2,4-xylidine

benzenamine, 2,4-dimethyl-

CAS: 95-68-1 C8 H11 N MW: 121.18267000

Identification

Name2,4-xylidine
CAS Number95-68-1
EINECS202-440-0
FDA UNII367R1L22C9
Molecular FormulaC8 H11 N
Molecular Weight121.18267000
MDL NumberMFCD00007738
Nikkaji NumberJ358A
Beilstein0636243
XlogP31.70 (est)

Regulatory

Physical Properties

Appearance dark brown liquid (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 0.98000 @ 25.00 °C.
Melting Point -14.30 °C. @ 760.00 mm Hg (est)
Boiling Point 214.00 °C. @ 760.00 mm Hg
Vapor Pressure 0.154000 mmHg @ 25.00 °C. (est)
Flash Point 195.00 °F. TCC ( 90.56 °C. )
logP (o/w) 1.680
Soluble in water, 3652 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityoral-mouse LD50 250 mg/kg
Dermal ToxicityNot determined
Inhalation Toxicityinhalation-mouse LC50 149 ppm/7H

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorypharmaceuticals / chemical synthisis
Recommendation for 2,4-xylidine usage levels up tonot for fragrance use.
Recommendation for 2,4-xylidine flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

4- amino-1,3-dimethylbenzene 4- amino-1,3-xylene 1- amino-2,4-dimethylbenzene aniline, 2,4-dimethyl- benzenamine, 2,4-dimethyl- 2,4- dimethyl aniline 2,4- dimethyl-benzenamine 2,4- dimethyl-phenylamine 2,4- dimethylanilin 2,4- dimethylaniline 2,4- dimethylbenzenamine 2,4- dimethylbenzene-1-amine 2,4- dimethylbenzeneamine 2,4- dimethylphenylamine 2- methyl-p-toluidine 2- methyl-para-toluidine m- xylidine 2,4- xylylamine PubMed: Determination method for xylidines in workplace air. PubMed: Simultaneous determination of amitraz and its metabolite residue in food animal tissues by gas chromatography-electron capture detector and gas chromatography-mass spectrometry with accelerated solvent extraction. PubMed: Determination of amitraz and 2,4-dimethylaniline residues in honey by using LC with UV detection and MS/MS. PubMed: Separation and analysis of dimethylaniline isomers by supercritical fluid chromatography--electrospray ionization tandem mass spectrometry. PubMed: Determination of amitraz and its transformation products in pears by ethyl acetate extraction and liquid chromatography-tandem mass spectrometry. PubMed: Directed evolution of aniline dioxygenase for enhanced bioremediation of aromatic amines. PubMed: Anaerobic metabolism of 1-amino-2-naphthol-based azo dyes (Sudan dyes) by human intestinal microflora. PubMed: Probing the molecular determinants of aniline dioxygenase substrate specificity by saturation mutagenesis. PubMed: Identification of pesticide transformation products in food by liquid chromatography/time-of-flight mass spectrometry via "fragmentation-degradation" relationships. PubMed: Electrochemical monitoring of the biodegradation of 2,4-dimethylaniline. PubMed: Electrochemical investigation of the effect of pH and solvent on amitraz stability. PubMed: [Cosmetic colorants. Toxicology and regulation]. PubMed: Oxidative degradation of 2,4-xylidine by photosensitization with 2,4,6-triphenylpyrylium: homogeneous and heterogeneous catalysis. PubMed: Liquid phase overtone spectral investigations of 2,6-dimethylaniline and 2,4-dimethylaniline-evidence for steric nature of the ortho effect and the consequent base weakening. PubMed: New insights into the mechanisms of the thermal Fenton reactions occurring using different iron(II)-complexes. PubMed: Ruthenium(II)-tris-bipyridine/titanium dioxide codoped zeolite Y photocatalysts: II. Photocatalyzed degradation of the model pollutant 2,4-xylidine, evidence for percolation behavior. PubMed: [FeII(bpy)3]2+/TiO2-codoped zeolites: synthesis, characterization, and first application in photocatalysis. PubMed: Teratogenic effects of amitraz, 2,4-dimethylaniline, and paraquat on developing frog (Xenopus) embryos. PubMed: An N,N'-dialkyl-4,4'-bipyridinium-modified titanium-dioxide photocatalyst for water remediation--observation and application of supramolecular effects in photocatalytic degradation of pi-donor organic compounds. PubMed: Optimal experimental design and artificial neural networks applied to the photochemically enhanced Fenton reaction. PubMed: Assessment of aniline derivatives-induced DNA damage in the liver cells of B6C3F1 mice using the alkaline single cell gel electrophoresis ('comet') assay. PubMed: Assessment of aniline derivatives-induced DNA damage in the liver cells of B6C3F1 mice using the alkaline single cell gel electrophoresis ("comet") assay. PubMed: An evaluation of the DNA damaging effect of selected aniline derivatives using the alkaline single cell gel electrophoresis ("comet") assay. PubMed: The genotoxicity of a variety of aniline derivatives in a DNA repair test with primary cultured rat hepatocytes. PubMed: [Various characteristics of the combined effects of chemical substances on the body after their inhalation and skin absorption]. PubMed: Metabolic activation of 2,4-xylidine and its mutagenic metabolite. PubMed: Serum bile acid concentration in some experimental liver lesions of rat. PubMed: Testing of twenty-one environmental aromatic amines or derivatives for long-term toxicity or carcinogenicity. PubMed: 2,4-xylidine (hydrochloride). PubMed: Personal air sampling for vapors of aniline compounds. PubMed: Proceedings: Early biochemical and morphological changes in the liver of mice after a single oral administration of 2,4-xylidine.