12-hydroxystearic acid
octadecanoic acid, 12-hydroxy-
Identification
| Name | 12-hydroxystearic acid |
| IUPAC | 12-hydroxyoctadecanoic acid |
| CAS Number | 106-14-9 |
| EINECS | 203-366-1 |
| FDA UNII | 933ANU3H2S |
| Molecular Formula | C18 H36 O3 |
| Molecular Weight | 300.48252000 |
| MDL Number | MFCD00004592 |
| Nikkaji Number | J48.641H |
| Beilstein | 1726730 |
| XlogP3 | 6.50 (est) |
Regulatory
| DG SANTE Food Contact Materials | 12-hydroxystearic acid |
| FDA Mainterm (IAUFC) | 106-14-9 ; 12-HYDROXYSTEARIC ACID |
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 82.00 °C. @ 760.00 mm Hg (est) |
| Boiling Point | 436.28 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure | 1.940000 mmHg @ 25.00 °C. (est) |
| Flash Point | 449.00 °F. TCC ( 231.80 °C. ) (est) |
| logP (o/w) | 5.767 (est) |
| Soluble in | water, 0.3315 mg/L @ 25 °C (est) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | cleansing agents |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | cosmetic agents |
| Recommendation for 12-hydroxystearic acid usage levels up to | not for fragrance use. |
| Recommendation for 12-hydroxystearic acid flavor usage levels up to | not for flavor use. |
BOC Sciences
Best of Chemicals Supplier
Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...
Penta International Corporation
Chemistry innovation
At Penta, our products and services help businesses do business better.
Potential Uses
Natural Occurrence
Synonyms
harwax A
hydrofol acid 200
12-
hydroxy stearic acid
DL-12-
hydroxy stearic acid
12-
hydroxy-octadecanoic acid
12-
hydroxyoctadecanoic acid
hydroxystearic acid
DL-12-
hydroxystearic acid
loxiol G 21
octadecanoic acid, 12-hydroxy-
stearic acid, 12-hydroxy-
PubMed:
Allergic contact dermatitis from 12-hydroxystearic Acid and hydrogenated castor oil.
PubMed:
Synthesis of new sugar-based surfactants and evaluation of their hemolytic activities.
PubMed:
Long chain oxoaldehydes and oxoalcohols from esters as major constituents of the surface lipids of Manduca sexta pupae in diapause.
PubMed:
Occurrence of fatty acid chlorohydrins in jellyfish lipids.
PubMed:
Aqueous dispersions of organogel nanoparticles - potential systems for cosmetic and dermo-cosmetic applications.
PubMed:
Yielding and flow of solutions of thermoresponsive surfactant tubes: tuning macroscopic rheology by supramolecular assemblies.
PubMed:
Interaction between surfactants and colloidal latexes in nonpolar solvents studied using contrast-variation small-angle neutron scattering.
PubMed:
Poly(dimethylsiloxane)-stabilized polymer particles from radical dispersion polymerization in nonpolar solvent:influence of stabilizer properties and monomer type [corrected].
PubMed:
Increased production of γ-lactones from hydroxy fatty acids by whole Waltomyces lipofer cells induced with oleic acid.
PubMed:
Cooling rate effects on the microstructure, solid content, and rheological properties of organogels of amides derived from stearic and (R)-12-hydroxystearic acid in vegetable oil.
PubMed:
Gelled oil particles: a new approach to encapsulate a hydrophobic metallophthalocyanine.
PubMed:
Phase-selective sorbent xerogels as reclamation agents for oil spills.
PubMed:
Lipid-based microtubes for topical delivery of amphotericin B.
PubMed:
Thermoreversible luminescent organogels doped with Eu(TTA)3phen complex.
PubMed:
Nanoincorporation of layered double hydroxides into a miscible blend system of cellulose acetate with poly(acryloyl morpholine).
PubMed:
Solvation effects with a photoresponsive two-component 12-hydroxystearic acid-azobenzene additive organogel.
