4'-aminoacetophenone

ethanone, 1-(4-aminophenyl)-

CAS: 99-92-3 C8 H9 N O MW: 135.16593000

Identification

Name4'-aminoacetophenone
CAS Number99-92-3
EINECS202-801-2
FDA UNII1S58KH902I
Molecular FormulaC8 H9 N O
Molecular Weight135.16593000
MDL NumberMFCD00007896
Nikkaji NumberJ3.228J
Beilstein0471493
XlogP30.80 (est)

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 106.00 to 107.00 °C. @ 760.00 mm Hg
Boiling Point 294.00 to 295.00 °C. @ 760.00 mm Hg
Vapor Pressure 0.002000 mmHg @ 25.00 °C. (est)
Flash Point 270.00 °F. TCC ( 132.10 °C. ) (est)
logP (o/w) 0.830
Soluble in alcohol
Insoluble in water

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityoral-rat LD50 381 mg/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryherbicides / pesticides
Recommendation for 4'-aminoacetophenone usage levels up tonot for fragrance use.
Recommendation for 4'-aminoacetophenone flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

found in nature

Synonyms

acetophenone, 4'-amino- 4- acetyl aniline 1- acetyl-4-aminobenzene 4- acetylaniline p- acetylaniline 4- amino acetophenone 1-(4- amino-phenyl)-ethanone 4- aminoacetophenone p- aminoacetophenone para- aminoacetophenone 1-(4- aminophenyl) ethanone 1-(4- aminophenyl)-ethanone 1-(4- aminophenyl)ethanone ethanone, 1-(4-aminophenyl)- PubMed: Phenylazoindole dyes--part I: the syntheses, characterizations, crystal structures, quantum chemical calculations and antimicrobial properties. PubMed: Synthesis and evaluation of changes induced by solvent and substituent in electronic absorption spectra of some azo disperse dyes. PubMed: A study of anti-inflammatory and analgesic activity of new 2,4,6-trisubstituted pyrimidines. PubMed: Synthesis and immunomodulatory activites of new 5-hydrazino-3-methyl-4-isothiazolecarboxylic acid ethyl esters. PubMed: Hydrogen bonding in the bromide salts of 4-aminobenzoic acid and 4-aminoacetophenone. PubMed: Spectroscopic and biological studies on newly synthesized nickel(II) complexes of semicarbazones and thiosemicarbazones. PubMed: Spectroscopic evaluation of manganese(II) complexes derived from semicarbazones and thiosemicarbazones. PubMed: Involvement of proton transfer in the reductive repair of DNA guanyl radicals by aniline derivatives. PubMed: Schiff bases of gossypol: an NMR and DFT study. PubMed: EPR, mass, IR, electronic, and magnetic studies on copper(II) complexes of semicarbazones and thiosemicarbazones. PubMed: Determination of thiopurine methyltransferase phenotype in isolated human erythrocytes using a new simple nonradioactive HPLC method. PubMed: Analgesic activity of thioureido derivatives of arylsemicarbazones. PubMed: Synthesis of aryl semicarbazone of 4-aminoacetophenone and their anti-HIV activity. PubMed: Formation of 4,4-dialkoxycyclohexa-2,5-dienone N-(thiol-S-yl)imine during reaction of 4-alkoxynitrosobenzenes with thiols in alcoholic solvents. PubMed: Determination of mitomycin C in human aqueous humor and serum by high-performance liquid chromatography. PubMed: Identification of aromatic moieties and mycosamine in antifungal heptaenes with high-performance liquid chromatography, high-performance liquid chromatography-mass spectrometry and gas chromatography-mass spectrometry. PubMed: Comparison of metabolism and activity of an aryldimethyltriazene and an aryldiethyltriazene. PubMed: Spectrophotometric methods for the determination of o-dihydroxybenzene derivatives. PubMed: Further application of the diazotizationcoupling spectrophotometric technique to the determination of aromatic amines with 8-amino-1 -hydroxynaphthalene-3,6-disulphonic acid and N-(1-naphthyl)-ethylenediamine as coupling agents. PubMed: Metabolism of the anticancer agent 1-(4-acetylphenyl)-3,3-dimethyltriazene. PubMed: Studies of the mode of action of antitumour triazenes and triazines--IV. The metabolism of 1-(4-acetylphenyl)-3,3-dimethyltriazene. PubMed: [Role of p-aminobenzoic acid in levorin biosynthesis]. PubMed: [Determination of p-aminoacetophenone and changes in its levels in a levorin producer depending on culture conditions]. PubMed: Location and analysis of 2-deoxy sugars on chromatograms and pherograms by fluorescence.