1,2-octane diol

caprylyl glycol

CAS: 1117-86-8 C8 H18 O2 MW: 146.22986000

Identification

Name1,2-octane diol
IUPACoctane-1,2-diol
CAS Number1117-86-8
EINECS214-254-7
FDA UNII00YIU5438U
Molecular FormulaC8 H18 O2
Molecular Weight146.22986000
MDL NumberMFCD00010738
Nikkaji NumberJ103.154F
Beilstein1719619
XlogP31.80 (est)

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 36.00 to 38.00 °C. @ 760.00 mm Hg
Boiling Point 243.00 to 244.00 °C. @ 760.00 mm Hg (est), 131.00 to 133.00 °C. @ 10.00 mm Hg
Vapor Pressure 0.006000 mmHg @ 25.00 °C. (est)
Flash Point 228.00 °F. TCC ( 109.10 °C. ) (est)
logP (o/w) 1.539 (est)
Soluble in alcohol
Insoluble in water

Cosmetic Information

CosIngcosmetic data
Cosmetic Useshair conditioning

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorycosmetic agents
Recommendation for 1,2-octane diol usage levels up tonot for fragrance use.
Recommendation for 1,2-octane diol flavor usage levels up tonot for flavor use.

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Symrise AG

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Vigon International

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Manufacturer and supplier of high quality flavor and fragrance ingredients.

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Potential Uses

antistatic agents emollients humectants

Natural Occurrence

not found in nature

Synonyms

capryl glycol caprylyl glycol 1,2- dihydroxyoctane hydrolite 8 (Symrise) hydrolite CG (Symrise) 1,2- octane diol octane-1,2-diol 1,2- octanediol 1,2- octylene glycol viguard CEHG PubMed: Demodex folliculitis presenting as periocular vesiculopustular rash. PubMed: Catalytic deoxydehydration of diols to olefins by using a bulky cyclopentadiene-based trioxorhenium catalyst. PubMed: Safety assessment of 1,2-glycols as used in cosmetics. PubMed: 1,2-Octanediol, a novel surfactant, for treating head louse infestation: identification of activity, formulation, and randomised, controlled trials. PubMed: The influence of alkane chain length on the skin irritation potential of 1,2-alkanediols. PubMed: New insights into silica-based NMR "chromatography". PubMed: Preparation of (S)-1-Halo-2-octanols Using Ionic Liquids and Biocatalysts. PubMed: Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol. PubMed: [BMIM][PF(6)] promotes the synthesis of halohydrin esters from diols using potassium halides. PubMed: Octanediol treatment of glutaraldehyde fixed bovine pericardium: evidence of anticalcification efficacy in the subcutaneous rat model. PubMed: Purification, characterization, and gene cloning of glycerol dehydrogenase from Hansenula ofunaensis, and its expression for production of optically active diol. PubMed: Spreading on and penetration into thin, permeable print media: application to ink-jet printing. PubMed: Treatment of bioprosthetic heart valve tissue with long chain alcohol solution to lower calcification potential. PubMed: Organic modifiers for the separation of organic acids and bases by liquid chromatography. PubMed: Microemulsions for topical delivery of 8-methoxsalen. PubMed: Effects of alcohols and diols on the phase behaviour of quaternary systems. PubMed: Explorations of alkyl polyols as "class I" organic modifiers to adjust selectivity in micellar electrokinetic capillary chromatography. PubMed: Metabolic activation of olefins. Conversion of 1-octene to a putative reactive intermediate 1-octen-3-one: an alternative pathway to epoxidation. PubMed: Treatment of pediculosis capitis: a critical appraisal of the current literature. PubMed: Head lice. Dimeticone is the pediculicide of choice. PubMed: Prevention of head louse infestation: a randomised, double-blind, cross-over study of a novel concept product, 1% 1,2-octanediol spray versus placebo.