CAS: 94-82-6 C10 H10 Cl2 O3 MW: 249.09130000

Identification

Name2,4-DB
IUPAC4-(2,4-dichlorophenoxy)butanoic acid
CAS Number94-82-6
EINECS202-366-9
FDA UNIISL314DW868
Molecular FormulaC10 H10 Cl2 O3
Molecular Weight249.09130000
MDL NumberMFCD00002819
Nikkaji NumberJ3.948I
Beilstein1976809

Regulatory

Physical Properties

Appearance colorless crystals (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 46 mg/L @ 25 °C (exp)

No sensory data available

Safety Information

Oral/Parenteral Toxicityoral-mouse LDLo 750 mg/kg
Dermal Toxicityskin-rabbit LD50 > 10000 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryherbicides / pesticides
Recommendation for 2,4-DB usage levels up tonot for fragrance use.
Recommendation for 2,4-DB flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

butanoic acid, 4-(2,4-dichlorophenoxy)- butirex butyric acid, 4-(2,4-dichlorophenoxy)- 4-(2,4- dichlorophenoxy) butyric acid 4-(2,4- dichlorophenoxy)butanoic acid gamma-(2,4- dichlorophenoxy)butyric acid legumex D PubMed: Label-free impedimetric immunosensor for sensitive detection of 2,4-dichlorophenoxybutyric acid (2,4-DB) in soybean PubMed: Degradation of herbicide 2,4-dichlorophenoxybutanoic acid in the photolysis of [FeOH]2+ and [Fe(Ox)3]3- complexes: A mechanistic study PubMed: Characterisation of bacterial cultures enriched on the chlorophenoxyalkanoic acid herbicides 4-(2,4-dichlorophenoxy) butyric acid and 4-(4-chloro-2-methylphenoxy) butyric acid PubMed: Effects of the herbicide 2,4-DB and fungicide captan on reactions of mitochondria and chloroplasts PubMed: Degradation of 2,4-DB in Argentinean agricultural soils with high humic matter content PubMed: Adsorption and degradation of phenoxyalkanoic acid herbicides in soils: A review PubMed: Chronic dietary toxicity/oncogenicity studies on 2,4-dichlorophenoxybutyric acid in rodents PubMed: Evaluation of the in vitro genetic toxicity of 4-(2, 4-dichlorophenoxy)butyric acid PubMed: Isolation and characterization of a 2-(2,4-dichlorophenoxy) propionic acid-degrading soil bacterium PubMed: 2,4-Dichlorophenoxybutyric acid-resistant mutants of Arabidopsis have defects in glyoxysomal fatty acid beta-oxidation PubMed: Association of Macular Visual Field Measurements With Glaucoma Staging Systems PubMed: Chronic dietary toxicity study on 2,4-dichlorophenoxybutyric acid in the dog PubMed: Retinal Sensitivity Using Microperimetry in Age-Related Macular Degeneration in an Amish Population PubMed: Effect of pile-driving sounds on harbor seal (Phoca vitulina) hearing PubMed: Noise exposure and auditory thresholds of German airline pilots: a cross-sectional study PubMed: Effects of the Carrier Phrase on Word Recognition Performances by Younger and Older Listeners Using Two Stimulus Paradigms PubMed: Structure/Psychophysical Relationships in X-Linked Retinoschisis PubMed: Modification of auxinic phenoxyalkanoic acid herbicides by the acyl acid amido synthetase GH3.15 from Arabidopsis PubMed: Solid-phase extraction of acidic herbicides PubMed: Effects of accelerators on mobility of 14C-2,4-dichlorophenoxy butyric acid in plant cuticles depends on type and concentration of accelerator PubMed: Impact of reticular pseudodrusen on macular function PubMed: Sorption in reconstituted waxes of homologous series of alcohol ethoxylates and n-alkyl esters and their effects on the mobility of 2,4-dichlorophenoxybutyric acid PubMed: Bilayer Graft for Incisionless In-Office Endoscopic Repair of Tympanic Membrane Perforations: A Pilot Study PubMed: Retest Variability in the Medmont M700 Automated Perimeter PubMed: Nanoscale plasmonic TM-pass polarizer integrated on silicon photonics PubMed: The metabolism of 2,4-dibromo [6,7-3H]17 beta-oestradiol in the rat: ring-A dibromination blocks male-specific 15 alpha-hydroxylation and catechol formation PubMed: The protective effects of intratympanic dexamethasone and vitamin E on cisplatin-induced ototoxicity are demonstrated in rats PubMed: Mesopic and dark-adapted two-color fundus-controlled perimetry in patients with cuticular, reticular, and soft drusen PubMed: [A survey of the otoacoustic emissions (OAEs) of workers exposed to noise in manufacturing factories] PubMed: Human Frequency Following Response Correlates of Spatial Release From Masking PubMed: Structural characteristics of endogenous sugar acids and relations to feeding modulation PubMed: The effect of photodynamic therapy on macular sensitivity in eyes with acute central serous chorioretinopathy PubMed: Shape Optimization of an Electric Dipole Array for 7 Tesla Neuroimaging PubMed: Novel à-ketoglutarate dioxygenase tfdA-related genes are found in soil DNA after exposure to phenoxyalkanoic herbicides PubMed: Mineralization and co-metabolic degradation of phenoxyalkanoic acid herbicides by a pure bacterial culture isolated from an aquifer PubMed: Characterization of hapten-protein conjugates: antibody generation and immunoassay development for chlorophenoxyacetic acid pesticides PubMed: Predictive validity of a retrospective measure of noise exposure PubMed: