danthron

9,10- anthracenedione, 1,8-dihydroxy- anthraquinone, 1,8-dihydroxy- antrapurol bancon chrysazin chrysazine criasazin danivac danthrone dantron dantrone dantronum dianthon diaquone 9,10- dihydro-1,8-dihydroxy-9,10-dioxoanthracene 1,8- dihydroanthraquinone 1,8- dihydroxy-9,10-anthracenedione, 9CI 1,8- dihydroxy-9,10-anthraquinone 1,8- dihydroxy-9,10-dihydroanthracene-9,10-dione 1,8- dihydroxyanthra-9,10-quinone 1,8- dihydroxyanthracene-9,10-dione 1,8- dihydroxyanthrachinon 1,8- dihydroxyanthraquinone dionone 1,8- dioxyanthraquinone dorbane dorbanex dorbantyl duolax istizin laxanorm laxanthreen laxapur laxipur laxipurin neokutin S 1,8-bis( oxidanyl)anthracene-9,10-dione pastomin prugol roydan scatron D 1,4,5,8- tetroxyantraquinone zwitsalax PubMed: In vitro glucuronidation of five rhubarb anthraquinones by intestinal and liver microsomes from humans and rats. PubMed: Anthraquinones quinizarin and danthron unwind negatively supercoiled DNA and lengthen linear DNA. PubMed: Danthron activates AMP-activated protein kinase and regulates lipid and glucose metabolism in vitro. PubMed: Spectroscopic and in silico evaluation of interaction of DNA with six anthraquinone derivatives. PubMed: A new dibenz[b,e]oxepine derivative, 1-hydroxy-10-methoxy-dibenz[b,e]oxepin-6,11-dione, from a marine-derived fungus, Beauveria bassiana TPU942. PubMed: Toxicology study of senna (CAS No. 8013-11-4) in C57BL/6NTAC Mice and toxicology and carcinogenesis study of senna in genetically modified C3B6.129F1/Tac-Trp53tm1Brd haploinsufficient mice (Feed Studies). PubMed: Colorimetric and fluorescence sensing of Cu2+ in water using 1,8-dihydroxyanthraquinone-β-cyclodextrin complex with the assistance of ammonia. PubMed: Danthron triggers ROS and mitochondria-mediated apoptotic death in C6 rat glioma cells through caspase cascades, apoptosis-inducing factor and endonuclease G multiple signaling. PubMed: Bioguided Fractionation Shows Cassia alata Extract to Inhibit Staphylococcus epidermidis and Pseudomonas aeruginosa Growth and Biofilm Formation. PubMed: DNA-binding, DNA cleavage and cytotoxicity studies of two anthraquinone derivatives. PubMed: Comparison of dispersive liquid-liquid microextraction based on organic solvent and ionic liquid combined with high-performance liquid chromatography for the analysis of emodin and its metabolites in urine samples. PubMed: Danthron. PubMed: Danthron inhibits murine WEHI-3 cells in vivo, and enhances macrophage phagocytosis and natural killer cell cytotoxic activity in leukemic mice. PubMed: DNA-binding study of anthraquinone derivatives using chemometrics methods. PubMed: In vitro genotoxicity of danthron and its potential mechanism. PubMed: Laxatives or methylnaltrexone for the management of constipation in palliative care patients. PubMed: Danthron, an anthraquinone derivative, induces DNA damage and caspase cascades-mediated apoptosis in SNU-1 human gastric cancer cells through mitochondrial permeability transition pores and Bax-triggered pathways. PubMed: Danthron functions as a retinoic X receptor antagonist by stabilizing tetramers of the receptor. PubMed: Synchrotron radiation linear dichroism (SRLD) investigation of the electronic transitions of quinizarin, chrysazin, and anthrarufin. PubMed: Danthron induces DNA damage and inhibits DNA repair gene expressions in GBM 8401 human brain glioblastoma multiforms cells. PubMed: Anthraquinones danthron and quinizarin exert antiproliferative and antimetastatic activity on murine B16-F10 melanoma cells. PubMed: Danthron inhibits the migration and invasion of human brain glioblastoma multiforme cells through the inhibition of mRNA expression of focal adhesion kinase, Rho kinases-1 and metalloproteinase-9. PubMed: Danthron induced apoptosis through mitochondria- and caspase-3-dependent pathways in human brain glioblastoma multiforms GBM 8401 cells. PubMed: Aloe-emodin-induced DNA fragmentation in the mouse in vivo comet assay. PubMed: Structure-activity relationships of anthraquinones on the suppression of DNA-binding activity of the aryl hydrocarbon receptor induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin. PubMed: Dissociative photoionization mechanism of 