hydrofluorocarbon 152A
1,1-difluoroethane
Identification
| Name | hydrofluorocarbon 152A |
| IUPAC | 1,1-difluoroethane |
| CAS Number | 75-37-6 |
| EINECS | 200-866-1 |
| FDA UNII | 0B1U8K2ME0 |
| Molecular Formula | C2 H4 F2 |
| Molecular Weight | 66.05068640 |
| MDL Number | MFCD00000449 |
| Nikkaji Number | J2.819C |
| Beilstein | 1696900 |
Regulatory
| DG SANTE Food Contact Materials | 1,1-difluoroethane |
| FDA Mainterm (IAUFC) | 75-37-6 ; 1,1-DIFLUOROETHANE |
Physical Properties
| Appearance | colorless gas (est) |
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | -117.00 °C. @ 760.00 mm Hg (est) |
| Boiling Point | -24.70 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure | 4550.000000 mmHg @ 25.00 °C. (est) |
| Vapor Density | 2.3 ( Air = 1 ) |
| Flash Point | -80.00 °F. TCC ( -62.00 °C. ) (est) |
| logP (o/w) | 0.750 |
| Soluble in | water, 3200 mg/L @ 21C (exp) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | propellants |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | oral-rat LDLo > 1500 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | inhalation-mouse LC50 977000 mg/m3/2H |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | propellants, aerating agents, and gas |
| Recommendation for hydrofluorocarbon 152A usage levels up to | not for fragrance use. |
| Recommendation for hydrofluorocarbon 152A flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
algofrene type 67
1,1-
difluoroethane
dymel 152
dymel 152A
ethane, 1,1-difluoro-
ethylene fluoride
ethylidene difluoride
ethylidene fluoride
FC 152A
fluorocarbon 152A
freon 152A
genetron 100
genetron 152A
halocarbon 152A
HFC 152A
HFC-152A
HSDB 5205
R 152A
refrigerant 152A
PubMed:
Blood and exhaled air can be used for biomonitoring of hydrofluorocarbon exposure.
PubMed:
Identification of volatiles by headspace gas chromatography with simultaneous flame ionization and mass spectrometric detection.
PubMed:
[In-situ measurement of background atmospheric HCFC-142b using GC-MS and GC-ECD method].
PubMed:
Evaluation of left ventricular function by bedside ultrasound in acute toxic myocarditis.
PubMed:
Greenhouse gas emissions for refrigerant choices in room air conditioner units.
PubMed:
Deaths involving 1,1-difluoroethane at the San Diego County Medical Examiner's Office.
PubMed:
Triboelectricity: macroscopic charge patterns formed by self-arraying ions on polymer surfaces.
PubMed:
Dusting right under our nose: difluoroethane abuse in the emergency department.
PubMed:
Uptake and disposition of 1,1-difluoroethane (HFC-152a) in humans.
PubMed:
Ethanol analysis by headspace gas chromatography with simultaneous flame-ionization and mass spectrometry detection.
PubMed:
Inhalant abuse of computer cleaner manifested as angioedema.
PubMed:
On the temperature dependence of flammability limits of gases.
PubMed:
Sudden death involving inhalation of 1,1-difluoroethane (HFC-152a) with spray cleaner: three case reports.
PubMed:
Uptake and distribution of the abused inhalant 1,1-difluoroethane in the rat.
PubMed:
Reproductive and developmental toxicity of hydrofluorocarbons used as refrigerants.
PubMed:
Liquid-air partition coefficients of 1,1-difluoroethane (HFC152a), 1,1,1-trifluoroethane (HFC143a), 1,1,1,2-tetrafluoroethane (HFC134a), 1,1,1,2,2-pentafluoroethane (HFC125) and 1,1,1,3,3-pentafluoropropane (HFC245fa).
PubMed:
Comparison of gas-solid chromatography and MM2 force field molecular binding energies for greenhouse gases on a carbonaceous surface.
PubMed:
A validated method for the quantitation of 1,1-difluoroethane using a gas in equilibrium method of calibration.
