2-methoxyethanol

ethanol, 2-methoxy-

CAS: 109-86-4 C3 H8 O2 MW: 76.09516000

Identification

Name	2-methoxyethanol
IUPAC	2-methoxyethanol
CAS Number	109-86-4
EINECS	203-713-7
FDA UNII	EK1L6XWI56
Molecular Formula	C3 H8 O2
Molecular Weight	76.09516000
MDL Number	MFCD00002867
Nikkaji Number	J2.442B
Beilstein	1731074
XlogP3	-0.80 (est)

Regulatory

FDA Mainterm (IAUFC)

109-86-4 ; ETHYLENE GLYCOL MONOMETHYL ETHER

Physical Properties

Appearance	colorless clear liquid (est)
Assay	95.00 to 100.00
Food Chemicals Codex Listed	No
Specific Gravity	0.96500 @ 25.00 °C.
Melting Point	-85.10 °C. @ 760.00 mm Hg (est)
Boiling Point	124.10 °C. @ 760.00 mm Hg
Vapor Pressure	5.975000 mmHg @ 25.00 °C. (est)
Vapor Density	2.62 ( Air = 1 )
Flash Point	115.00 °F. TCC ( 46.11 °C. )
logP (o/w)	-0.770
Soluble in	water, 1.00E+06 mg/L @ 25 °C (exp)

No sensory data available

Safety Information

Oral/Parenteral Toxicity	oral-guinea pig LD50 950 mg/kg
Dermal Toxicity	skin-rabbit LD50 1280 mg/kg
Inhalation Toxicity	inhalation-human TCLo 25 ppm

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements', 'BLOOD: CHANGES IN SPLEEN\nBLOOD: OTHER CHANGES\nKIDNEY, URETER, AND BLADDER: CHANGES IN BOTH TUBULES AND GLOMERULI', 'BEHAVIORAL: GENERAL ANESTHETIC\nBLOOD: OTHER HEMOLYSIS WITH OR WITHOUT ANEMIA', 'BLOOD: OTHER HEMOLYSIS WITH OR WITHOUT ANEMIA', 'BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)\nLUNGS, THORAX, OR RESPIRATION: OTHER CHANGES']

Safety in Use

Category	pharmaceuticals / chemical synthisis
IFRA Critical Effect	Reproductive toxicity
Recommendation for 2-methoxyethanol usage levels up to	PROHIBITED: Should not be used as a fragrance ingredient.
Recommendation for 2-methoxyethanol flavor usage levels up to	not for flavor use.

Penta International Corporation

Chemistry innovation

At Penta, our products and services help businesses do business better.

13-20520 2-METHOXYETHANOL

View All Website (973) 740-2300 lisaa@pentamfg.com

Potential Uses

solvents

Natural Occurrence

not found in nature

Synonyms

amsco-solv EE anesthenyl 3-oxa-1- butanol dowanol 7 dowanol EM EGME ektasolve EM ethanol, 2-methoxy- ethylene glycol methyl ether ethylene glycol monomethyl ether glycol ether EM glycol methyl ether glycol monomethyl ether glycolmethyl ether 1- hydroxy-2-methoxyethane 2- hydroxyethyl methyl ether jeffersol EM 2- methoxy ethanol 2- methoxy-1-ethanol 2- methoxyethan-1-ol .beta.- methoxyethanol b- methoxyethanol 2- methoxyethyl alcohol methyl cellosolve mono methyl ether of ethylene glycol methyl ethoxol mono methyl ethylene glycol ether methyl glycol mono methyl glycol methyl oxitol 2- metossietanolo prist PubMed: Base-catalyzed derivatization methodology for FA analysis. application to milk fat and celery seed lipid TAG. PubMed: Toxicity review of ethylene glycol monomethyl ether and its acetate ester. PubMed: Subchronic inhalation toxicity of diglyme. PubMed: Cutaneous toxicity studies with methoxy polyethylene glycol-350 (MPEG-350) in rats and rabbits. PubMed: Mouse placenta: hemodynamics in the main maternal vessel and histopathologic changes induced by 2-methoxyethanol and 2-methoxyacetic acid following maternal dosing. PubMed: The developmental toxicity of 2-ethylhexanol applied dermally to pregnant Fischer 344 rats. PubMed: Effects of subchronic exposure of rats to 2-methoxyethanol or 2-butoxyethanol: thymic atrophy and immunotoxicity.