(Z)-3-hexen-1-yl salicylate

cis-3-hexenyl salicylate

CAS: 65405-77-8 C13 H16 O3 MW: 220.26812000 floral green

Identification

Name(Z)-3-hexen-1-yl salicylate
IUPAC[(Z)-hex-3-enyl] 2-hydroxybenzoate
CAS Number65405-77-8
EINECS265-745-8
FDA UNIIC78Y9OR6YH
Molecular FormulaC13 H16 O3
Molecular Weight220.26812000
MDL NumberMFCD00036486
Nikkaji NumberJ76.332B
CoE Number10685
XlogP34.40 (est)

Regulatory

DG SANTE Food Flavourings09.570 (Z)-hex-3-enyl salicylate
FEMA Number4750
FDANo longer provide for the use of these seven synthetic flavoring substances

Physical Properties

Appearance colorless clear oily liquid (est)
Assay 98.00 to 100.00 sum of isomers
Food Chemicals Codex Listed No
Specific Gravity 1.05700 to 1.06500 @ 25.00 °C., 1.05700 to 1.06500 @ 20.00 °C.
Pounds per Gallon - (est). 8.795 to 8.862
Pounds per Gallon - est. 8.806 to 8.872
Refractive Index 1.51800 to 1.52200 @ 20.00 °C.
Melting Point 139.00 °C. @ 760.00 mm Hg
Boiling Point 145.00 °C. @ 5.00 mm Hg, 394.00 °C. @ 760.00 mm Hg
Vapor Pressure 0.000246 mmHg @ 25.00 °C. (est)
Vapor Density >1 ( Air = 1 )
Flash Point 230.00 °F. TCC ( 110.00 °C. )
logP (o/w) 4.630
Shelf Life 24.00 month(s) or longer if stored properly.
Storage store in cool, dry place in tightly sealed containers, protected from heat and light.
Soluble in alcohol
Insoluble in water
Stability acid cleaner
Similar Items note

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesperfuming agents

Organoleptic Properties

Odor Strength medium
Substantivity 216 hour(s) at 100.00 %
Odor Description
at 100.00 %.
A floral (lily of the valley) green note
Apparently mild odored in the herbaceous/green family, but an excellent blending agent. Floral, sea
herbaceous, curative, woody, skin
green aromatic floral phenolic-medicinal leathery-mossy
Fresh, sweet-floral, green-balsamic, salicylate
Fresh, floral fragrance with green herbaceous and balsamic shades
Green, salicylate, floral, sweet
Odor sample from Bedoukian Research, Inc.
Taste Description
green melon fruity floral metallic herbal cilantro soapy vegetable
fruity
floreal, medicinal, ethereal
sweet, green, floral, woody and balsamic
sweet, green, floral, woody and balsamic

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Oral/Parenteral Toxicityoral-rat LD50 5000 mg/kg
Dermal Toxicityskin-rabbit LD50 > 5000 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavor and fragrance agents
RIFM Fragrance Material Safety AssessmentSearch
maximum skin levels for fine fragrances2.0200 % and are based on the assumption that the fragrance mixture is used at 20% in a consumer product (IFRA Use Level Survey). (IFRA, 2002)
Recommendation for (Z)-3-hexen-1-yl salicylate usage levels up to5.0000 % in the fragrance concentrate.
use level in formulae for use in cosmetics3.9611 %
Dermal Systemic Exposure in Cosmetic Products0.1009 mg/kg/day (IFRA, 2002)
Maximised Survey-derived Daily Intakes (MSDI-EU)0.13 (μg/capita/day)
Modified Theoretical Added Maximum Daily Intake (mTAMDI)3900 (μg/person/day)
Threshold of Concern1800 (μg/person/day)
Structure ClassI
baked goods0.30000
beverages(nonalcoholic)0.15000
beverages(alcoholic)0.15000
breakfast cereal0.30000
cheese-
chewing gum0.50000
condiments / relishes-
confectionery froastings0.50000
egg products-
fats / oils-
fish products-
frozen dairy0.50000
fruit ices0.50000
gelatins / puddings0.50000
granulated sugar-
gravies-
hard candy0.50000
imitation dairy0.50000
instant coffee / tea-
jams / jellies0.50000
meat products-
milk products0.50000
nut products0.50000
other grains0.50000
poultry-
processed fruits0.50000
processed vegetables-
reconstituted vegetables-
seasonings / flavors0.50000
snack foods0.50000
soft candy0.50000
soups-
sugar substitutes-
sweet sauces0.50000
Dairy products, excluding products of category 02.0 (01.0)7.00000
Fats and oils, and fat emulsions (type water-in-oil) (02.0)5.00000
Edible ices, including sherbet and sorbet (03.0)10.00000
Processed fruit (04.1)7.00000
Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2)-
Confectionery (05.0)10.00000
Chewing gum (05.3)-
Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0)5.00000
Bakery wares (07.0)10.00000
Meat and meat products, including poultry and game (08.0)2.00000
Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0)2.00000
Eggs and egg products (10.0)-
Sweeteners, including honey (11.0)-
Salts, spices, soups, sauces, salads, protein products, etc. (12.0)5.00000
Foodstuffs intended for particular nutritional uses (13.0)10.00000
Non-alcoholic ("soft") beverages, excl. dairy products (14.1)5.00000
Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2)10.00000
Ready-to-eat savouries (15.0)20.00000
Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0)5.00000

