3,4,5-trimethoxybenzyl alcohol

benzenemethanol, 3,4,5-trimethoxy-

CAS: 3840-31-1 C10 H14 O4 MW: 198.21838000

Identification

Name3,4,5-trimethoxybenzyl alcohol
CAS Number3840-31-1
EINECS223-331-4
FDA UNIIMDV94PFP33
Molecular FormulaC10 H14 O4
Molecular Weight198.21838000
MDL NumberMFCD00004639
Nikkaji NumberJ28.532C
Beilstein2104523

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 1.19700 to 1.20100 @ 20.00 °C.
Pounds per Gallon - (est). 9.972 to 10.005
Refractive Index 1.54300 to 1.54700 @ 20.00 °C.
Flash Point > 230.00 °F. TCC ( > 110.00 °C. )
Soluble in water, 4.563e+004 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for 3,4,5-trimethoxybenzyl alcohol usage levels up tonot for fragrance use.
Recommendation for 3,4,5-trimethoxybenzyl alcohol flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

found in nature

Synonyms

benzenemethanol, 3,4,5-trimethoxy- (3,4,5- trimethoxyphenyl)methanol PubMed: New cytotoxic lignan glycosides from Phyllanthus glaucus. PubMed: Bioorganic diversity of rare Coriandrum sativum L. honey: unusual chromatographic profiles containing derivatives of linalool/oxygenated methoxybenzene. PubMed: Stability of benzylic-type isothiocyanates in hydrodistillation-mimicking conditions. PubMed: Four N(7)-alkoxybenzyl-substituted 4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridine-5-spiro-1'-cyclohexane-2',6'-diones: hydrogen-bonded supramolecular structures in zero, one, two or three dimensions. PubMed: A blocker of N- and T-type voltage-gated calcium channels attenuates ethanol-induced intoxication, place preference, self-administration, and reinstatement. PubMed: Oxidation capacity of laccases and peroxidases as reflected in experiments with methoxy-substituted benzyl alcohols. PubMed: Antimalarial agents from plants. III. Trichothecenes from Ficus fistulosa and Rhaphidophora decursiva. PubMed: Oxygen transfer reactions. 4. Reaction of high valent oxoruthenium compounds with sulfides. PubMed: Sigma receptor-mediated effects of a new antiulcer agent, KB-5492, on experimental gastric mucosal lesions and gastric alkaline secretion in rats. PubMed: Synthesis and platelet-activating factor (PAF)-antagonistic activities of trisubstituted piperazine derivatives. PubMed: Synthesis and platelet-activating factor (PAF)-antagonistic activities of 1,4-disubstituted piperazine derivatives. PubMed: Effects of KB-5492, 1-(3,4,5-trimethoxybenzyl)-4-((4-methoxyphenyl)oxycarbonylmethyl) p iperazine monofumarate monohydrate, on gastric lesions and gastric secretion in rats. PubMed: Biomimetic oxidation of nonphenolic lignin models by Mn(III): new observations on the oxidizability of guaiacyl and syringyl substructures. PubMed: Inhibition of norepinephrine transport and reserpine binding by reserpine derivatives. PubMed: The effects of colchicine analogues on the reaction of tubulin with iodo[14C]acetamide and N,N'-ethylenebis(iodoacetamide). PubMed: [Bronchodilating action of (--)-1-(3, 4, 5-trimethoxybenzyl)-7-hydroxy-1, 2, 3, 4-tetrahydroisoquinoloine HCl (l-MTI) (author's transl)]. PubMed: [Bronchodilating and cardiovascular actions of (-)-1-(3, 4, 5-trimethoxybenzyl)-5, 7-dihydroxy-1, 2, 3, 4-tetrahydroisoquinoline hydrochloride (l-DTI) in the anesthetized dog (author's transl)]. PubMed: [Vasodilating action of (+/-)-1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinoline (TMI) derivatives (author's transl)]. PubMed: [Vasodilator action of (+/-)-1-(3, 4, 5-trimethoxybenzyl)-6-hydroxy-1, 2, 3, 4-tetrahydroisoquinoline hydrochloride (CV-705) in anesthetized dogs (author's transl)]. PubMed: Bronchodilating actions of (+/-)-1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinoline (TMI) derivatives in anesthetized cats. PubMed: [Studies on tetrahydroisoquinolines. V. Actions of 1-(3, 4, 5-trimethoxybenzyl)-6, 7-dihydroxy-1, 2, 3, 4-tetrahydroisoquinoline HCL (AQ-110) on the guinea-pig papillary muscle]. PubMed: [Studies on tetrahydroisoquinoline compounds. (3). Pharmacodynamics of 1-(3,4,5-trimethoxybenzyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline HC1 (AQ-110)].