2,5-dihydroxyacetophenone

2-acetylhydroquinone

CAS: 490-78-8 C8 H8 O3 MW: 152.14936000

Identification

Name2,5-dihydroxyacetophenone
IUPAC1-(2,5-dihydroxyphenyl)ethanone
CAS Number490-78-8
EINECS207-716-4
FDA UNIIK1H7QH11ZH
Molecular FormulaC8 H8 O3
Molecular Weight152.14936000
MDL NumberMFCD00002343
Nikkaji NumberJ6.045C
Beilstein0637903
XlogP31.70 (est)

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 329.20 °C. @ 760.00 mm Hg (est)
Flash Point 333.00 °F. TCC ( 167.10 °C. ) (est)
logP (o/w) 1.274 (est)
Soluble in water, 1.507e+004 mg/L @ 25 °C (est)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesantioxidants

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityintraperitoneal-mouse LDLo 500 mg/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorycosmetic agents
Recommendation for 2,5-dihydroxyacetophenone usage levels up tonot for fragrance use.
Recommendation for 2,5-dihydroxyacetophenone flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

acetophenone, 2',5'-dihydroxy- 2- acetyl-1,4-dihydroxybenzene 1- acetyl-2,5-dihydroxybenzene 2- acetylhydroquinone 2',5'- dihydroxy acetophenone 1-(2,5- dihydroxy-phenyl)-ethanone 2`,5`- dihydroxyacetophenone 2',5'- dihydroxyacetophenone 2,5- dihydroxyphenyl methyl ketone 1-(2,5- dihydroxyphenyl)ethan-1-one 1-(2,5- dihydroxyphenyl)ethanone ethanone, 1-(2,5-dihydroxyphenyl)- quinacetophenone PubMed: Tissue protein imaging at 1 μm laser spot diameter for high spatial resolution and high imaging speed using transmission geometry MALDI TOF MS. PubMed: Pulse-heating ionization for protein on-chip mass spectrometry. PubMed: A new matrix assisted ionization method for the analysis of volatile and nonvolatile compounds by atmospheric probe mass spectrometry. PubMed: Aqueous ionic liquid based ultrasonic assisted extraction of four acetophenones from the Chinese medicinal plant Cynanchum bungei Decne. PubMed: 2,5-dihydroxyacetophenone isolated from Rehmanniae Radix Preparata inhibits inflammatory responses in lipopolysaccharide-stimulated RAW264.7 macrophages. PubMed: Chemical constituents of Cynanchum wilfordii and the chemotaxonomy of two species of the family Asclepiadacease, C. wilfordii and C. auriculatum. PubMed: Murine tyrosinase inhibitors from Cynanchum bungei and evaluation of in vitro and in vivo depigmenting activity. PubMed: Laserspray ionization, a new method for protein analysis directly from tissue at atmospheric pressure with ultrahigh mass resolution and electron transfer dissociation. PubMed: Laserspray ionization-ion mobility spectrometry-mass spectrometry: baseline separation of isomeric amyloids without the use of solvents desorbed and Ionized directly from a surface. PubMed: 355 nm multiphoton dissociation and ionization of 2, 5-dihydroxyacetophenone. PubMed: Optimal preparation methods for automated matrix-assisted laser desorption/ionization time-of-flight mass spectrometry profiling of low molecular weight proteins and peptides. PubMed: [Determination of four acetophenones in Radix Cynanchi bungei by high performance liquid chromatography-photodiode array detection]. PubMed: Studies on quinones. Part 45: novel 7-aminoisoquinoline-5,8-quinone derivatives with antitumor properties on cancer cell lines. PubMed: Photodissociation dynamics of 2,5-dihydroxyacetophenone. PubMed: 2,5-Dihydroxyacetophenone: a matrix for highly sensitive matrix-assisted laser desorption/ionization time-of-flight mass spectrometric analysis of proteins using manual and automated preparation techniques. PubMed: Aldose reductase inhibitors from the fruiting bodies of Ganoderma applanatum. PubMed: Practical enantioselective synthesis of endothelin antagonist S-1255 by dynamic resolution of 4-methoxychromene-3-carboxylic acid intermediate. PubMed: Effects of 4,4-dimethyl-5,8-dihydroxynaphtalene-1-one and 4,4-dimethyl-5,8-dihydroxytetralone derivatives on tumor cell respiration. PubMed: Stereochemistry and biological activities of constituents from Cynanchum taiwanianum. PubMed: Synthesis of 4'- and 5'-hydroxyoxprenolol:pharmacologically active ring-hydroxylated metabolites of oxprenolol.