3-methyl-laevo-histidine
L-histidine, 3-methyl-
Identification
| Name | 3-methyl-laevo-histidine |
| IUPAC | (2S)-2-amino-3-(3-methylimidazol-4-yl)propanoic acid |
| CAS Number | 368-16-1 |
| EINECS | 206-704-6 |
| FDA UNII | MEH8O8Y0H0 |
| Molecular Formula | C7 H11 N3 O2 |
| Molecular Weight | 169.18407000 |
| MDL Number | MFCD00083658 |
| Nikkaji Number | J111.364J |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 2.00E+05 mg/L @ 25 °C (exp) |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for 3-methyl-laevo-histidine usage levels up to | not for fragrance use. |
| Recommendation for 3-methyl-laevo-histidine flavor usage levels up to | not for flavor use. |
BOC Sciences
Best of Chemicals Supplier
Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...
Potential Uses
Natural Occurrence
Synonyms
(2S)-2-
amino-3-(3-methylimidazol-4-yl)propanoic acid
L-
histidine, 3-methyl-
3-
methyl-L-histidine
3-
methylhistidine
PubMed:
Effects of a honeybee sting on the serum free amino acid profile in humans.
PubMed:
Carnosinases, their substrates and diseases.
PubMed:
Serum creatinine as a marker of muscle mass in chronic kidney disease: results of a cross-sectional study and review of literature.
PubMed:
Protein properties of mackerel viscera extracted by supercritical carbon dioxide.
PubMed:
O2 binding to human serum albumin incorporating iron porphyrin with a covalently linked methyl-L-histidine isomer.
PubMed:
New glycosidic derivatives of histidine-containing dipeptides with antioxidant properties and resistant to carnosinase activity.
PubMed:
Evaluating the roles of the heme a side chains in cytochrome c oxidase using designed heme proteins.
PubMed:
Concentrations of carnosine, anserine, L-histidine and 3-methyl histidine in boar spermatozoa and sheep milk by a modified HPLC method.
PubMed:
Evaluation of electron-withdrawing group effects on heme binding in designed proteins: implications for heme a in cytochrome c oxidase.
PubMed:
Glutaraldehyde (GA)-hapten adducts, but without a carrier protein, for use in a specificity study on an antibody against a GA-conjugated hapten compound: histamine monoclonal antibody (AHA-2) as a model.
PubMed:
Cobalt-mediated generation of reactive oxygen species and its possible mechanism.
PubMed:
Generation of reactive oxygen species by Co(II) from H2O2 in the presence of chelators in relation to DNA damage and 2'-deoxyguanosine hydroxylation.
PubMed:
Enhanced generation of hydroxyl radical and sulfur trioxide anion radical from oxidation of sodium sulfite, nickel(II) sulfite, and nickel subsulfide in the presence of nickel(II) complexes.
PubMed:
Mutagenicity testing of protein-containing and biological samples using the Ames/Salmonella plate incorporation test and the fluctuation test.
PubMed:
Generation of free radicals from lipid hydroperoxides by Ni2+ in the presence of oligopeptides.
PubMed:
Tumor necrosis factor induces skeletal muscle protein breakdown in rats.
PubMed:
IGF-I and the truncated analogue des-(1-3)IGF-I enhance growth in rats after gut resection.
PubMed:
Effect of systemic hyperinsulinemia on amino acid flux across human legs in postabsorptive state.
PubMed:
Effect of surgical injury and intraoperative hypothermia on whole body protein metabolism.
PubMed:
Insulin- and thyroid hormone-independent adaptation of myofibrillar proteolysis to glucocorticoids.
PubMed:
Insulin responsiveness of protein metabolism in vivo following bedrest in humans.
PubMed:
Strength conditioning in older men: skeletal muscle hypertrophy and improved function.
PubMed:
Sensitivity of myofibrillar proteins to glucocorticoid-induced muscle proteolysis.
PubMed:
Practical observations on the methodology for determining 3-methyl-l-histidine using fluorescamine derivatives.
PubMed:
Variations in the levels of 3-methyl-l-histidine of the myosins within the bovine carcass.
PubMed:
Determination of 3 methyl-L-histidine in human urine by ion exchange high performance liquid chromatography. Applications to patients in post-operative surgical care.
PubMed:
Oxidation, photosensitized by certain diketones, of enzymes and protection against such oxidation by histidine derivatives.