1,5-pentane diol

pentamethylene glycol

CAS: 111-29-5 C5 H12 O2 MW: 104.14904000

Identification

Name1,5-pentane diol
IUPACpentane-1,5-diol
CAS Number111-29-5
EINECS203-854-4
FDA UNII07UXZ0SCST
Molecular FormulaC5 H12 O2
Molecular Weight104.14904000
MDL NumberMFCD00002978
Nikkaji NumberJ5.107A
Beilstein1560130

Regulatory

Physical Properties

Appearance colorless clear viscous liquid (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 0.99400 @ 25.00 °C.
Refractive Index 1.45000 @ 20.00 °C.
Melting Point -16.00 °C. @ 760.00 mm Hg
Boiling Point 238.00 to 239.00 °C. @ 760.00 mm Hg
Vapor Pressure 0.003900 mmHg @ 25.00 °C.
Flash Point 265.00 °F. TCC ( 129.44 °C. )
logP (o/w) -0.599 (est)
Soluble in alcohol

Cosmetic Information

CosIngcosmetic data
Cosmetic Usessolvents

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityoral-rabbit LD50 6300 mg/kg
Dermal Toxicityskin-rabbit LD50 > 20 ml/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorysolvents
Recommendation for 1,5-pentane diol usage levels up tonot for fragrance use.
Recommendation for 1,5-pentane diol flavor usage levels up tonot for flavor use.

BOC Sciences

Best of Chemicals Supplier

Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...

View All Website 1-631-485-4226 account@bocsci.com

Penta International Corporation

Chemistry innovation

At Penta, our products and services help businesses do business better.

View All Website (973) 740-2300 lisaa@pentamfg.com

TCI AMERICA

Moving Your Chemistry Forward

We continuously strive to advance our technology.

View All Website 1-800-423-8616 Sales-US@TCIchemicals.com;

Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

1,5- dihydroxypentane pentamethylene glycol 1,5- pentamethylene glycol alpha,omega- pentane diol pentane-1,5-diol 1,5- pentanediol alpha,omega- pentanediol 1,5- pentylene glycol PubMed: Contribution of liver alcohol dehydrogenase to metabolism of alcohols in rats. PubMed: Excess enthalpies of mixing, effect of temperature and composition on the density, and viscosity and thermodynamic properties of binary systems of {ammonium-based ionic liquid + alkanediol}. PubMed: Enzymatic production of 5-aminovalerate from L-lysine using L-lysine monooxygenase and 5-aminovaleramide amidohydrolase. PubMed: Tetrabutylammonium bromide (TBABr)-based deep eutectic solvents (DESs) and their physical properties. PubMed: A comparative ultrasonic relaxation study of lower vicinal and terminal alkanediols at 298.15 K in relation to their molecular structure and hydrogen bonding. PubMed: 1,3,5-Tri-p-tolyl-pentane-1,5-diol. PubMed: Preliminary crystallographic analysis of a cruciferin protein from seeds of Moringa oleifera. PubMed: Isolation, structure determination, and antiaging effects of 2,3-pentanediol from endophytic fungus of Curcuma amada and docking studies. PubMed: Molybdenum-catalyzed deoxydehydration of vicinal diols. PubMed: Aqueous phase hydrogenation of levulinic acid to 1,4-pentanediol. PubMed: Safety assessment and biological effects of a new cold processed SilEmulsion for dermatological purpose. PubMed: Phase-diagram-guided method for growth of a large crystal of glycoside hydrolase family 45 inverting cellulase suitable for neutron structural analysis. PubMed: Cubic and sponge phases in ether lipid-solvent-water ternary systems: phase behavior and NMR characterization. PubMed: Controlled synthesis of ultrathin lamellar Eu(2)O(3) nanocrystals: self-assembly of 1D nanowires to 2D nanosheets. PubMed: In vivo study of an instantly formed lipid-water cubic phase formulation for efficient topical delivery of aminolevulinic acid and methyl-aminolevulinate. PubMed: Metabolic engineering of Escherichia coli for the production of 5-aminovalerate and glutarate as C5 platform chemicals. PubMed: Catalyst-controlled reversal of chemoselectivity in acylation of 2-aminopentane-1,5-diol derivatives. PubMed: Highly crosslinked polymeric monoliths for reversed-phase capillary liquid chromatography of small molecules. PubMed: Synthesis of high molecular weight polyesters via in vacuo dehydrogenation polymerization of diols. PubMed: Theoretical calculation of the OH vibrational overtone spectra of 1,5-pentanediol and 1,6-hexanediol. PubMed: A Fast Degrading Odd-Odd Aliphatic Polyester-5,7 Made by Condensation Polymerization for Biomedical Applications. PubMed: The preparation of 3-substituted-1,5-dibromopentanes as precursors to heteracyclohexanes. PubMed: Direct catalytic conversion of furfural to 1,5-pentanediol by hydrogenolysis of the furan ring under mild conditions over Pt/Co2AlO4 catalyst. PubMed: The size control of silver nanocrystals with different polyols and its application to low-reflection coating materials. PubMed: Influence of polyols on the formation of iron oxide nanoparticles in solvothermal system. PubMed: A practical total synthesis of (+)-spirolaxine methyl ether. PubMed: Internally protected amino sugar equivalents from enantiopure 1,2-oxazines: synthesis of variably configured carbohydrates with C-branched amino sugar units. PubMed: Allergic contact dermatitis to propyl gallate and pentylene glycol in an emollient cream. PubMed: Lipase-catalyzed regioselective monoacetylation of unsymmetrical 1,5-primary diols. PubMed: Improved synthesis of three methyl-branched pheromone components produced by the female lichen moth. PubMed: Bridged oligonucleotides as molecular probes for investigation of enzyme-substrate interaction and allele-specific analysis of DNA. PubMed: Reactivity of poly-alcohols towards OH, NO3 and SO4- in aqueous solution. PubMed: In vitro activity of chlorhexidine and pentane-1,5-diol and their combination on Candida albicans, Staphylococcus aureus and Propionibacterium acnes. PubMed: 1,4-Butanediol content of aqua dots children's craft toy beads. PubMed: Therapeutic effect of 1,5-pentanediol for herpes simplex labialis: a randomized, double-blind, placebo-controlled clinical trial. PubMed: The shape evolution of gold seeds and gold@silver core-shell nanostructures. PubMed: Experimental stroke protection induced by 4-hydroxybenzyl alcohol is cancelled by bacitracin. PubMed: Transferable force field for alcohols and polyalcohols. PubMed: Chemoselective hydrogenolysis of tetrahydrofurfuryl alcohol to 1,5-pentanediol. PubMed: Effect of pentane-1,5-diol and propane-1,2-diol on percutaneous absorption of terbinafine. PubMed: Enantioselective syntheses of both enantiomers of noranabasamine. PubMed: Thermal properties and mixing state of diol-water mixtures studied by calorimetry, large-angle X-ray scattering, and NMR relaxation. PubMed: A comparison of pentane-1,5-diol to other diols for use in dermatology. PubMed: Synthesis of phosphate monomers and bonding to dentin: esterification methods and use of phosphorus pentoxide. PubMed: Allergic contact dermatitis to pentylene glycol in a cosmetic cream. PubMed: [Spectral studies on liquid crystal photoalignment film of photosensitive monomer with fluorinated groups]. PubMed: Polyhedral gold nanocrystals with O h symmetry: from octahedra to cubes. PubMed: Treatment of atopic dermatitis with 1% hydrocortisone and 25% pentane-1,5-diol: effect on Staphylococcus aureus. PubMed: Thermotropic properties of organic nanocrystals embedded in ultrasmall crystallization chambers. PubMed: MD simulations of the binding of alcohols and diols by a calixarene in water: connections between microscopic and macroscopic properties. PubMed: Pentane-1,5-diol as a percutaneous absorption enhancer. PubMed: Total synthesis of the epoxy isoprostane phospholipids PEIPC and PECPC. PubMed: The in vitro activity of pentane-1,5-diol against aerobic bacteria. A new antimicrobial agent for topical usage? PubMed: Removal of lipopolysaccharides from protein-lipopolysaccharide complexes by nonflammable solvents. PubMed: Characterization of European wine glycerol: stable carbon isotope approach. PubMed: Improved assay for determination of busulfan by liquid chromatography using postcolumn photolysis. PubMed: Simple synthesis of beta-D-glycopyranosides using beta-glycosidase from almonds. PubMed: Allergic contact dermatitis from pentylene glycol in an emollient cream, with possible co-sensitization to resveratrol. PubMed: Continuous monitoring of prostatic acid phosphatase using self-indicating substrates. PubMed: Effects of aldehydes and methods of cross-linking on properties of calcium alginate microspheres prepared by emulsification. PubMed: Stereocontrolled total synthesis of the Stemona alkaloid (-)-stenine. PubMed: Volumes of aqueous alcohols, ethers, and ketones to T = 523 K and p = 28 MPa. PubMed: Aerobic and anaerobic metabolism of glutaraldehyde in a river water-sediment system. PubMed: New synthesis of serricornin, the female sex pheromone of the cigarette beetle. PubMed: Ecotoxicology of glutaraldehyde: review of environmental fate and effects studies. PubMed: Determination of leachable components from four commercial dental composites by gas and liquid chromatography/mass spectrometry. PubMed: On protein solubility in organic solvent. PubMed: The effect of pH and temperature on the stability and enzymatic activity of prostatic acid phosphatase. Studies on the optimization of a continuous monitored determination of acid phosphatase, II. PubMed: Effect of ascorbic acid on the metabolism of N-nitrosopiperidine. PubMed: Protection of CGS 10078B against ouabain-induced arrhythmia in the cat. PubMed: [Synthesis of propenol and pentanediol derivatives]. PubMed: Synthesis and antitumor effect of new biological alkylating agents, isethionic acid esters. PubMed: Mutagenicity and alpha-hydroxylation of N-nitrosopyrrolidine and N-nitrosopiperidine: a possible correlation. PubMed: The antimycotic activity in vitro of five diols. PubMed: Permeability of dog lung endothelium to sodium, diols, amides, and water. PubMed: Inhibition of bovine hepatic fructose-1,6-diphosphatase by substrate analogs. PubMed: Action of gamma radiation on liquid 1,5-pentanediol. PubMed: Preparation of dihydropyran delta-hydroxyvaleraldehyde and 1,5-pentanediol from tetrahydrofurfuryl alcohol.