Hearing levels in patients with microtia: correlation with temporal bone malformation PubMed: Uncoupled multi-core fiber enhancing signal-to-noise ratio PubMed: Predicting the Sorption of Aromatic Acids to Noncarbonized and Carbonized Sorbents PubMed: Effects of Spectral Resolution and Frequency Mismatch on Speech Understanding and Spatial Release From Masking in Simulated Bilateral Cochlear Implants PubMed: Evidence of cytochrome P450-catalyzed cleavage of the ether bond of phenoxybutyrate herbicides in Rhodococcus erythropolis K2-3 PubMed: On the mutagenic and recombinogenic activity of certain herbicides in Salmonella typhimurium and in Aspergillus nidulans PubMed: [Analysis of the sound-insulation effects of control rooms in workshops with noise] PubMed: An impedance matching algorithm for common-mode interference removal in vagus nerve recordings PubMed: Complex Gaussian Processes for Regression PubMed: Identification of two Arabidopsis genes encoding a peroxisomal oxidoreductase-like protein and an acyl-CoA synthetase-like protein that are required for responses to pro-auxins PubMed: A rapid method to screen degradation ability in chlorophenoxyalkanoic acid herbicide-degrading bacteria PubMed: Response of Retinal Sensitivity to Intravitreal Anti-angiogenic Bevacizumab and Triamcinolone Acetonide for Patients with Diabetic Macular Edema over One Year PubMed: Age-Related Hearing Loss and the Listening Environment: Communication Challenges in a Group Care Setting for Older Adults PubMed: Reduction of CPR artifacts in the ventricular fibrillation ECG by coherent line removal PubMed: Feasibility of myocardial perfusion assessment with contrast echocardiography: 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PubMed: The influence of growth hormone therapy on ultrasound myocardial tissue characterization in patients with childhood onset GH deficiency PubMed: The effect of simulated cataract on the glaucomatous visual field PubMed: A comparison of propofol- and dexmedetomidine-induced electroencephalogram dynamics using spectral and coherence analysis PubMed: Polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) impurities in pesticides: a neglected source of contemporary relevance PubMed: Myocardial integrated ultrasonic backscatter in patients with dilated cardiomyopathy: prediction of response to beta-blocker therapy PubMed: [Toxicologo-hygienic evaluation of morphological changes in the liver of animals exposed to butyl esters of 2,4-D and 2,4,5-T (2,4-DB, 2,4,5-TB) and their combinations] PubMed: Hearing in nonprofessional pop/rock musicians PubMed: Degradation of 4-(2,4-dichlorophenoxy)butyric acid (2,4-DB) by Phytophthora megasperma PubMed: Cupriavidus pampae sp. nov., a novel 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in Beijing region and effects of intervention measures] PubMed: Influence of contralateral acoustic hearing on adult bimodal outcomes after cochlear implantation PubMed: Assessment of retinal sensitivity using a time-saving strategy in normal individuals PubMed: Confirmation of transiently evoked otoacoustic emissions based on user-independent criteria PubMed: Gradient Structure Design of Flexible Waterborne Polyurethane Conductive Films for Ultraefficient Electromagnetic Shielding with Low Reflection Characteristic PubMed: Word-recognition performance in interrupted noise by young listeners with normal hearing and older listeners with hearing loss PubMed: The effect of a coding strategy that removes temporally masked pulses on speech perception by cochlear implant users PubMed: The characterization of prepared organomontmorillonite (DEDMAM) and sorption of phenoxyalkanoic acid herbicides from aqueous solution PubMed: In vitro genotoxic assessment of xenobiotic diacylglycerols in an in vitro micronucleus assay PubMed: Differences in visual function and optic nerve structure between healthy eyes of blacks and whites PubMed: Supplementation with a highly concentrated docosahexaenoic acid plus xanthophyll carotenoid multivitamin in nonproliferative diabetic retinopathy: prospective controlled study of macular function by fundus m PubMed: Automated algorithms combining structure and function outperform general ophthalmologists in diagnosing glaucoma PubMed: Progressive sensorineural hearing impairment in maternally inherited diabetes mellitus and deafness (MIDD) PubMed: Amalgam dental fillings and hearing loss PubMed: Determination of chlorinated acid herbicides in vegetation and soil by liquid chromatography/electrospray-tandem mass spectrometry PubMed: [Effects of poria cocos on ototoxicity induced by kanamycin in guinea-pigs] PubMed: Amplitude (vu and rms) and Temporal (msec) Measures of Two Northwestern University Auditory Test No. 6 Recordings PubMed: Temporal Effects on Monaural Amplitude-Modulation Sensitivity in Ipsilateral, Contralateral and Bilateral Noise PubMed: Raman-enhanced optical phase conjugator in WDM transmission systems PubMed: Vibration-induced hearing loss: mechanical and physiological aspects PubMed: Protection against