meta-guaiacol

resorcinol methyl ether

CAS: 150-19-6 C7 H8 O2 MW: 124.13916000

Identification

Namemeta-guaiacol
CAS Number150-19-6
EINECS205-754-6
FDA UNIIHXB7441U87
Molecular FormulaC7 H8 O2
Molecular Weight124.13916000
MDL NumberMFCD00002267
Nikkaji NumberJ2.030C
Beilstein1209898
XlogP31.60 (est)

Regulatory

DG SANTE Food Flavourings04.076 3-methoxyphenol

Physical Properties

Appearance colorless to pale yellow clear liquid (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 1.06300 to 1.06900 @ 25.00 °C.
Pounds per Gallon - (est). 8.845 to 8.895
Refractive Index 1.54700 to 1.55300 @ 20.00 °C.
Boiling Point 243.00 to 244.00 °C. @ 760.00 mm Hg, 113.00 to 115.00 °C. @ 5.00 mm Hg
Vapor Pressure 0.020000 mmHg @ 25.00 °C. (est)
Flash Point > 230.00 °F. TCC ( > 110.00 °C. )
logP (o/w) 1.340
Soluble in alcohol

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesskin conditioning

Organoleptic Properties

Odor Description at 1.00 % in dipropylene glycol.

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityintraperitoneal-mouse LD50 320 mg/kg
Dermal Toxicityskin-rat LD50 682 mg/kg
Inhalation Toxicityinhalation-rat LC50 11500 gm/m3/4hours

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorycosmetic and flavor agents
Recommendation for meta-guaiacol usage levels up tonot for fragrance use.
Maximised Survey-derived Daily Intakes (MSDI-EU)0.011 (μg/capita/day)
Modified Theoretical Added Maximum Daily Intake (mTAMDI)420 (μg/person/day)
Threshold of Concern1800 (μg/person/day)
Structure ClassI
Dairy products, excluding products of category 02.0 (01.0)0.50000
Fats and oils, and fat emulsions (type water-in-oil) (02.0)0.20000
Edible ices, including sherbet and sorbet (03.0)0.50000
Processed fruit (04.1)0.40000
Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2)-
Confectionery (05.0)1.00000
Chewing gum (05.3)-
Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0)0.20000
Bakery wares (07.0)2.00000
Meat and meat products, including poultry and game (08.0)0.20000
Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0)0.20000
Eggs and egg products (10.0)-
Sweeteners, including honey (11.0)-
Salts, spices, soups, sauces, salads, protein products, etc. (12.0)0.30000
Foodstuffs intended for particular nutritional uses (13.0)0.50000
Non-alcoholic ("soft") beverages, excl. dairy products (14.1)0.20000
Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2)1.00000
Ready-to-eat savouries (15.0)2.00000
Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0)0.40000

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Zanos Ltd.

Distributor of Speciality Chemicals and Natural Ingredients

Sourcing and supplying quality aroma chemicals and prestige natural ingredients for the flavour and fragrance industry.

View All Website +44 (0) 1565 755899 sales@zanos.co.uk

Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

m- guaiacol 1- hydroxy-3-methoxybenzene 3- hydroxyanisol m- hydroxyanisol 3- hydroxyanisole m- hydroxyanisole meta- hydroxyanisole 3- methoxy phenol 3- methoxyphenol m- methoxyphenol meta- methoxyphenol 3-( methyloxy)phenol phenol, 3-methoxy- phenol, m-methoxy- resorcinol methyl ether resorcinol monomethyl ether PubMed: Characterization of the structural determinants required for potent mechanism-based inhibition of human cytochrome P450 1A1 by cannabidiol. PubMed: Encecalol angelate, an unstable chromene from Ageratum conyzoides L.: total synthesis and investigation of its antiprotozoal activity. PubMed: Cannabidiol-2',6'-dimethyl ether, a cannabidiol derivative, is a highly potent and selective 15-lipoxygenase inhibitor. PubMed: A meta effect in nonphotochemical processes: the homolytic chemistry of m-methoxyphenol. PubMed: A functional genomics investigation of allelochemical biosynthesis in Sorghum bicolor root hairs. PubMed: Total synthesis of 10-norparvulenone and of O-methylasparvenone using a xanthate-mediated free radical addition-cyclization sequence. PubMed: Metabolic activation of 3-hydroxyanisole by isolated rat hepatocytes. PubMed: Deoxygenation of polyhydroxybenzenes: an alternative strategy for the benzene-free synthesis of aromatic chemicals. PubMed: Isolation and characterization of a veratrol:corrinoid protein methyl transferase from Acetobacterium dehalogenans. PubMed: Action mechanism of tyrosinase on meta- and para-hydroxylated monophenols. PubMed: Kinetic study of the oxidation of 3-hydroxyanisole catalysed by tyrosinase. PubMed: Oxidative and non-oxidative metabolism of 4-iodoanisole by rat liver microsomes. PubMed: New isoflavonoids as inhibitors of porcine 5-lipoxygenase. PubMed: Allergic contact dermatitis to two antioxidants in latex gloves: 4,4'-thiobis(6-tert-butyl-meta-cresol) (Lowinox 44S36) and butylhydroxyanisole. Allergen alternatives for glove-allergic patients. PubMed: Association of chemically induced forestomach cell proliferation and carcinogenesis. PubMed: CHANGES OF APPARENT IONIC MOBILITIES IN PROTOPLASM : II. THE ACTION OF GUAIACOL AS AFFECTED BY pH. PubMed: CHANGES OF APPARENT IONIC MOBILITIES IN PROTOPLASM : I. EFFECTS OF GUAIACOL ON VALONIA.