transport. PubMed: Effects of antioxidant supplements intervention on the level of plasma inflammatory molecules and disease severity of rheumatoid arthritis patients. PubMed: Electrochemical immunosensor for detection of celiac disease toxic gliadin in foodstuff. PubMed: The effect of lipoic acid on macro and trace metal levels in living tissues exposed to oxidative stress. PubMed: Palladium alpha-lipoic acid complex formulation enhances activities of Krebs cycle dehydrogenases and respiratory complexes I-IV in the heart of aged rats. PubMed: Foods and supplements in the management of migraine headaches. PubMed: Protective effect of lipoic acid against acrolein-induced cytotoxicity in IMR-90 human fibroblasts. PubMed: A piezoelectric immunosensor for the determination of pesticide residues and metabolites in fruit juices. PubMed: Carotenoid extraction from plants using a novel, environmentally friendly solvent. PubMed: Chronic lipoic acid treatment worsens energy imbalances in streptozotocin-induced diabetic rats. PubMed: [Effect of lipoic acid on gene expression related to oxidative stress, lipid and glucose metabolism of mice fed with high fat diet]. PubMed: Dihydrolipoic acid inhibits tetrachlorohydroquinone-induced tumor promotion through prevention of oxidative damage. PubMed: Dietary lipoic acid supplementation can mimic or block the effect of dietary restriction on life span. PubMed: Chitosan microspheres for encapsulation of alpha-lipoic acid. PubMed: Lipoic acid prevents high-fat diet-induced dyslipidemia and oxidative stress: a microarray analysis. PubMed: Dietary lipoic acid-dependent changes in the activity and mRNA levels of hepatic lipogenic enzymes in rats. PubMed: Nonvitamin, nonmineral dietary supplementation in HIV-positive people. PubMed: [Safety and structural analysis of polymers produced in manufacturing process of alpha-lipoic acid]. PubMed: alpha-Lipoic acid in dietary supplements: development and comparison of HPLC-CEAD and HPLC-ESI-MS methods. PubMed: Comparison of the total oxyradical scavenging capacity and oxygen radical absorbance capacity antioxidant assays. PubMed: S-allylcysteine scavenges singlet oxygen and hypochlorous acid and protects LLC-PK(1) cells of potassium dichromate-induced toxicity. PubMed: Transepithelial transport of alpha-lipoic acid across human intestinal Caco-2 cell monolayers. PubMed: Protection against arsenic trioxide-induced autophagic cell death in U118 human glioma cells by use of lipoic acid. PubMed: Effect of antioxidant capacity on blood lipid metabolism and lipoprotein lipase activity of rats fed a high-fat diet. PubMed: Paraquat-induced oxidative stress in drosophila melanogaster: effects of melatonin, glutathione, serotonin, minocycline, lipoic acid and ascorbic acid. PubMed: Safety evaluation of alpha-lipoic acid (ALA). PubMed: Long-term safety of alpha-lipoic acid (ALA) consumption: A 2-year study. PubMed: Dietary antioxidants and behavioral enrichment enhance neutrophil phagocytosis in geriatric Beagles. PubMed: [The role of antioxidants in prevention]. PubMed: Alpha-lipoic acid prevents lipotoxic cardiomyopathy in acyl CoA-synthase transgenic mice. PubMed: Diabetes--a man made disease. PubMed: Obesity: the role of hypothalamic AMP-activated protein kinase in body weight regulation. PubMed: alpha-Lipoic acid induces apoptosis in human colon cancer cells by increasing mitochondrial respiration with a concomitant O2-*-generation. PubMed: Role of hypothalamic 5'-AMP-activated protein kinase in the regulation of food intake and energy homeostasis. PubMed: The role of antioxidant micronutrients in the prevention of diabetic complications. PubMed: Increasing trends in elderly persons' use of nonvitamin, nonmineral dietary supplements and concurrent use of medications. PubMed: alpha-Lipoic acid prevents diabetes mellitus in diabetes-prone obese rats. PubMed: Alpha-lipoic acid, an anti-obesity agent? PubMed: Determination of lipoic acid in dietary supplement preparations by capillary electrophoresis. PubMed: The effects of the antioxidant lipoic acid on beef longissimus bloom time. PubMed: Effects of alpha-lipoic acid supplementation on maternal diabetes-induced growth retardation and congenital anomalies in rat fetuses. PubMed: Natural antioxidants and neurodegenerative diseases. PubMed: [Effects of DL-alpha-lipoic acid on the experimentally induced diabetic cataract in rats]. PubMed: Effects of a medium chain triglyceride oil mixture and alpha-lipoic acid diet on body composition, antioxidant status, and plasma lipid levels in the Golden Syrian hamster. PubMed: Anti-obesity effects of alpha-lipoic acid mediated by suppression of hypothalamic AMP-activated protein kinase. PubMed: Prior experience, antioxidants, and mitochondrial cofactors improve cognitive function in aged beagles. PubMed: Long-term treatment with antioxidants and a program of behavioral enrichment reduces age-dependent impairment in discrimination and reversal learning in beagle dogs. PubMed: Redox regulation of mitochondrial permeability transition: effects of uncoupler, lipoic acid and its positively charged analog LA-plus and selenium. PubMed: Copper toxicity, oxidative stress, and antioxidant nutrients. PubMed: Demonstration of labeless detection of food pathogens using electrochemical redox probe and screen printed gold electrodes. PubMed: Mercury toxicity and antioxidants: Part 1: role of glutathione and alpha-lipoic acid in the treatment of mercury toxicity. PubMed: Alpha-lipoic acid inhibits glycogen synthesis in rat soleus muscle via its oxidative activity and the uncoupling of mitochondria. PubMed: Safety of long-term feeding of dl-alpha-lipoic acid and its effect on reduced glutathione:oxidized glutathione ratios in beagles. PubMed: Alpha-lipoic acid modulates NF-kappaB activity in human monocytic cells by direct interaction with DNA. PubMed: Lipoic acid improves survival in transgenic mouse models of Huntington's disease. PubMed: Chronic fatigue syndrome: oxidative stress and dietary modifications. PubMed: Cataract development in diabetic sand rats treated with alpha-lipoic acid and its gamma-linolenic acid conjugate. PubMed: Ability of amino acids, dipeptides, polyamines, and sulfhydryls to quench hexanal, a saturated aldehydic lipid oxidation product. PubMed: Ability of carnosine and other skeletal muscle components to quench unsaturated aldehydic lipid oxidation products. PubMed: Chromatographic analysis of lipoic acid and related compounds. PubMed: Age-associated decline in ascorbic acid concentration, recycling, and biosynthesis in rat hepatocytes--reversal with (R)-alpha-lipoic acid supplementation. PubMed: Influence of food intake on the bioavailability of thioctic acid enantiomers. PubMed: Inhibition of lecithin: cholesterol acyltransferase activity in human blood plasma by cigarette smoke extract and reactive aldehydes. PubMed: Amanita poisoning during the second trimester of pregnancy. A case report and a review of the literature. PubMed: Cardiac recovery during post-ischemic reperfusion is improved by combination of vitamin E with dihydrolipoic acid. PubMed: Determination of lipoic acid in meat of commercial quality. PubMed: Development of an improved chemically defined minimal medium for Listeria monocytogenes.