PubMed:
CriticalSorb: a novel efficient nasal delivery system for human growth hormone based on Solutol HS15.
PubMed:
A structural study of an organogel investigated by small-angle neutron scattering and synchrotron small-angle X-ray scattering.
PubMed:
Allergic contact dermatitis caused by bis-diglycerylpolyacyladipate-2 (Softisan® 649) owing to its 12-hydroxystearic acid content.
PubMed:
Multiscale structural characterizations of fatty acid multilayered tubes with a temperature-tunable diameter.
PubMed:
Revisiting the synthesis of a well-known comb-graft copolymer stabilizer and its application to the dispersion polymerization of poly(methyl methacrylate) in organic media.
PubMed:
Pair interaction potentials of colloids by extrapolation of confocal microscopy measurements of collective suspension structure.
PubMed:
Structural relationships in 2,3-bis-n-decyloxyanthracene and 12-hydroxystearic acid molecular gels and aerogels processed in supercritical CO(2).
PubMed:
Preparation and evaluation of microporous organogel scaffolds for cell viability and proliferation.
PubMed:
Characterization of organogel as a novel oral controlled release formulation for lipophilic compounds.
PubMed:
Allergic contact dermatitis from 12-hydroxystearic Acid and hydrogenated castor oil.
PubMed:
12-Hydroxystearic acid lipid tubes under various experimental conditions.
PubMed:
Rheological characterization of a new type of colloidal dispersion based on nanoparticles of gelled oil.
PubMed:
Solvent-modulated nucleation and crystallization kinetics of 12-hydroxystearic acid: a nonisothermal approach.
PubMed:
Nanoengineering of a biocompatible organogel by thermal processing.
PubMed:
Robust organogels from nitrogen-containing derivatives of (R)-12-hydroxystearic acid as gelators: comparisons with gels from stearic acid derivatives.
PubMed:
Low molecular mass organogelator based gel electrolyte with effective charge transport property for long-term stable quasi-solid-state dye-sensitized solar cells.
PubMed:
Detailed structural elucidation of polyesters and acrylates using Fourier transform mass spectrometry.
PubMed:
Electrostatic charging of nonpolar colloids by reverse micelles.
PubMed:
Synthesis of new sugar-based surfactants and evaluation of their hemolytic activities.
PubMed:
Preparation of monodisperse, fluorescent PMMA-latex colloids by dispersion polymerization.
PubMed:
Production of gamma-lactones by the brown-rot basidiomycete Piptoporus soloniensis.
PubMed:
Effect of fatty acids on the membrane potential of an alkaliphilic bacillus.
PubMed:
How hard is a colloidal "hard-sphere" interaction?
PubMed:
Ricinoleic acid-based biopolymers.
PubMed:
The phosphatidyl-myo-inositol anchor of the lipoarabinomannans from Mycobacterium bovis bacillus Calmette Guérin. Heterogeneity, structure, and role in the regulation of cytokine secretion.
PubMed:
Selective inhibition of cyclic AMP-dependent protein kinase by amphiphilic triterpenoids and related compounds.
PubMed:
Solutol HS 15, nontoxic polyoxyethylene esters of 12-hydroxystearic acid, reverses multidrug resistance.
PubMed:
Isolation of mast cells from rabbit lung and liver: comparison of histamine release induced by the hypnotics Althesin and propanidid.
PubMed:
Comparison of the histamine-releasing activity of cremophor E1 and some of its derivatives in two experimental models: the in vivo anaesthetized dog and in vitro rat peritoneal mast cells.
PubMed:
Long chain oxoaldehydes and oxoalcohols from esters as major constituents of the surface lipids of Manduca sexta pupae in diapause.
PubMed:
The active part of the [6]-gingerol molecule in mutagenesis.
PubMed:
Histamine release and hypotensive reactions in dogs by solubilizing agents and fatty acids: analysis of various components in cremophor El and development of a compound with reduced toxicity.
PubMed:
Occurrence of fatty acid chlorohydrins in jellyfish lipids.