3-hydroxybenzaldehyde
3-formylphenol
Identification
| Name | 3-hydroxybenzaldehyde |
| CAS Number | 100-83-4 |
| EINECS | 202-892-9 |
| FDA UNII | 8Z2819J40E |
| Molecular Formula | C7 H6 O2 |
| Molecular Weight | 122.12322000 |
| MDL Number | MFCD00003368 |
| Nikkaji Number | J43.313F |
| Beilstein | 0507099 |
| XlogP3 | 1.40 (est) |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 108.00 °C. @ 760.00 mm Hg |
| Boiling Point | 240.00 °C. @ 760.00 mm Hg, 240.00 to 241.00 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure | 0.014000 mmHg @ 25.00 °C. (est) |
| Flash Point | 209.00 °F. TCC ( 98.60 °C. ) (est) |
| logP (o/w) | 1.290 |
| Soluble in | alcohol |
| Insoluble in | water |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | information only not used for fragrances or flavors |
| Recommendation for 3-hydroxybenzaldehyde usage levels up to | not for fragrance use. |
| Recommendation for 3-hydroxybenzaldehyde flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
benzaldehyde, 3-hydroxy-
meta-
formyl phenol
3-
formylphenol
m-
formylphenol
meta-
formylphenol
m-
hydroxybenzaldehyde
meta-
hydroxybenzaldehyde
PubMed:
Nontargeted GC-MS approach for volatile profile of toasting in cherry, chestnut, false acacia, and ash wood.
PubMed:
Purification and characterization of NAD+ -dependent salicylaldehyde dehydrogenase from carbaryl-degrading Pseudomonas sp. strain C6.
PubMed:
Quantum chemical studies, vibrational analysis, molecular structure, first order hyper polarizability, NBO and HOMO-LUMO analysis of 3-hydroxybenzaldehyde and its cation.
PubMed:
The first synthesis of [11C]J147, a new potential PET agent for imaging of Alzheimer's disease.
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New 1,3,4-bisthiadiazolines: synthesis, characterization and antimicrobial evaluations.
PubMed:
Thermochemical data and additivity group values for ten species of o-xylene low-temperature oxidation mechanism.
PubMed:
Growth and characterization of organic material 3-hydroxybenzaldehyde single crystal by modified vertical Bridgman technique.
PubMed:
Interference of H-bonding and substituent effects in nitro- and hydroxy-substituted salicylaldehydes.
PubMed:
Synthesis of novel biologically active heterocyclic compounds from 2-oxo-2H-benzopyran-6-yl-imidazolidine.
PubMed:
A mild conversion from 3-vinyl- to 3-formyl-chlorophyll derivatives.
PubMed:
Electrochemical, catalytic and antimicrobial activity of N-functionalized tetraazamacrocyclic binuclear nickel(II) complexes.
PubMed:
Hydrogen bond, dimerization and vibrational modes in 2-chloro-3-hydroxybenzaldehyde and 3-chloro-4-hydroxybenzaldehyde from vibrational and ab initio studies.
PubMed:
Generalized solvent scales as a tool for investigating solvent dependence of spectroscopic and kinetic parameters. Application to fluorescent BODIPY dyes.
PubMed:
Antioxidative flavonoids from Cleistocalyx operculatus buds.
PubMed:
Mutagenic, antimutagenic and antioxidant activities of a new polyphenolic and a flavonoid substances isolated from Anagallis monelli.
PubMed:
Asymmetric total synthesis of (-)-quinocarcin.
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Combinatorial synthesis and characterization of new asymmetric porphyrins as potential photosensitizers in photodynamic therapy.
PubMed:
Cytotoxic effects of 2-arylbenzofuran phytoestrogens on human cancer cells: modulation by adrenal and gonadal steroids.
PubMed:
Antioxidant and anticancer activity of 3'-formyl-4', 6'-dihydroxy-2'-methoxy-5'-methylchalcone and (2S)-8-formyl-5-hydroxy-7-methoxy-6-methylflavanone.
PubMed:
A new copper(I)-tetrahydrosalen-catalyzed asymmetric Henry reaction and its extension to the synthesis of (S)-norphenylephrine.
PubMed:
Synthesis and characterization of a novel functionalized azanonaborane cluster for boron neutron capture therapy.
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Subphthalocyanines: tuneable molecular scaffolds for intramolecular electron and energy transfer processes.
PubMed:
A benzil and isoflavone derivatives from Derris scandens Benth.
PubMed:
IR spectral and structural changes caused by the conversion of 3-hydroxybenzaldehyde into the oxyanion.
PubMed:
Effects of aldehyde dehydrogenase-2 genetic polymorphisms on metabolism of structurally different aldehydes in human liver.
PubMed:
Tetranuclear mixed-metal M(II)2Cu(II)2 complexes derived from a phenol-based macrocyclic ligand having two N(amine)2O2 and two N(imine)2O2 metal-binding sites.
PubMed:
GC/ITMS measurement of carbonyls and multifunctional carbonyls in PM2.5 particles emitted from motor vehicles.
PubMed:
3-Hydroxybenzaldehyde.
PubMed:
Methoxy-substituted 3-formyl-2-phenylindoles inhibit tubulin polymerization.
PubMed:
XH-14 analogues as adenosine antagonists.
PubMed:
Anaerobic Degradation of m-Cresol by a Sulfate-Reducing Bacterium.
PubMed:
Synthesis and biological activity of 4-amino-5-chloro-2-ethoxy-3-hydroxybenzamides, metabolites of a new gastroprokinetic agent, mosapride.
PubMed:
Bidirectional transformation of aromatic aldehydes by Desulfovibrio desulfuricans under nitrate-dissimilating conditions.
PubMed:
Spectrophotometric determination of mixtures of 2-, 3-, and 4-hydroxybenzaldehydes by flow injection analysis and uv/vis photodiode-array detection.
PubMed:
Spectrophotometric resolution of ternary mixtures of salicylaldehyde, 3-hydroxybenzaldehyde and 4-hydroxybenzaldehyde by the derivative ratio spectrum-zero crossing method.
PubMed:
TAN-931, a novel nonsteroidal aromatase inhibitor produced by Penicillium funiculosum No. 8974. II. Structure elucidation, chemical modification and biological activity.
PubMed:
Nematocidal principles in "oakmoss absolute" and nematocidal activity of 2,4-dihydroxybenzoates.
PubMed:
Kinetic spectrophotometric determination of nanogram amounts of cyanide.
PubMed:
Substrate preference of a cytosolic aldehyde dehydrogenase inducible in rat liver by treatment with 3-methylcholanthrene.
PubMed:
Liquid chromatographic determination of inhibition of monoamine oxidase activity in platelet rich plasma of depressed patients treated with phenelzine.
PubMed:
Liquid chromatographic determination of urinary metanephrines after pre-column oxidation to vanillin.
PubMed:
[Experimental observations on the iodination of phenols in the preparation of intermediates of pharmaceutical interest].
PubMed:
Conidiogenesis and secondary metabolism in Penicillium urticae.
PubMed:
Patulin biosynthesis: the metabolism of m-hydroxybenzyl alcohol and m-hydroxybenzaldehyde by particulate preparations from Penicillium patulum.