3-methyl-laevo-histidine

L-histidine, 3-methyl-

CAS: 368-16-1 C7 H11 N3 O2 MW: 169.18407000

Identification

Name3-methyl-laevo-histidine
IUPAC(2S)-2-amino-3-(3-methylimidazol-4-yl)propanoic acid
CAS Number368-16-1
EINECS206-704-6
FDA UNIIMEH8O8Y0H0
Molecular FormulaC7 H11 N3 O2
Molecular Weight169.18407000
MDL NumberMFCD00083658
Nikkaji NumberJ111.364J

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 2.00E+05 mg/L @ 25 °C (exp)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for 3-methyl-laevo-histidine usage levels up tonot for fragrance use.
Recommendation for 3-methyl-laevo-histidine flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

found in nature

Synonyms

(2S)-2- amino-3-(3-methylimidazol-4-yl)propanoic acid L- histidine, 3-methyl- 3- methyl-L-histidine 3- methylhistidine PubMed: Effects of a honeybee sting on the serum free amino acid profile in humans. PubMed: Carnosinases, their substrates and diseases. PubMed: Serum creatinine as a marker of muscle mass in chronic kidney disease: results of a cross-sectional study and review of literature. PubMed: Protein properties of mackerel viscera extracted by supercritical carbon dioxide. PubMed: O2 binding to human serum albumin incorporating iron porphyrin with a covalently linked methyl-L-histidine isomer. PubMed: New glycosidic derivatives of histidine-containing dipeptides with antioxidant properties and resistant to carnosinase activity. PubMed: Evaluating the roles of the heme a side chains in cytochrome c oxidase using designed heme proteins. PubMed: Concentrations of carnosine, anserine, L-histidine and 3-methyl histidine in boar spermatozoa and sheep milk by a modified HPLC method. PubMed: Evaluation of electron-withdrawing group effects on heme binding in designed proteins: implications for heme a in cytochrome c oxidase. PubMed: Glutaraldehyde (GA)-hapten adducts, but without a carrier protein, for use in a specificity study on an antibody against a GA-conjugated hapten compound: histamine monoclonal antibody (AHA-2) as a model. PubMed: Cobalt-mediated generation of reactive oxygen species and its possible mechanism. PubMed: Generation of reactive oxygen species by Co(II) from H2O2 in the presence of chelators in relation to DNA damage and 2'-deoxyguanosine hydroxylation. PubMed: Enhanced generation of hydroxyl radical and sulfur trioxide anion radical from oxidation of sodium sulfite, nickel(II) sulfite, and nickel subsulfide in the presence of nickel(II) complexes. PubMed: Mutagenicity testing of protein-containing and biological samples using the Ames/Salmonella plate incorporation test and the fluctuation test. PubMed: Generation of free radicals from lipid hydroperoxides by Ni2+ in the presence of oligopeptides. PubMed: Tumor necrosis factor induces skeletal muscle protein breakdown in rats. PubMed: IGF-I and the truncated analogue des-(1-3)IGF-I enhance growth in rats after gut resection. PubMed: Effect of systemic hyperinsulinemia on amino acid flux across human legs in postabsorptive state. PubMed: Effect of surgical injury and intraoperative hypothermia on whole body protein metabolism. PubMed: Insulin- and thyroid hormone-independent adaptation of myofibrillar proteolysis to glucocorticoids. PubMed: Insulin responsiveness of protein metabolism in vivo following bedrest in humans. PubMed: Strength conditioning in older men: skeletal muscle hypertrophy and improved function. PubMed: Sensitivity of myofibrillar proteins to glucocorticoid-induced muscle proteolysis. PubMed: Practical observations on the methodology for determining 3-methyl-l-histidine using fluorescamine derivatives. PubMed: Variations in the levels of 3-methyl-l-histidine of the myosins within the bovine carcass. PubMed: Determination of 3 methyl-L-histidine in human urine by ion exchange high performance liquid chromatography. Applications to patients in post-operative surgical care. PubMed: Oxidation, photosensitized by certain diketones, of enzymes and protection against such oxidation by histidine derivatives.