3-hydroxyanthranilic acid

3-oxyanthranilic acid

CAS: 548-93-6 C7 H7 N O3 MW: 153.13739000

Identification

Name3-hydroxyanthranilic acid
CAS Number548-93-6
EINECS208-962-5
FDA UNII1UQB1BT4OT
Molecular FormulaC7 H7 N O3
Molecular Weight153.13739000
MDL NumberMFCD00007700
Nikkaji NumberJ1.608J
Beilstein0973356
XlogP30.90 (est)

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 1.297e+004 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for 3-hydroxyanthranilic acid usage levels up tonot for fragrance use.
Recommendation for 3-hydroxyanthranilic acid flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

cauliflower

Synonyms

2- amino-3-hydroxybenzoic acid 3-oxy anthranilic acid anthranilic acid, 3-hydroxy- benzoic acid, 2-amino-3-hydroxy- PubMed: Inhibition of LPS-induced inflammatory mediators by 3-hydroxyanthranilic acid in macrophages through suppression of PI3K/NF-κB signaling pathways. PubMed: Associations between intake of fish and n-3 long-chain polyunsaturated fatty acids and plasma metabolites related to the kynurenine pathway in patients with coronary artery disease. PubMed: Pyridoxine supplementation does not alter in vivo kinetics of one-carbon metabolism but modifies patterns of one-carbon and tryptophan metabolites in vitamin B-6-insufficient oral contraceptive users. PubMed: Tryptophan catabolism and vitamin B-6 status are affected by gender and lifestyle factors in healthy young adults. PubMed: Evaluation of the bioactive properties of avenanthramide analogs produced in recombinant yeast. PubMed: Metabolite profile analysis reveals association of vitamin B-6 with metabolites related to one-carbon metabolism and tryptophan catabolism but not with biomarkers of inflammation in oral contraceptive users and reveals the effects of oral contraceptives on these processes. PubMed: The urinary ratio of 3-hydroxykynurenine/3-hydroxyanthranilic acid is an index to predicting the adverse effects of D-tryptophan in rats. PubMed: Vitamin B1 deficiency inhibits the increased conversion of tryptophan to nicotinamide in severe food-restricted rats. PubMed: Pantothenic acid deficiency may increase the urinary excretion of 2-oxo acids and nicotinamide catabolites in rats. PubMed: Metabonomic analysis of quercetin against the toxicity of chronic exposure to low-level dichlorvos in rats via ultra-performance liquid chromatography-mass spectrometry. PubMed: The niacin required for optimum growth can be synthesized from L-tryptophan in growing mice lacking tryptophan-2,3-dioxygenase. PubMed: Supplementing healthy women with up to 5.0 g/d of L-tryptophan has no adverse effects. PubMed: Increased conversion of tryptophan to nicotinamide in rats by dietary valproate. PubMed: Fate of dietary tryptophan in young Japanese women. PubMed: Urinary excretory ratio of anthranilic acid/kynurenic acid as an index of the tolerable amount of tryptophan. PubMed: Effect of nicotinamide administration on the tryptophan-nicotinamide pathway in humans. PubMed: The effects of phthalate esters on the tryptophan-niacin metabolism. PubMed: Increase in conversion of tryptophan to niacin in pregnant rats. PubMed: Influence of adenine-induced renal failure on tryptophan-niacin metabolism in rats. PubMed: Characterization of a novel manganese peroxidase-lignin peroxidase hybrid isozyme produced by Bjerkandera species strain BOS55 in the absence of manganese. PubMed: In vivo antioxidant activity of Okara Koji, a fermented okara, by Aspergillus oryzae. PubMed: Antioxidative mechanism and apoptosis induction by 3-hydroxyanthranilic acid, an antioxidant in Indonesian food Tempeh, in the human hepatoma-derived cell line, HuH-7. PubMed: Difference in Tryptophan-nicotinamide Conversion According to Dietary Nitrogen Sources; Casein, Casein Hydrolysate, and Mixtures of Amino Acids. PubMed: The effects of high dietary concentrations of sodium saccharin on in vivo metabolism of xenobiotics in rats. PubMed: Liver 3-hydroxyanthranilic acid oxygenase activity in rainbow trout (Oncorhynchus mykiss). PubMed: Beef liver 3-hydroxyanthranilic acid oxidase.