hydrofluorocarbon 152A

1,1-difluoroethane

CAS: 75-37-6 C2 H4 F2 MW: 66.05068640

Identification

Namehydrofluorocarbon 152A
IUPAC1,1-difluoroethane
CAS Number75-37-6
EINECS200-866-1
FDA UNII0B1U8K2ME0
Molecular FormulaC2 H4 F2
Molecular Weight66.05068640
MDL NumberMFCD00000449
Nikkaji NumberJ2.819C
Beilstein1696900

Regulatory

DG SANTE Food Contact Materials1,1-difluoroethane
FDA Mainterm (IAUFC)75-37-6 ; 1,1-DIFLUOROETHANE

Physical Properties

Appearance colorless gas (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Melting Point -117.00 °C. @ 760.00 mm Hg (est)
Boiling Point -24.70 °C. @ 760.00 mm Hg (est)
Vapor Pressure 4550.000000 mmHg @ 25.00 °C. (est)
Vapor Density 2.3 ( Air = 1 )
Flash Point -80.00 °F. TCC ( -62.00 °C. ) (est)
logP (o/w) 0.750
Soluble in water, 3200 mg/L @ 21C (exp)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usespropellants

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityoral-rat LDLo > 1500 mg/kg
Dermal ToxicityNot determined
Inhalation Toxicityinhalation-mouse LC50 977000 mg/m3/2H

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorypropellants, aerating agents, and gas
Recommendation for hydrofluorocarbon 152A usage levels up tonot for fragrance use.
Recommendation for hydrofluorocarbon 152A flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

