3-hydroxybenzaldehyde

3-formylphenol

CAS: 100-83-4 C7 H6 O2 MW: 122.12322000

Identification

Name3-hydroxybenzaldehyde
CAS Number100-83-4
EINECS202-892-9
FDA UNII8Z2819J40E
Molecular FormulaC7 H6 O2
Molecular Weight122.12322000
MDL NumberMFCD00003368
Nikkaji NumberJ43.313F
Beilstein0507099
XlogP31.40 (est)

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 108.00 °C. @ 760.00 mm Hg
Boiling Point 240.00 °C. @ 760.00 mm Hg, 240.00 to 241.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure 0.014000 mmHg @ 25.00 °C. (est)
Flash Point 209.00 °F. TCC ( 98.60 °C. ) (est)
logP (o/w) 1.290
Soluble in alcohol
Insoluble in water

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryinformation only not used for fragrances or flavors
Recommendation for 3-hydroxybenzaldehyde usage levels up tonot for fragrance use.
Recommendation for 3-hydroxybenzaldehyde flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

benzaldehyde, 3-hydroxy- meta- formyl phenol 3- formylphenol m- formylphenol meta- formylphenol m- hydroxybenzaldehyde meta- hydroxybenzaldehyde PubMed: Nontargeted GC-MS approach for volatile profile of toasting in cherry, chestnut, false acacia, and ash wood. PubMed: Purification and characterization of NAD+ -dependent salicylaldehyde dehydrogenase from carbaryl-degrading Pseudomonas sp. strain C6. PubMed: Quantum chemical studies, vibrational analysis, molecular structure, first order hyper polarizability, NBO and HOMO-LUMO analysis of 3-hydroxybenzaldehyde and its cation. PubMed: The first synthesis of [11C]J147, a new potential PET agent for imaging of Alzheimer's disease. PubMed: New 1,3,4-bisthiadiazolines: synthesis, characterization and antimicrobial evaluations. PubMed: Thermochemical data and additivity group values for ten species of o-xylene low-temperature oxidation mechanism. PubMed: Growth and characterization of organic material 3-hydroxybenzaldehyde single crystal by modified vertical Bridgman technique. PubMed: Interference of H-bonding and substituent effects in nitro- and hydroxy-substituted salicylaldehydes. PubMed: Synthesis of novel biologically active heterocyclic compounds from 2-oxo-2H-benzopyran-6-yl-imidazolidine. PubMed: A mild conversion from 3-vinyl- to 3-formyl-chlorophyll derivatives. PubMed: Electrochemical, catalytic and antimicrobial activity of N-functionalized tetraazamacrocyclic binuclear nickel(II) complexes. PubMed: Hydrogen bond, dimerization and vibrational modes in 2-chloro-3-hydroxybenzaldehyde and 3-chloro-4-hydroxybenzaldehyde from vibrational and ab initio studies. PubMed: Generalized solvent scales as a tool for investigating solvent dependence of spectroscopic and kinetic parameters. Application to fluorescent BODIPY dyes. PubMed: Antioxidative flavonoids from Cleistocalyx operculatus buds. PubMed: Mutagenic, antimutagenic and antioxidant activities of a new polyphenolic and a flavonoid substances isolated from Anagallis monelli. PubMed: Asymmetric total synthesis of (-)-quinocarcin. PubMed: Combinatorial synthesis and characterization of new asymmetric porphyrins as potential photosensitizers in photodynamic therapy. PubMed: Cytotoxic effects of 2-arylbenzofuran phytoestrogens on human cancer cells: modulation by adrenal and gonadal steroids. PubMed: Antioxidant and anticancer activity of 3'-formyl-4', 6'-dihydroxy-2'-methoxy-5'-methylchalcone and (2S)-8-formyl-5-hydroxy-7-methoxy-6-methylflavanone. PubMed: A new copper(I)-tetrahydrosalen-catalyzed asymmetric Henry reaction and its extension to the synthesis of (S)-norphenylephrine. PubMed: Synthesis and characterization of a novel functionalized azanonaborane cluster for boron neutron capture therapy. PubMed: Subphthalocyanines: tuneable molecular scaffolds for intramolecular electron and energy transfer processes. PubMed: A benzil and isoflavone derivatives from Derris scandens Benth. PubMed: IR spectral and structural changes caused by the conversion of 3-hydroxybenzaldehyde into the oxyanion. PubMed: Effects of aldehyde dehydrogenase-2 genetic polymorphisms on metabolism of structurally different aldehydes in human liver. PubMed: Tetranuclear mixed-metal M(II)2Cu(II)2 complexes derived from a phenol-based macrocyclic ligand having two N(amine)2O2 and two N(imine)2O2 metal-binding sites. PubMed: GC/ITMS measurement of carbonyls and multifunctional carbonyls in PM2.5 particles emitted from motor vehicles. PubMed: 3-Hydroxybenzaldehyde. PubMed: Methoxy-substituted 3-formyl-2-phenylindoles inhibit tubulin polymerization. PubMed: XH-14 analogues as adenosine antagonists. PubMed: Anaerobic Degradation of m-Cresol by a Sulfate-Reducing Bacterium. PubMed: Synthesis and biological activity of 4-amino-5-chloro-2-ethoxy-3-hydroxybenzamides, metabolites of a new gastroprokinetic agent, mosapride. PubMed: Bidirectional transformation of aromatic aldehydes by Desulfovibrio desulfuricans under nitrate-dissimilating conditions. PubMed: Spectrophotometric determination of mixtures of 2-, 3-, and 4-hydroxybenzaldehydes by flow injection analysis and uv/vis photodiode-array detection. PubMed: Spectrophotometric resolution of ternary mixtures of salicylaldehyde, 3-hydroxybenzaldehyde and 4-hydroxybenzaldehyde by the derivative ratio spectrum-zero crossing method. PubMed: TAN-931, a novel nonsteroidal aromatase inhibitor produced by Penicillium funiculosum No. 8974. II. Structure elucidation, chemical modification and biological activity. PubMed: Nematocidal principles in "oakmoss absolute" and nematocidal activity of 2,4-dihydroxybenzoates. PubMed: Kinetic spectrophotometric determination of nanogram amounts of cyanide. PubMed: Substrate preference of a cytosolic aldehyde dehydrogenase inducible in rat liver by treatment with 3-methylcholanthrene. PubMed: Liquid chromatographic determination of inhibition of monoamine oxidase activity in platelet rich plasma of depressed patients treated with phenelzine. PubMed: Liquid chromatographic determination of urinary metanephrines after pre-column oxidation to vanillin. PubMed: [Experimental observations on the iodination of phenols in the preparation of intermediates of pharmaceutical interest]. PubMed: Conidiogenesis and secondary metabolism in Penicillium urticae. PubMed: Patulin biosynthesis: the metabolism of m-hydroxybenzyl alcohol and m-hydroxybenzaldehyde by particulate preparations from Penicillium patulum.