oxothiazolidinecarboxylic acid

koprosteine procysteine oxo thiazolidine carboxylate, L- (-)-2-oxo-4- thiazolidine carboxylic acid L-2-oxo thiazolidine-4-carboxylate laevo-2-oxo thiazolidine-4-carboxylate 2-oxo thiazolidine-4-carboxylate, L- (4R)-2-oxo-1,3- thiazolidine-4-carboxylic acid 2-oxo thiazolidine-4-carboxylic acid (-)-2-oxo-4- thiazolidinecarboxylic acid (R)-2-oxo-4- thiazolidinecarboxylic acid L-2-oxo-4- thiazolidinecarboxylic acid 4- thiazolidinecarboxylic acid, 2-oxo-, (4R)- 4- thiazolidinecarboxylic acid, 2-oxo-, (R)- 4- thiazolidinecarboxylic acid, 2-oxo-, L- PubMed: Effect of procysteine on aging-associated changes in hepatic GSH and SMase: evidence for transcriptional regulation of smpd3. PubMed: Dietary antioxidants prevent alcohol-induced ciliary dysfunction. PubMed: Protective effect of procysteine on Acinetobacter pneumonia in hyperoxic conditions. PubMed: The role of mitochondrial oxidation in endotoxin-induced liver-dependent swine pulmonary edema. PubMed: Chronic alcohol ingestion exacerbates lung epithelial barrier dysfunction in HIV-1 transgenic rats. PubMed: Thiols stabilize cobblestone morphology of cultured mesothelial cells. PubMed: Non-invasive monitoring of L-2-oxothiazolidine-4-carboxylate metabolism in the rat brain by in vivo 13C magnetic resonance spectroscopy. PubMed: Procysteine increases alcohol-depleted glutathione stores in rat plantaris following a period of abstinence. PubMed: Cigarette smoke-induced changes to alveolar macrophage phenotype and function are improved by treatment with procysteine. PubMed: Procysteine stimulates expression of key anabolic factors and reduces plantaris atrophy in alcohol-fed rats. PubMed: Vascular oxidative stress and nitric oxide depletion in HIV-1 transgenic rats are reversed by glutathione restoration. PubMed: Alveolar type II cells from ethanol-fed rats produce a fibronectin-enriched extracellular matrix that promotes monocyte activation. PubMed: Oxidant-induced atrogin-1 and transforming growth factor-beta1 precede alcohol-related myopathy in rats. PubMed: Glutathione availability modulates alveolar macrophage function in the chronic ethanol-fed rat. PubMed: Angiotensin II mediates glutathione depletion, transforming growth factor-beta1 expression, and epithelial barrier dysfunction in the alcoholic rat lung. PubMed: Glutathione replacement preserves the functional surfactant phospholipid pool size and decreases sepsis-mediated lung dysfunction in ethanol-fed rats. PubMed: Chronic ethanol ingestion potentiates TNF-alpha-mediated oxidative stress and apoptosis in rat type II cells. PubMed: Promoting glutathione synthesis after spinal cord trauma decreases secondary damage and promotes retention of function. PubMed: Novel drug development for amyotrophic lateral sclerosis. PubMed: Mitochondrial glutathione replacement restores surfactant synthesis and secretion in alveolar epithelial cells of ethanol-fed rats. PubMed: Ethanol ingestion via glutathione depletion impairs alveolar epithelial barrier function in rats. PubMed: The pharmacokinetics and pharmaco-dynamics of Procysteine in amyotrophic lateral sclerosis. PubMed: Protection by L-2-oxothiazolidine-4-carboxylic acid of hydrogen peroxide-induced CD3zeta and CD16zeta chain down-regulation in human peripheral blood lymphocytes and lymphokine-activated killer cells. PubMed: Elevation of whole-blood glutathione in peritoneal dialysis patients by L-2-oxothiazolidine-4-carboxylate, a cysteine prodrug (Procysteine). PubMed: A phase I/II evaluation of oral L-2-oxothiazolidine-4-carboxylic acid in asymptomatic patients infected with human immunodeficiency virus. PubMed: A trial of antioxidants N-acetylcysteine and procysteine in ARDS. The Antioxidant in ARDS Study Group. PubMed: L-2-oxothiazolidine-4-carboxylic acid inhibits human immunodeficiency virus type 1 replication in mononuclear phagocytes and lymphocytes. PubMed: Protective effects of L-2-oxothiazolidine-4-carboxylate treatment on cyclophosphamide-induced cystitis in rats. PubMed: Supplementation with L-2-oxothiazolidine-4-carboxylic acid, a cysteine precursor, does not protect against lipid peroxidation in puromycin aminonucleoside-induced nephropathy. PubMed: Increased gamma-glutamylcysteine synthetase and gamma-glutamyl transpeptidase activities enhance resistance of rat lung epithelial L2 cells to quinone toxicity. PubMed: L-2-oxothiazolidine-4-carboxylic acid (procysteine) inhibits expression of the human immunodeficiency virus and expression of the interleukin-2 receptor alpha chain. PubMed: Determination of L-2-oxothiazolidine-4-carboxylic acid (Procysteine) in human plasma by high-performance liquid chromatography. PubMed: A phase I/II trial of intravenous L-2-oxothiazolidine-4-carboxylic acid (procysteine) in asymptomatic HIV-infected subjects. PubMed: Toxicity evaluations of L-cysteine and Procysteine, a cysteine prodrug, given once intravenously to neonatal rats. PubMed: Enhancement of viability of human peritoneal mesothelial cells with glutathione precursor: L-2-oxothiazolidine-4-carboxylate.