propellants

Natural Occurrence

not found in nature

Synonyms

algofrene type 67 1,1- difluoroethane dymel 152 dymel 152A ethane, 1,1-difluoro- ethylene fluoride ethylidene difluoride ethylidene fluoride FC 152A fluorocarbon 152A freon 152A genetron 100 genetron 152A halocarbon 152A HFC 152A HFC-152A HSDB 5205 R 152A refrigerant 152A PubMed: Blood and exhaled air can be used for biomonitoring of hydrofluorocarbon exposure. PubMed: Identification of volatiles by headspace gas chromatography with simultaneous flame ionization and mass spectrometric detection. PubMed: [In-situ measurement of background atmospheric HCFC-142b using GC-MS and GC-ECD method]. PubMed: Evaluation of left ventricular function by bedside ultrasound in acute toxic myocarditis. PubMed: Greenhouse gas emissions for refrigerant choices in room air conditioner units. PubMed: Deaths involving 1,1-difluoroethane at the San Diego County Medical Examiner's Office. PubMed: Triboelectricity: macroscopic charge patterns formed by self-arraying ions on polymer surfaces. PubMed: Dusting right under our nose: difluoroethane abuse in the emergency department. PubMed: Uptake and disposition of 1,1-difluoroethane (HFC-152a) in humans. PubMed: Ethanol analysis by headspace gas chromatography with simultaneous flame-ionization and mass spectrometry detection. PubMed: Inhalant abuse of computer cleaner manifested as angioedema. PubMed: On the temperature dependence of flammability limits of gases. PubMed: Sudden death involving inhalation of 1,1-difluoroethane (HFC-152a) with spray cleaner: three case reports. PubMed: Uptake and distribution of the abused inhalant 1,1-difluoroethane in the rat. PubMed: Reproductive and developmental toxicity of hydrofluorocarbons used as refrigerants. PubMed: Liquid-air partition coefficients of 1,1-difluoroethane (HFC152a), 1,1,1-trifluoroethane (HFC143a), 1,1,1,2-tetrafluoroethane (HFC134a), 1,1,1,2,2-pentafluoroethane (HFC125) and 1,1,1,3,3-pentafluoropropane (HFC245fa). PubMed: Comparison of gas-solid chromatography and MM2 force field molecular binding energies for greenhouse gases on a carbonaceous surface. PubMed: A validated method for the quantitation of 1,1-difluoroethane using a gas in equilibrium method of calibration. PubMed: Inhalant abuse of 1,1-difluoroethane (DFE) leading to heterotopic ossification: a case report. PubMed: Burning velocity measurements of nitrogen-containing compounds. PubMed: A study on flammability limits of fuel mixtures. PubMed: Hydrofluoric acid burn in a child from a compressed air duster. PubMed: Shock tube study of dissociation and relaxation in 1,1-difluoroethane and vinyl fluoride. PubMed: A motor vehicle accident fatality involving the inhalation of 1,1-difluoroethane. PubMed: Anomalous sorption of supercritical fluids on polymer thin films. PubMed: Ground and excited state dissociation dynamics of ionized 1,1-difluoroethene. PubMed: Extended Le Chatelier's formula for carbon dioxide dilution effect on flammability limits. PubMed: An investigation of the structure and bond rotational potential of some fluorinated ethanes by NMR spectroscopy of solutions in nematic liquid crystalline solvents. PubMed: Fatal cardiac arrhythmia after repeated exposure to 1,1-difluoroethane (DFE). PubMed: Headspace gas chromatographic method for the measurement of difluoroethane in blood. PubMed: An atmospheric pressure chemical ionization study of the positive and negative ion chemistry of the hydrofluorocarbons 1,1-difluoroethane (HFC-152a) and 1,1,1,2-tetrafluoroethane (HFC-134a) and of perfluoro-n-hexane (FC-72) in air plasma at atmospheric pressure. PubMed: Sudden death caused by 1,1-difluoroethane inhalation. PubMed: Hydrofluoric acid burn resulting from ignition of gas from a compressed air duster. PubMed: Combined ab initio/empirical approach for optimization of Lennard-Jones parameters for polar-neutral compounds. PubMed: Chlorodifluoroacetic acid fate and toxicity to the macrophytes Lemna gibba, Myriophyllum spicatum, and Myriophyllum sibiricum in aquatic microcosms. PubMed: Oral frostbite injury from intentional abuse of a fluorinated hydrocarbon. PubMed: Microwave Spectrum, Structure, and Nuclear Quadrupole Coupling Constants of 1-Bromo-1-fluoroethane. PubMed: Two traffic fatalities related to the use of difluoroethane. PubMed: Theoretical evaluation of two plausible routes for bioactivation of S-(1,1-difluoro-2,2-dihaloethyl)-L-cysteine conjugates: thiirane vs thionoacyl fluoride pathway. PubMed: Human reductive halothane metabolism in vitro is catalyzed by cytochrome P450 2A6 and 3A4. PubMed: Fluoroacetate-mediated toxicity of fluorinated ethanes. PubMed: NTP Renal Toxicity Studies of Selected Halogenated Ethanes Administered by Gavage to F344/N Rats. PubMed: Metabolism of 1-fluoro-1,1,2-trichloroethane, 1,2-dichloro-1,1-difluoroethane, and 1,1,1-trifluoro-2-chloroethane. PubMed: Improved method for mutagenicity testing of gaseous compounds by using a gas sampling bag. PubMed: Slow-binding inhibition of carboxylesterase and other serine hydrolases by chlorodifluoroacetaldehyde. PubMed: Metabolism and pharmacokinetics of selected halon replacement candidates. PubMed: Dominant role of cytochrome P-450 2E1 in human hepatic microsomal oxidation of the CFC-substitute 1,1,1,2-tetrafluoroethane. PubMed: Metabolism and toxicity of hydrochlorofluorocarbons: current knowledge and needs for the future. PubMed: Metabolism of the hydrochlorofluorocarbon 1,2-dichloro-1,1-difluoroethane. PubMed: Metabolism of 2-chloro-1,1-difluoroethene to glyoxylic and glycolic acid in rat hepatic microsomes. PubMed: A case of an accidental exposure to a veterinary insecticide product formulation. PubMed: Toxicological evaluation of hydrochlorofluorocarbon 142b.