2,5-dihydroxyacetophenone
2-acetylhydroquinone
Identification
| Name | 2,5-dihydroxyacetophenone |
| IUPAC | 1-(2,5-dihydroxyphenyl)ethanone |
| CAS Number | 490-78-8 |
| EINECS | 207-716-4 |
| FDA UNII | K1H7QH11ZH |
| Molecular Formula | C8 H8 O3 |
| Molecular Weight | 152.14936000 |
| MDL Number | MFCD00002343 |
| Nikkaji Number | J6.045C |
| Beilstein | 0637903 |
| XlogP3 | 1.70 (est) |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 329.20 °C. @ 760.00 mm Hg (est) |
| Flash Point | 333.00 °F. TCC ( 167.10 °C. ) (est) |
| logP (o/w) | 1.274 (est) |
| Soluble in | water, 1.507e+004 mg/L @ 25 °C (est) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | antioxidants |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | intraperitoneal-mouse LDLo 500 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | cosmetic agents |
| Recommendation for 2,5-dihydroxyacetophenone usage levels up to | not for fragrance use. |
| Recommendation for 2,5-dihydroxyacetophenone flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
acetophenone, 2',5'-dihydroxy-
2-
acetyl-1,4-dihydroxybenzene
1-
acetyl-2,5-dihydroxybenzene
2-
acetylhydroquinone
2',5'-
dihydroxy acetophenone
1-(2,5-
dihydroxy-phenyl)-ethanone
2`,5`-
dihydroxyacetophenone
2',5'-
dihydroxyacetophenone
2,5-
dihydroxyphenyl methyl ketone
1-(2,5-
dihydroxyphenyl)ethan-1-one
1-(2,5-
dihydroxyphenyl)ethanone
ethanone, 1-(2,5-dihydroxyphenyl)-
quinacetophenone
PubMed:
Tissue protein imaging at 1 μm laser spot diameter for high spatial resolution and high imaging speed using transmission geometry MALDI TOF MS.
PubMed:
Pulse-heating ionization for protein on-chip mass spectrometry.
PubMed:
A new matrix assisted ionization method for the analysis of volatile and nonvolatile compounds by atmospheric probe mass spectrometry.
PubMed:
Aqueous ionic liquid based ultrasonic assisted extraction of four acetophenones from the Chinese medicinal plant Cynanchum bungei Decne.
PubMed:
2,5-dihydroxyacetophenone isolated from Rehmanniae Radix Preparata inhibits inflammatory responses in lipopolysaccharide-stimulated RAW264.7 macrophages.
PubMed:
Chemical constituents of Cynanchum wilfordii and the chemotaxonomy of two species of the family Asclepiadacease, C. wilfordii and C. auriculatum.
PubMed:
Murine tyrosinase inhibitors from Cynanchum bungei and evaluation of in vitro and in vivo depigmenting activity.
PubMed:
Laserspray ionization, a new method for protein analysis directly from tissue at atmospheric pressure with ultrahigh mass resolution and electron transfer dissociation.
PubMed:
Laserspray ionization-ion mobility spectrometry-mass spectrometry: baseline separation of isomeric amyloids without the use of solvents desorbed and Ionized directly from a surface.
PubMed:
355 nm multiphoton dissociation and ionization of 2, 5-dihydroxyacetophenone.
PubMed:
Optimal preparation methods for automated matrix-assisted laser desorption/ionization time-of-flight mass spectrometry profiling of low molecular weight proteins and peptides.
PubMed:
[Determination of four acetophenones in Radix Cynanchi bungei by high performance liquid chromatography-photodiode array detection].
PubMed:
Studies on quinones. Part 45: novel 7-aminoisoquinoline-5,8-quinone derivatives with antitumor properties on cancer cell lines.
PubMed:
Photodissociation dynamics of 2,5-dihydroxyacetophenone.
PubMed:
2,5-Dihydroxyacetophenone: a matrix for highly sensitive matrix-assisted laser desorption/ionization time-of-flight mass spectrometric analysis of proteins using manual and automated preparation techniques.
PubMed:
Aldose reductase inhibitors from the fruiting bodies of Ganoderma applanatum.
PubMed:
Practical enantioselective synthesis of endothelin antagonist S-1255 by dynamic resolution of 4-methoxychromene-3-carboxylic acid intermediate.
PubMed:
Effects of 4,4-dimethyl-5,8-dihydroxynaphtalene-1-one and 4,4-dimethyl-5,8-dihydroxytetralone derivatives on tumor cell respiration.
PubMed:
Stereochemistry and biological activities of constituents from Cynanchum taiwanianum.
PubMed:
Synthesis of 4'- and 5'-hydroxyoxprenolol:pharmacologically active ring-hydroxylated metabolites of oxprenolol.