PubMed:
Inhalant abuse of 1,1-difluoroethane (DFE) leading to heterotopic ossification: a case report.
PubMed:
Burning velocity measurements of nitrogen-containing compounds.
PubMed:
A study on flammability limits of fuel mixtures.
PubMed:
Hydrofluoric acid burn in a child from a compressed air duster.
PubMed:
Shock tube study of dissociation and relaxation in 1,1-difluoroethane and vinyl fluoride.
PubMed:
A motor vehicle accident fatality involving the inhalation of 1,1-difluoroethane.
PubMed:
Anomalous sorption of supercritical fluids on polymer thin films.
PubMed:
Ground and excited state dissociation dynamics of ionized 1,1-difluoroethene.
PubMed:
Extended Le Chatelier's formula for carbon dioxide dilution effect on flammability limits.
PubMed:
An investigation of the structure and bond rotational potential of some fluorinated ethanes by NMR spectroscopy of solutions in nematic liquid crystalline solvents.
PubMed:
Fatal cardiac arrhythmia after repeated exposure to 1,1-difluoroethane (DFE).
PubMed:
Headspace gas chromatographic method for the measurement of difluoroethane in blood.
PubMed:
An atmospheric pressure chemical ionization study of the positive and negative ion chemistry of the hydrofluorocarbons 1,1-difluoroethane (HFC-152a) and 1,1,1,2-tetrafluoroethane (HFC-134a) and of perfluoro-n-hexane (FC-72) in air plasma at atmospheric pressure.
PubMed:
Sudden death caused by 1,1-difluoroethane inhalation.
PubMed:
Hydrofluoric acid burn resulting from ignition of gas from a compressed air duster.
PubMed:
Combined ab initio/empirical approach for optimization of Lennard-Jones parameters for polar-neutral compounds.
PubMed:
Chlorodifluoroacetic acid fate and toxicity to the macrophytes Lemna gibba, Myriophyllum spicatum, and Myriophyllum sibiricum in aquatic microcosms.
PubMed:
Oral frostbite injury from intentional abuse of a fluorinated hydrocarbon.
PubMed:
Microwave Spectrum, Structure, and Nuclear Quadrupole Coupling Constants of 1-Bromo-1-fluoroethane.
PubMed:
Two traffic fatalities related to the use of difluoroethane.
PubMed:
Theoretical evaluation of two plausible routes for bioactivation of S-(1,1-difluoro-2,2-dihaloethyl)-L-cysteine conjugates: thiirane vs thionoacyl fluoride pathway.
PubMed:
Human reductive halothane metabolism in vitro is catalyzed by cytochrome P450 2A6 and 3A4.
PubMed:
Fluoroacetate-mediated toxicity of fluorinated ethanes.
PubMed:
NTP Renal Toxicity Studies of Selected Halogenated Ethanes Administered by Gavage to F344/N Rats.
PubMed:
Metabolism of 1-fluoro-1,1,2-trichloroethane, 1,2-dichloro-1,1-difluoroethane, and 1,1,1-trifluoro-2-chloroethane.
PubMed:
Improved method for mutagenicity testing of gaseous compounds by using a gas sampling bag.
PubMed:
Slow-binding inhibition of carboxylesterase and other serine hydrolases by chlorodifluoroacetaldehyde.
PubMed:
Metabolism and pharmacokinetics of selected halon replacement candidates.
PubMed:
Dominant role of cytochrome P-450 2E1 in human hepatic microsomal oxidation of the CFC-substitute 1,1,1,2-tetrafluoroethane.
PubMed:
Metabolism and toxicity of hydrochlorofluorocarbons: current knowledge and needs for the future.
PubMed:
Metabolism of the hydrochlorofluorocarbon 1,2-dichloro-1,1-difluoroethane.
PubMed:
Metabolism of 2-chloro-1,1-difluoroethene to glyoxylic and glycolic acid in rat hepatic microsomes.
PubMed:
A case of an accidental exposure to a veterinary insecticide product formulation.
PubMed:
Toxicological evaluation of hydrochlorofluorocarbon 142b.