1,8-dihydroxyanthraquinone: an experimental and theoretical study. PubMed: Study of interactions of anthraquinones with DNA using ethidium bromide as a fluorescence probe. PubMed: Anthranoid laxatives influence the absorption of poorly permeable drugs in human intestinal cell culture model (Caco-2). PubMed: Laxatives for the management of constipation in palliative care patients. PubMed: Defensive components in insect eggs: are anthraquinones produced during egg development? PubMed: Reactivity of aromatic amines with triplet 1,8-dihydroxyanthraquinone: a laser flash photolysis study. PubMed: [Toxic effects of 1,8-dihydroxyanthraquinone on Daphnia magna]. PubMed: Electrochemical studies of danthron and the DNA-danthron interaction. PubMed: Danthron (1,8-dihydroxyanthraquinone). PubMed: Danthron inhibits the neurotoxicity induced by various compounds causing oxidative damages including beta-amyloid (25-35) in primary cortical cultures. PubMed: Danthron (1,8-dihydroxyanthraquinone). PubMed: Emodin isolated from Cassia obtusifolia (Leguminosae) seed shows larvicidal activity against three mosquito species. PubMed: Factors influencing constipation in advanced cancer patients: a prospective study of opioid dose, dantron dose and physical functioning. PubMed: [Studies on the chemical constituents of Shiraia bambusicola]. PubMed: Cytotoxicity of natural hydroxyanthraquinones: role of oxidative stress. PubMed: Antimutagenic effects of black tea (World Blend) and its two active polyphenols theaflavins and thearubigins in Salmonella assays. PubMed: Enrichment of iron(III), cobalt(II), nickel(II), and copper(II) by solid-phase extraction with 1,8-dihydroxyanthraquinone anchored to silica gel before their determination by flame atomic absorption spectrometry. PubMed: Bryoanthrathiophene, a new antiangiogenic constituent from the bryozoan Watersipora subtorquata (d'Orbigny, 1852). PubMed: Cytotoxicity of rhein, the active metabolite of sennoside laxatives, is reduced by multidrug resistance-associated protein 1. PubMed: Sequence-specific DNA damage induced by carcinogenic danthron and anthraquinone in the presence of Cu(II), cytochrome P450 reductase and NADPH. PubMed: Adverse effects of laxatives. PubMed: Inhibition of cell growth in culture by quinones. PubMed: The irritancy of anthralin is inhibited by repeat applications of a subirritant concentration. PubMed: Antimutagenic effects of centchroman--a contraceptive and a candidate drug for breast cancer in multiple mutational assays. PubMed: Laxative drug products for over-the-counter human use. Food and Drug Administration, HHS. Final rule. PubMed: Anthraquinone cytotoxicity and apoptosis in primary cultures of rat hepatocytes. PubMed: Occurrence of emodin, chrysophanol and physcion in vegetables, herbs and liquors. Genotoxicity and anti-genotoxicity of the anthraquinones and of the whole plants. PubMed: Characterization of the genotoxicity of anthraquinones in mammalian cells. PubMed: Factors affecting the genotoxic potency ranking of natural anthraquinones in mammalian cell culture systems. PubMed: Enhancement of cell proliferation and prostaglandin biosynthesis by 1,8-dihydroxyanthraquinone in the rat large intestine. PubMed: Genotoxicity of the laxative drug components emodin, aloe-emodin and danthron in mammalian cells: topoisomerase II mediated? PubMed: Inactivation of mouse epidermal 12-lipoxygenase by anthralin--implications for the role of oxygen radicals. PubMed: Biotransformation of benzo[a]pyrene and other polycyclic aromatic hydrocarbons and heterocyclic analogs by several green algae and other algal species under gold and white light. PubMed: OTC pharmaceuticals and genotoxicity testing: the paracetamol, anthraquinone, and griseofulvin cases. PubMed: Effects of long-term treatment with anthranoids and sodium picosulphate on the contents of vasoactive intestinal polypeptide, somatostatin and substance P in the rat colon. PubMed: Cell proliferation induced by laxatives and related compounds in the rat intestine. PubMed: Toxicity of structurally related anthraquinones and anthrones to mammalian cells in vitro. PubMed: Promoting and synergistic effects of chrysazin on 1,2-dimethylhydrazine-induced