glycol salicylate

2-hydroxybenzoic acid, 2-hydroxyethyl ester

CAS: 87-28-5 C9 H10 O4 MW: 182.17550000

Identification

Nameglycol salicylate
IUPAC2-hydroxyethyl 2-hydroxybenzoate
CAS Number87-28-5
EINECS201-737-2
FDA UNII3I1VBB7AXH
Molecular FormulaC9 H10 O4
Molecular Weight182.17550000
MDL NumberMFCD00002862
Nikkaji NumberJ55.649A
Beilstein2255685
XlogP31.90 (est)

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 1.24400 @ 25.00 °C.
Melting Point 37.00 °C. @ 760.00 mm Hg
Boiling Point 294.00 to 295.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure 0.001000 mmHg @ 25.00 °C. (est)
Flash Point 263.00 °F. TCC ( 128.30 °C. ) (est)
logP (o/w) 1.519 (est)
Soluble in alcohol

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesuv absorbers

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorycosmetic UV absorber
Recommendation for glycol salicylate usage levels up tonot for fragrance use.
Recommendation for glycol salicylate flavor usage levels up tonot for flavor use.

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Potential Uses

u.v. absorbers

Natural Occurrence

not found in nature

Synonyms

benzoic acid, 2-hydroxy-, 2-hydroxyethyl ester ethylene glycol monosalicylate 1,2- ethylene glycol monosalicylate ethylene glycol salicylate glycol monosalicylate mono glycol salicylate 2- hydroxybenzoic acid 2-hydroxyethyl ester 2- hydroxybenzoic acid, 2-hydroxyethyl ester 2- hydroxyethyl 2-hydroxybenzoate 2- hydroxyethyl salicylate rheumacyl salicylic acid 2-hydroxyethyl ester salicylic acid ethylene glycol ester salicylic acid, 2-hydroxyethyl ester sarocol spirosal traumasenex PubMed: Optimization and validation of liquid chromatography and headspace-gas chromatography based methods for the quantitative determination of capsaicinoids, salicylic acid, glycol monosalicylate, methyl salicylate, ethyl salicylate, camphor and l-menthol in a topical formulation. PubMed: Allergic contact dermatitis from a veterinary antiinflammatory gel containing 2-hydroxyethyl salicylate. PubMed: Contact dermatitis due to topical drugs. PubMed: Synergetic analgesic effect of the combination of arnica and hydroxyethyl salicylate in ethanolic solution following cutaneous application by transcutaneous electrostimulation. PubMed: Contact dermatitis from anti-inflammatory gel containing hydroxyethyl salicylate. PubMed: Topical penetration of commercial salicylate esters and salts using human isolated skin and clinical microdialysis studies. PubMed: Contact dermatitis from hydroxyethyl salicylate. PubMed: [Therapy of rheumatic disease with a hydroxyethylsalicylate gel. Results of 2 clinical studies of effectiveness and bioavailability]. PubMed: Reduced vasoactive responses in port wine stains. PubMed: Thermodynamics of distribution of salicylates in semi-solid ointment bases. PubMed: [On interactions of drugs on and in the skin/comparative studies on the mutual influences of ethyleneglycol-monosalicylate and benzylnicotinate (author's transl)]. PubMed: [Influence of the excipient on the absorption of glycol salicylate administered in ointments by cutaneous and rectal routes].