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Azelis UK Ltd.

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Bedoukian Research, Inc.

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Berje Inc.

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Indukern, S.A. F&F Ingredients Division

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Jiangyin Healthway International Trade Co., Ltd

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Pell Wall Perfumes

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The Lermond Company

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Potential Uses

FR agrumen aldehyde FR algae FR animal FR crabapple FL artichoke FR ash mountain ash FR ash mountain ash blossom FL asparagus FR avocado FR balsam FR bark FR bayberry FR botanical FR boxwood FR boxwood blossom FR boxwood berry FR carnation FL/FR carrot seed FR cedar forest FR celery charlie FR cherry black cherry FR christmas FR chrysanthemum FR chypre clean FR clover FR colonia FR coronilla FR country meadow FR crabapple blossom FR cucumber FR cyclamen FR daffodil FR dillenia FR earth FR elder berry FR elder flower fantasy blends FR fern FR fig FR fir balsam fixer FR floral FR flouve FR foliage FR forest FR freesia FR fresh and clean FR fungus FL/FR galangal root FR ginger white ginger FR gooseberry FR green FR green leaf FR hay new mown hay FR heather FR herbal FR hollyberry FR hyacinth FR hydrangea FR iris blossom FR kewda FR kiwi FR kiwi blossom FR leather FR lily FR lily of the valley FR lotus FR lychee FR magnolia FR mango flower FR melon FR moss FR musk FR narcissus FR new car FL nut FR ocean sea FR orchid FR pansy FR peach blossom FL pear prickly pear FR peony FR phlox FR pine FR pomegranate FR poppy FR privet FR privet blossom FR rain FR redwood FR reseda FR rhubarb FR rose tea rose FR rose white rose rose wild rose FR scented stock FR stephanotis FR stephanotis FR sweet grass FR sweet pea FL tea FR tobacco FR tuberose FR tulip FR verbena FR violet FR woody FL/FR yerba mate FR yew

Natural Occurrence

witch hazel leaf oil @ 0.01% Data

Synonyms

benzoic acid, 2-hydroxy-, (3Z)-3-hexen-1-yl ester benzoic acid, 2-hydroxy-, (3Z)-3-hexenyl ester benzoic acid, 2-hydroxy-, 3-hexenyl ester, (Z)- (3Z)- hex-3-en-1-yl 2-hydroxybenzoate (3Z)- hex-3-en-1-yl salicylate (Z)- hex-3-enyl 2-hydroxybenzoate (Z)- hex-3-enyl salicylate [(Z)- hex-3-enyl] 2-hydroxybenzoate (Z)-3- hexen-1-yl 2-hydroxybenzoate (3Z)-3- hexen-1-yl salicylate (Z)-3- hexen-1-yl salicylate cis-3- hexen-1-yl salicylate hexenyl cis-3 salicylate (Z)-3- hexenyl salicylate C3 hexenyl salicylate cis 3- hexenyl salicylate cis-3- hexenyl salicylate hexenyl salicylate cis-3 cis-3- hexenyl salicylate extra cis-3- hexenyl salicylate natural hexenyl-3-cis salicylate cis-3- hexenyle salicylate leaf salicylate salicylic acid cis-3-hexen-1-yl ester PubMed: Allergic contact dermatitis from octisalate and cis-3-hexenyl salicylate. PubMed: Sensitization to cis-3-hexenyl salicylate.