carcinogenesis in male ICR/CD-1 mice. PubMed: Adverse effects of drugs used in the management of constipation and diarrhoea. PubMed: Analytics of senna drugs with regard to the toxicological discussion of anthranoids. PubMed: Light and electron-microscopic changes in the colon of the guinea pig after treatment with anthranoid and non-anthranoid laxatives. PubMed: Chronic sennoside treatment does not cause habituation and secondary hyperaldosteronism in rats. PubMed: Effects of long-term sennoside treatment on in vitro motility of rat colon. PubMed: A note on the complex metabolism of danthron infused into the rat. PubMed: Rhein and aloe-emodin kinetics from senna laxatives in man. PubMed: Pharmacokinetic-metabolic studies with 14C-aloe emodin after oral administration to male and female rats. PubMed: A rapid high-performance thin-layer chromatographic urine screen for laxative abuse. PubMed: Down-regulation of epidermal growth factor receptors by dithranol. PubMed: Laxative-induced contact dermatitis. PubMed: Inhibition of human monocyte functions by anthralin. PubMed: Effects of long-term laxative treatment on neuropeptides in rat mesenteric vessels and caecum. PubMed: Mutagenicity of substituted anthraquinones in the Ames/Salmonella microsome system. PubMed: Radical-mediated modification of deoxyguanine and deoxyribose by luteoskyrin and related anthraquinones. PubMed: Dithranol-induced down-regulation of 12(S)-hydroxyeicosatetraenoic acid [12(S)-HETE] receptors in a human epidermal cell line. PubMed: Spectroscopic studies of cutaneous photosensitizing agents--XV. Anthralin and its oxidation product 1,8-dihydroxyanthraquinone. PubMed: Effects of long-term laxative treatment on rat mesenteric resistance vessel responses in vitro. PubMed: Hydroxyanthraquinones as tumor promoters: enhancement of malignant transformation of C3H mouse fibroblasts and growth stimulation of primary rat hepatocytes. PubMed: Resistance of myenteric neurons in the rat's colon to depletion by 1,8-dihydroxyanthraquinone. PubMed: Dantron (chrysazin; 1,8-dihydroxyanthraquinone) PubMed: Relative metabolism of quinones to semiquinone radicals in xanthine oxidase system. PubMed: Normal-phase and reversed-phase liquid chromatographic techniques for the determination of dithranol and its degradation products. PubMed: Anthraquinone laxatives and human cancer: an association in one case. PubMed: Anthralin, a non-phorbol tumor promoter, fails to inhibit metabolic cooperation in mutant human fibroblasts, but inhibits phytohemagglutinin-induced lymphocyte blastogenesis in vitro. PubMed: Screening procedure for stimulant laxatives in urine using high-performance liquid chromatography with diode array detection. PubMed: Effects of withdrawal of co-danthramer on use of laxatives in a district general hospital. PubMed: Pigmentation of kidneys and lymph nodes of mesocolon in rats fed diets containing the laxative danthron. PubMed: Danthron alarm, FDA response: crucial OTC drug control. PubMed: Laxatives: replacing danthron. PubMed: Melanosis coli. A consequence of anthraquinone-induced apoptosis of colonic epithelial cells. PubMed: Inclusion complex formation of 1,8-dihydroxyanthraquinone with cyclodextrins in aqueous solution and in solid state. PubMed: Oxidation of antipsoriatic 10-acyldithranol derivatives and dithranol to 1,8-dihydroxyanthraquinone. PubMed: Patch testing with dithranol and its degradation products. PubMed: Long-term mucosal alterations by sennosides and related compounds. PubMed: Anthraquinone laxatives: metabolism and transport of danthron and rhein in the rat small and large intestine in vitro. PubMed: New aspects on the metabolism of the sennosides. PubMed: [Reactions and interactions of drugs according to "Drug Reactions and Interactions" by P.F. D'Arcy]. PubMed: Studies on laxatives: biliary and urinary excretion in rats given danthron by intravenous infusion or gastric intubation. PubMed: Anthralin stability in various vehicles. PubMed: [Danthron prohibition]. PubMed: The release and percutaneous permeation of anthralin products, using clinically involved and uninvolved psoriatic skin. PubMed: [Stability of cignolin (dithranol) in