trimellitic acid
1,2,4-benzenetricarboxylic acid
Identification
| Name | trimellitic acid |
| IUPAC | benzene-1,2,4-tricarboxylic acid |
| CAS Number | 528-44-9 |
| EINECS | 208-432-3 |
| FDA UNII | 7NVY29MQ5F |
| Molecular Formula | C9 H6 O6 |
| Molecular Weight | 210.14202000 |
| MDL Number | MFCD00002470 |
| Nikkaji Number | J6.674E |
| Beilstein | 2214815 |
| XlogP3 | 0.30 (est) |
Regulatory
| DG SANTE Food Contact Materials | trimellitic acid |
| FDA Mainterm (IAUFC) | 528-44-9 ; TRIMELLITIC ACID |
Physical Properties
| Assay | 98.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 219.00 °C. @ 760.00 mm Hg |
| Boiling Point | 505.51 °C. @ 760.00 mm Hg (est) |
| Flash Point | 525.00 °F. TCC ( 273.60 °C. ) (est) |
| logP (o/w) | 1.240 (est) |
| Soluble in | water, 21000 mg/L @ 25 °C (exp) |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | oral-mouse LD50 2500 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | monomer in epoxy resins for coatings |
| Recommendation for trimellitic acid usage levels up to | not for fragrance use. |
| Recommendation for trimellitic acid flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
1,2,4-
benzene tricarboxylic acid
benzene-1,2,4-tricarboxylic acid
1,2,4-
benzenetricarboxylic acid
1,2,4-
benzenetricarboxylicacid
PubMed:
Semiconductor Behavior of a Three-Dimensional Strontium-Based Metal-Organic Framework.
PubMed:
Separation of the isomers of benzene poly(carboxylic acid)s by quaternary ammonium salt via formation of deep eutectic solvents.
PubMed:
Biotechnological production of muconic acid: current status and future prospects.
PubMed:
Role of 2-hydroxyethyl methacrylate in the interaction of dental monomers with collagen studied by saturation transfer difference NMR.
PubMed:
Bismuth tri- and tetraarylcarboxylates: crystal structures, in situ X-ray diffraction, intermediates and luminescence.
PubMed:
Assembly and properties of transition-metal coordination polymers based on semi-rigid bis-pyridyl-bis-amide ligand: effect of polycarboxylates on the dimensionality.
PubMed:
Chronic administration of the selective P2X3, P2X2/3 receptor antagonist, A-317491, transiently attenuates cancer-induced bone pain in mice.
PubMed:
Simultaneous analysis of acidulants and preservatives in food samples by using capillary zone electrophoresis with indirect UV detection.
PubMed:
P2 receptor antagonists prevent synaptic failure and extracellular signal-regulated kinase 1/2 activation induced by oxygen and glucose deprivation in rat CA1 hippocampus in vitro.
PubMed:
CoMn2O4 spinel from a MOF: synthesis, structure and magnetic studies.
PubMed:
Effect of self-adhesive resin cement and tribochemical treatment on bond strength to zirconia.
PubMed:
Perfluorosulfonic acid membrane catalysts for optical sensing of anhydrides in the gas phase.
PubMed:
Design of a new dental adhesive--effect of a water-soluble sodium acylphosphine oxide with crown ether on adhesion to dental hard tissues.
PubMed:
Determining organic impurities in mother liquors from oxidative terephthalic acid synthesis by microemulsion electrokinetic chromatography.
PubMed:
Sample stacking for determination of aromatic acid impurities by microemulsion electrokinetic chromatography.
PubMed:
Complexation and determination of palladium (II) ion with para-Cl-phenylazo-R-acid spectrophotometrically.
PubMed:
Role of p38 MAPK in the selective release of IL-8 induced by chemical allergen in naive THp-1 cells.
PubMed:
Determination of common inorganic anions and cations by non-suppressed ion chromatography with column switching.
PubMed:
Effect of solvent type on the degradation of 4-MET.
PubMed:
CCR4 and CCR10 ligands play additive roles in mouse contact hypersensitivity.
PubMed:
Activation of urothelial transient receptor potential vanilloid 4 by 4alpha-phorbol 12,13-didecanoate contributes to altered bladder reflexes in the rat.
PubMed:
Analysis of chemical interaction of 4-MET with hydroxyapatite using XPS.
PubMed:
Biocompatibility and drug release behavior of spontaneously formed phospholipid polymer hydrogels.
PubMed:
Asymmetry induction by cooperative intermolecular hydrogen bonds in surface-anchored layers of achiral molecules.
PubMed:
Critical design features of phenyl carboxylate-containing polymer microbicides.
PubMed:
Simultaneous determination of inorganic anions and organic acids in amine solutions for sour gas treatment by capillary electrophoresis with indirect UV detection.
PubMed:
Design of extended surface-supported chiral metal-organic arrays comprising mononuclear iron centers.
PubMed:
Spontaneously forming hydrogel from water-soluble random- and block-type phospholipid polymers.
PubMed:
A-317491, a selective P2X3/P2X2/3 receptor antagonist, reverses inflammatory mechanical hyperalgesia through action at peripheral receptors in rats.
PubMed:
Effects of carboxyl groups on the adsorption behavior of low-molecular-weight substances on a stainless steel surface.
PubMed:
Migration of trimellitic acid from epoxy anhydride can coatings into foods.
PubMed:
Comparative study on adhesive performance of functional monomers.
PubMed:
Synthesis and antimicrobial activity of new adamantane derivatives III.
PubMed:
Application of capillary electrophoresis for organic acid analysis in herbal studies.
PubMed:
Conformational and quantum analysis of dental adhesive carboxylic acid and carboxylic acid anhydride monomers.
PubMed:
Analysis of low molecular weight organic acids in water with capillary zone electrophoresis employing indirect photometric detection.
PubMed:
Photoinduced electron-transfer reactions with quinolinic and trimellitic acid imides: experiments and spin density calculations(1)
PubMed:
Development of cellulose derivatives as novel enteric coating agents soluble at pH 3.5-4.5 and higher.
PubMed:
Acute autoimmune response in a case of pyromellitic acid dianhydride-induced hemorrhagic alveolitis.
PubMed:
[Dosimetry using pyromellitic acid and trimellitic acid. Part 1].
PubMed:
Laser-Raman spectroscopic study of the adhesive interface; analysis between 4-META/MMA-TBB resin and bovine or human dentin.
PubMed:
Laser-Raman Spectroscopic study of the adhesive interface between 4-MET/MMA-TBB resin and hydroxyapatite or bovine enamel.
PubMed:
Construction, characteristics and application of a benzene-1,2,4-tricarboxylic acid selective electrode.
PubMed:
Specificity of the human IgE response to inhaled acid anhydrides.
PubMed:
Simultaneous determination of trimellitic anhydride and its trimellitic acid impurity by GC/FID.
PubMed:
Human antibodies against trimellityl proteins: comparison of specificities of IgG, IgA and IgE classes.
PubMed:
Asthma due to inhaled chemical agents--epoxy resin systems containing phthalic acid anhydride, trimellitic acid anhydride and triethylene tetramine.
PubMed:
Hydrolysis study of organic acid anhydrides by differential thermal analysis--II. Maleic anhydride and trimellitic anhydride.