2-benzyl pyridine
pyridine, 2-(phenylmethyl)-
Identification
| Name | 2-benzyl pyridine |
| IUPAC | 2-benzylpyridine |
| CAS Number | 101-82-6 |
| EINECS | 202-979-1 |
| FDA UNII | EW2N4V60MQ |
| Molecular Formula | C12 H11 N |
| Molecular Weight | 169.22667000 |
| MDL Number | MFCD00006352 |
| Nikkaji Number | J36.122D |
| Beilstein | 0115875 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Specific Gravity | 1.05400 to 1.05900 @ 20.00 °C. |
| Pounds per Gallon - (est). | 8.781 to 8.822 |
| Refractive Index | 1.57600 to 1.58200 @ 20.00 °C. |
| Melting Point | 12.50 °C. @ 760.00 mm Hg |
| Boiling Point | 277.00 °C. @ 760.00 mm Hg, 266.00 to 267.00 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure | 0.008000 mmHg @ 25.00 °C. (est) |
| Flash Point | 257.00 °F. TCC ( 125.00 °C. ) |
| logP (o/w) | 2.570 (est) |
| Soluble in | alcohol |
| Insoluble in | water |
Organoleptic Properties
| Taste Description | green astringent |
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | subcutaneous-mouse LD50 1500 mg/kg |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for 2-benzyl pyridine usage levels up to | not for fragrance use. |
| Recommendation for 2-benzyl pyridine flavor usage levels up to | not for flavor use. |
Penta International Corporation
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Potential Uses
Natural Occurrence
Synonyms
2-
benzylpyridine
2-(
phenylmethyl)pyridine
pyridine, 2-(phenylmethyl)-
pyridine, 2-benzyl-
US Patents:
3,931,166 - Certain 2,5-dimethyl-3-thiopyrazines
PubMed:
Spectroscopic (FTIR, FT-Raman, UV and NMR) investigation and NLO, HOMO-LUMO, NBO analysis of 2-Benzylpyridine based on quantum chemical calculations.
US Patents:
Flavoring agent
PubMed:
Copper-catalyzed α-methylenation of benzylpyridines using dimethylacetamide as one-carbon source.
PubMed:
Ruthenium(II) complexes of 2-benzoylpyridine-derived thiosemicarbazones with cytotoxic activity against human tumor cell lines.
PubMed:
Interaction between tetramethylcucurbit[6]uril and some pyridine derivates.
PubMed:
Synthesis, characterization, and preliminary oxygenation studies of benzyl- and ethyl-substituted pyridine ligands of carboxylate-rich diiron(II) complexes.
PubMed:
Oxidation of sulfide, phosphine, and benzyl substrates tethered to N-donor pyridine ligands in carboxylate-bridged diiron(II) complexes.
PubMed:
Reactions of an amphoteric terminal tungsten methylidyne complex.
PubMed:
Induction of hepatic microsomal cytochrome P450 and drug-metabolizing enzymes by 4-benzylpyridine and its structurally related compounds in rats. Dose- and sex-related differential induction of cytochrome P450 species.
PubMed:
Drug metabolizing enzyme induction by simple diaryl pyridines; 2-substituted isomers selectively increase only conjugation enzyme activities, 4-substituted isomers also induce cytochrome P450.
PubMed:
alpha-(2-Pyridine)benzyl aryl ketones as potential hypocholesteremic agents.