ointments containing tar with and without the addition of salicylic acid. Oxidation to danthron and dithranol dimer]. PubMed: [Mode of action of anthraquinone laxatives on the rat]. PubMed: The detection of laxative abuse. PubMed: Biotransformation of the carcinogen chrysazin by NADPH-microsome system. PubMed: Anthralin (1,8-dihydroxyanthrone) is a potent inhibitor of leukotriene production and LTB4-omega oxidation by human neutrophils. PubMed: Carcinogenicity of chrysazin in large intestine and liver of mice. PubMed: Acceleration of large intestine transit time in rats by sennosides and related compounds. PubMed: Induction of intestinal tumours in rats by chrysazin. PubMed: Comparative physiological disposition of some anthraquinone glycosides and aglycones. PubMed: Multifunctional inhibition by anthralin in nonstimulated and chemotactic factor stimulated human neutrophils. PubMed: [The study of the synthesis of the antineoplastic agent DHAQ]. PubMed: Inhibition of the mutagenicity of bay-region diol-epoxides of polycyclic aromatic hydrocarbons by tannic acid, hydroxylated anthraquinones and hydroxylated cinnamic acid derivatives. PubMed: Antirespiratory and antiproliferative activity of anthralin in cultured human keratinocytes. PubMed: Experimental contribution to the dithranol-brown problem. PubMed: Ultrastructure of mouse intestinal mucosa and changes observed after long term anthraquinone administration. PubMed: A cutaneous complication of Dorbanex therapy. PubMed: Laxative eruption. PubMed: Mutagenicity of quinones: pathways of metabolic activation and detoxification. PubMed: A cutaneous complication of Dorbanex therapy. PubMed: Anthralin inhibition of mouse epidermal arachidonic acid lipoxygenase in vitro. PubMed: Effect of indomethacin on aloin and 1,8 dioxianthraquinone-induced production of prostaglandins in rat isolated colon. PubMed: [Side effects of anthralin and its 2 main impurities on healthy skin]. PubMed: [Colon cleansing: a comparative study]. PubMed: Constipation in long-stay elderly patients: its treatment and prevention by lactulose, poloxalkol-dihydroxyanthroquinolone and phosphate enemas. PubMed: [Perianal toxic contact dermatitis after use of the laxative Dorbantyl]. PubMed: On the stability of some antipsoriatic active anthralin (dithranol) derivatives. PubMed: Inhibition of DNA replication and repair by anthralin or danthron in cultured human cells. PubMed: Mutagenicity of anthraquinone and hydroxylated anthraquinones in the Ames/Salmonella microsome system. PubMed: Inhibition of DNA replication and repair cultured humans cells by anthralin or danthron. PubMed: Influence of 1,8-dihydroxyanthraquinone and loperamide on the paracellular permeability across colonic mucosa. PubMed: A screening method for establishing laxative abuse. PubMed: [Clastogenic action of an anthraquinone compound on human lymphocytes]. PubMed: [Tienilic acid as a likely cause of "auto immune" active hepatitis (author's transl)]. PubMed: Danthron induced melanosis coli in the guinea pig. PubMed: Acute mouse and chronic dog toxicity studies of danthron, dioctyl sodium sulfosuccinate, poloxalkol and combinations. PubMed: Possible hepatotoxicity of Doxidan. PubMed: Danthron/poloxalkol and placebo in puerperal constipation. PubMed: [An interesting drug for the treatment of constipation: the association of calcium pantothenate and danthron]. PubMed: [Clinical trials of treatment of chronic constipation with a surface-active and hydrotropic agent in oral administration (dioctyl sodium sulfosuccinate with danthron). 64 cases, 41 of these assembled in a table]. PubMed: [Clinical trial of a combination: calcium pantothenate-danthron in 28 cases of constipation of various etiologies]. PubMed: INFLUENCE OF AN ORAL PERISTALTIC STIMULANT, DANTHRON, ON THE PHENOLSULPHONPHTHALEIN EXCRETION TEST. PubMed: Treatment of chronic functional constipation with dioctyl sodium sulfosuccinate and danthron. PubMed: Peristalticstimulating and fecal-hydrating properties of dioctyl sodium sulfosuccinate, danthron, and cascara extracts in the mouse and rat. PubMed: Use of doxinate with danthron as withdrawal therapy in the treatment of chronic functional constipation.