tetrandrine
berbaman, 6,6',7,12-tetramethoxy-2,2'-dimethyl-, (1b)- (9CI)
Identification
| Name | tetrandrine |
| CAS Number | 518-34-3 |
| FDA UNII | 29EX23D5AJ |
| Molecular Formula | C38 H42 N2 O6 |
| Molecular Weight | 622.76194000 |
| MDL Number | MFCD08689909 |
| Nikkaji Number | J130.138A |
| Beilstein | 0877811 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 217.50 °C. @ 760.00 mm Hg |
| Boiling Point | 710.50 °C. @ 760.00 mm Hg (est) |
| Flash Point | 348.00 °F. TCC ( 175.80 °C. ) (est) |
| logP (o/w) | 3.550 (est) |
| Soluble in | water, 1.356e-005 mg/L @ 25 °C (est) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | skin conditioning |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | intravenous-cat LDLo 40 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | cosmetic ingredient for skin conditioning |
| Recommendation for tetrandrine usage levels up to | not for fragrance use. |
| Recommendation for tetrandrine flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
berbaman, 6,6',7,12-tetramethoxy-2,2'-dimethyl-, (1b)- (9CI)
fanchinine
hanfangchin A
sinomenine A
(1b)-6,6,7,12-
tetramethoxy-2,2?-dimethylberbaman
(1b)-6,6',7,12-
tetramethoxy-2,2'-dimethylberbaman
tetrandrin
(+)-
tetrandrine
(S,S)-
tetrandrine
(S,S)-(+)-
tetrandrine
PubMed:
The effects of acupuncture and traditional Chinese medicines on apoptosis of brain tissue in a rat intracerebral hemorrhage model.
PubMed:
Simultaneous Determination of Five Alkaloid Compounds in a Drug Based on a Hydrophilic Monolithic Column by Capillary Electrochromatography.
PubMed:
Organ-specific analysis of mahonia using gel-free/label-free proteomic technique.
PubMed:
Screening and identification of multiple constituents and their metabolites of Fangji Huangqi Tang in rats by ultra-high performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry basing on coupling data processing techniques.
PubMed:
Protective effects of tetrandrine on brain cells in phenobarbital-dependent and -withdrawn rats.
PubMed:
[Pharmacokinetics of fangchinoline and tetrandrine in rats].