meta-guaiacol
resorcinol methyl ether
Identification
| Name | meta-guaiacol |
| CAS Number | 150-19-6 |
| EINECS | 205-754-6 |
| FDA UNII | HXB7441U87 |
| Molecular Formula | C7 H8 O2 |
| Molecular Weight | 124.13916000 |
| MDL Number | MFCD00002267 |
| Nikkaji Number | J2.030C |
| Beilstein | 1209898 |
| XlogP3 | 1.60 (est) |
Regulatory
| DG SANTE Food Flavourings | 04.076 3-methoxyphenol |
Physical Properties
| Appearance | colorless to pale yellow clear liquid (est) |
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Specific Gravity | 1.06300 to 1.06900 @ 25.00 °C. |
| Pounds per Gallon - (est). | 8.845 to 8.895 |
| Refractive Index | 1.54700 to 1.55300 @ 20.00 °C. |
| Boiling Point | 243.00 to 244.00 °C. @ 760.00 mm Hg, 113.00 to 115.00 °C. @ 5.00 mm Hg |
| Vapor Pressure | 0.020000 mmHg @ 25.00 °C. (est) |
| Flash Point | > 230.00 °F. TCC ( > 110.00 °C. ) |
| logP (o/w) | 1.340 |
| Soluble in | alcohol |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | skin conditioning |
Organoleptic Properties
| Odor Description | at 1.00 % in dipropylene glycol. |
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | intraperitoneal-mouse LD50 320 mg/kg |
| Dermal Toxicity | skin-rat LD50 682 mg/kg |
| Inhalation Toxicity | inhalation-rat LC50 11500 gm/m3/4hours |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | cosmetic and flavor agents |
| Recommendation for meta-guaiacol usage levels up to | not for fragrance use. |
| Maximised Survey-derived Daily Intakes (MSDI-EU) | 0.011 (μg/capita/day) |
| Modified Theoretical Added Maximum Daily Intake (mTAMDI) | 420 (μg/person/day) |
| Threshold of Concern | 1800 (μg/person/day) |
| Structure Class | I |
| Dairy products, excluding products of category 02.0 (01.0) | 0.50000 |
| Fats and oils, and fat emulsions (type water-in-oil) (02.0) | 0.20000 |
| Edible ices, including sherbet and sorbet (03.0) | 0.50000 |
| Processed fruit (04.1) | 0.40000 |
| Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2) | - |
| Confectionery (05.0) | 1.00000 |
| Chewing gum (05.3) | - |
| Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0) | 0.20000 |
| Bakery wares (07.0) | 2.00000 |
| Meat and meat products, including poultry and game (08.0) | 0.20000 |
| Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0) | 0.20000 |
| Eggs and egg products (10.0) | - |
| Sweeteners, including honey (11.0) | - |
| Salts, spices, soups, sauces, salads, protein products, etc. (12.0) | 0.30000 |
| Foodstuffs intended for particular nutritional uses (13.0) | 0.50000 |
| Non-alcoholic ("soft") beverages, excl. dairy products (14.1) | 0.20000 |
| Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2) | 1.00000 |
| Ready-to-eat savouries (15.0) | 2.00000 |
| Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0) | 0.40000 |
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Potential Uses
Natural Occurrence
Synonyms
m-
guaiacol
1-
hydroxy-3-methoxybenzene
3-
hydroxyanisol
m-
hydroxyanisol
3-
hydroxyanisole
m-
hydroxyanisole
meta-
hydroxyanisole
3-
methoxy phenol
3-
methoxyphenol
m-
methoxyphenol
meta-
methoxyphenol
3-(
methyloxy)phenol
phenol, 3-methoxy-
phenol, m-methoxy-
resorcinol methyl ether
resorcinol monomethyl ether
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Association of chemically induced forestomach cell proliferation and carcinogenesis.
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CHANGES OF APPARENT IONIC MOBILITIES IN PROTOPLASM : II. THE ACTION OF GUAIACOL AS AFFECTED BY pH.
PubMed:
CHANGES OF APPARENT IONIC MOBILITIES IN PROTOPLASM : I. EFFECTS OF GUAIACOL ON VALONIA.