trimellitic acid

1,2,4-benzenetricarboxylic acid

CAS: 528-44-9 C9 H6 O6 MW: 210.14202000

Identification

Nametrimellitic acid
IUPACbenzene-1,2,4-tricarboxylic acid
CAS Number528-44-9
EINECS208-432-3
FDA UNII7NVY29MQ5F
Molecular FormulaC9 H6 O6
Molecular Weight210.14202000
MDL NumberMFCD00002470
Nikkaji NumberJ6.674E
Beilstein2214815
XlogP30.30 (est)

Regulatory

DG SANTE Food Contact Materialstrimellitic acid
FDA Mainterm (IAUFC)528-44-9 ; TRIMELLITIC ACID

Physical Properties

Assay 98.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 219.00 °C. @ 760.00 mm Hg
Boiling Point 505.51 °C. @ 760.00 mm Hg (est)
Flash Point 525.00 °F. TCC ( 273.60 °C. ) (est)
logP (o/w) 1.240 (est)
Soluble in water, 21000 mg/L @ 25 °C (exp)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityoral-mouse LD50 2500 mg/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorymonomer in epoxy resins for coatings
Recommendation for trimellitic acid usage levels up tonot for fragrance use.
Recommendation for trimellitic acid flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

1,2,4- benzene tricarboxylic acid benzene-1,2,4-tricarboxylic acid 1,2,4- benzenetricarboxylic acid 1,2,4- benzenetricarboxylicacid PubMed: Semiconductor Behavior of a Three-Dimensional Strontium-Based Metal-Organic Framework. PubMed: Separation of the isomers of benzene poly(carboxylic acid)s by quaternary ammonium salt via formation of deep eutectic solvents. PubMed: Biotechnological production of muconic acid: current status and future prospects. PubMed: Role of 2-hydroxyethyl methacrylate in the interaction of dental monomers with collagen studied by saturation transfer difference NMR. PubMed: Bismuth tri- and tetraarylcarboxylates: crystal structures, in situ X-ray diffraction, intermediates and luminescence. PubMed: Assembly and properties of transition-metal coordination polymers based on semi-rigid bis-pyridyl-bis-amide ligand: effect of polycarboxylates on the dimensionality. PubMed: Chronic administration of the selective P2X3, P2X2/3 receptor antagonist, A-317491, transiently attenuates cancer-induced bone pain in mice. PubMed: Simultaneous analysis of acidulants and preservatives in food samples by using capillary zone electrophoresis with indirect UV detection. PubMed: P2 receptor antagonists prevent synaptic failure and extracellular signal-regulated kinase 1/2 activation induced by oxygen and glucose deprivation in rat CA1 hippocampus in vitro. PubMed: CoMn2O4 spinel from a MOF: synthesis, structure and magnetic studies. PubMed: Effect of self-adhesive resin cement and tribochemical treatment on bond strength to zirconia. PubMed: Perfluorosulfonic acid membrane catalysts for optical sensing of anhydrides in the gas phase. PubMed: Design of a new dental adhesive--effect of a water-soluble sodium acylphosphine oxide with crown ether on adhesion to dental hard tissues. PubMed: Determining organic impurities in mother liquors from oxidative terephthalic acid synthesis by microemulsion electrokinetic chromatography. PubMed: Sample stacking for determination of aromatic acid impurities by microemulsion electrokinetic chromatography. PubMed: Complexation and determination of palladium (II) ion with para-Cl-phenylazo-R-acid spectrophotometrically. PubMed: Role of p38 MAPK in the selective release of IL-8 induced by chemical allergen in naive THp-1 cells. PubMed: Determination of common inorganic anions and cations by non-suppressed ion chromatography with column switching. PubMed: Effect of solvent type on the degradation of 4-MET. PubMed: CCR4 and CCR10 ligands play additive roles in mouse contact hypersensitivity. PubMed: Activation of urothelial transient receptor potential vanilloid 4 by 4alpha-phorbol 12,13-didecanoate contributes to altered bladder reflexes in the rat. PubMed: Analysis of chemical interaction of 4-MET with hydroxyapatite using XPS. PubMed: Biocompatibility and drug release behavior of spontaneously formed phospholipid polymer hydrogels. PubMed: Asymmetry induction by cooperative intermolecular hydrogen bonds in surface-anchored layers of achiral molecules. PubMed: Critical design features of phenyl carboxylate-containing polymer microbicides. PubMed: Simultaneous determination of inorganic anions and organic acids in amine solutions for sour gas treatment by capillary electrophoresis with indirect UV detection. PubMed: Design of extended surface-supported chiral metal-organic arrays comprising mononuclear iron centers. PubMed: Spontaneously forming hydrogel from water-soluble random- and block-type phospholipid polymers. PubMed: A-317491, a selective P2X3/P2X2/3 receptor antagonist, reverses inflammatory mechanical hyperalgesia through action at peripheral receptors in rats. PubMed: Effects of carboxyl groups on the adsorption behavior of low-molecular-weight substances on a stainless steel surface. PubMed: Migration of trimellitic acid from epoxy anhydride can coatings into foods. PubMed: Comparative study on adhesive performance of functional monomers. PubMed: Synthesis and antimicrobial activity of new adamantane derivatives III. PubMed: Application of capillary electrophoresis for organic acid analysis in herbal studies. PubMed: Conformational and quantum analysis of dental adhesive carboxylic acid and carboxylic acid anhydride monomers. PubMed: Analysis of low molecular weight organic acids in water with capillary zone electrophoresis employing indirect photometric detection. PubMed: Photoinduced electron-transfer reactions with quinolinic and trimellitic acid imides: experiments and spin density calculations(1) PubMed: Development of cellulose derivatives as novel enteric coating agents soluble at pH 3.5-4.5 and higher. PubMed: Acute autoimmune response in a case of pyromellitic acid dianhydride-induced hemorrhagic alveolitis. PubMed: [Dosimetry using pyromellitic acid and trimellitic acid. Part 1]. PubMed: Laser-Raman spectroscopic study of the adhesive interface; analysis between 4-META/MMA-TBB resin and bovine or human dentin. PubMed: Laser-Raman Spectroscopic study of the adhesive interface between 4-MET/MMA-TBB resin and hydroxyapatite or bovine enamel. PubMed: Construction, characteristics and application of a benzene-1,2,4-tricarboxylic acid selective electrode. PubMed: Specificity of the human IgE response to inhaled acid anhydrides. PubMed: Simultaneous determination of trimellitic anhydride and its trimellitic acid impurity by GC/FID. PubMed: Human antibodies against trimellityl proteins: comparison of specificities of IgG, IgA and IgE classes. PubMed: Asthma due to inhaled chemical agents--epoxy resin systems containing phthalic acid anhydride, trimellitic acid anhydride and triethylene tetramine. PubMed: Hydrolysis study of organic acid anhydrides by differential thermal analysis--II. Maleic anhydride and trimellitic anhydride.