ischemic cochlear damage by intratympanic administration of AM-111 PubMed: [Determination of seven phenoxyacid herbicides in environmental water by high performance liquid chromatography coupled with three phase hollow fiber liquid phase microextraction] PubMed: Retinal sensitivity measured with the micro perimeter 1 after resolution of central serous chorioretinopathy PubMed: Assessment of cerebral autoregulation with transcranial Doppler sonography in poor bone windows using constant infusion of an ultrasound contrast agent PubMed: Arabidopsis thaliana mutants disrupted in lipid mobilization PubMed: A new rapid threshold algorithm for short-wavelength automated perimetry PubMed: Prostate cancer risk and exposure to pesticides in British Columbia farmers PubMed: Effects of vocal loudness variation on spectrum balance as reflected by the alpha measure of long-term-average spectra of speech PubMed: Correlation Between Mesopic Retinal Sensitivity and Optical Coherence Tomographic Metrics of the Outer Retina in Patients With Non-Atrophic Dry Age-Related Macular Degeneration PubMed: Impact of occupational noise on pure-tone threshold and distortion product otoacoustic emissions after one workday PubMed: Detection of TIMI-3 flow before mechanical reperfusion with ultrasonic tissue characterization in patients with anterior wall acute myocardial infarction PubMed: Distortion product otoacoustic emissions in college music majors and nonmusic majors PubMed: Chemical cotton stalk destruction for maintenance of host-free periods for the control of overwintering boll weevil in tropical and subtropical climates PubMed: Barley has two peroxisomal ABC transporters with multiple functions in ?-oxidation PubMed: Estimating progression of visual field loss in glaucoma PubMed: Assessment of menopause-induced myocardial changes by integrated backscatter during inotropic stimulation and atropine injection PubMed: [Angiotensin II type 1 antagonist suppress left ventricular hypertrophy and myocardial fibrosis in patient with end stage renal disease (ESRD)] PubMed: Complexation of organic compounds in the presence of Al3+ during micellar flocculation PubMed: An Arabidopsis mutant disrupted in valine catabolism is also compromised in peroxisomal fatty acid beta-oxidation PubMed: Evaluation of the genetic activity profiles of 65 pesticides PubMed: The benefit of binaural hearing in a cocktail party: effect of location and type of interferer PubMed: A multi-slot surface coil for MRI of dual-rat imaging at 4 T PubMed: The distribution of hearing threshold levels in the general population aged 18-30 years PubMed: Calibration and uncertainties in personal exposure measurements of radiofrequency electromagnetic fields PubMed: [First experiences with a new nickel-titanium piston with a shape memory feature] PubMed: Full-duplex bidirectional data transmission link using twisted lights multiplexing over 1.1-km orbital angular momentum fiber PubMed: Hyperreflective sign in resolved cotton wool spots using high-resolution optical coherence tomography and optical coherence tomography ophthalmoscopy PubMed: A Novel Carrier Loop Algorithm Based on Maximum Likelihood Estimation (MLE) and Kalman Filter (KF) for Weak TC-OFDM Signals PubMed: Congruent tactile stimulation reduces the strength of visual suppression during binocular rivalry PubMed: Microperimetric retinal changes in myopic choroidal neovascularization treated with intravitreal ranibizumab PubMed: Dynamics of hepatic steatosis resolution and changes in gut microbiome with weight loss in nonalcoholic fatty liver disease PubMed: Using a Digital Language Processor to Quantify the Auditory Environment and the Effect of Hearing Aids for Adults with Hearing Loss PubMed: Gas chromatographic/electron capture detection method for determination of chlorinated acids in water: collaborative study PubMed: The average specific forced radiation wave impedance of a finite rectangular panel PubMed: Course of hearing loss and occurrence of tinnitus PubMed: [Agreement and correlation between the frequency doubling perimetry and the blue-yellow perimetry in glaucoma: no support for selective damage] PubMed: Silicon arrayed waveguide gratings at 2.0-?m wavelength characterized with an on-chip resonator PubMed: Analysis of fifty-six cochlear implant device failures PubMed: Audiological results of the bone-anchored hearing aid HC200: multicenter results PubMed: Multimode optomechanical system in the quantum regime PubMed: Calmodulin-like protein AtCML3 mediates dimerization of peroxisomal processing protease AtDEG15 and contributes to normal peroxisome metabolism PubMed: Test-retest reliability of the Toy Discrimination Test with a masker of noise or babble in children with hearing impairment PubMed: A new technique for measurement of water permeability of stomatous cuticular membranes isolated from Hedera helix leaves PubMed: Compressed sensing MRI via two-stage reconstruction PubMed: Effects of temperature and concentration of the accelerators ethoxylated alcohols, diethyl suberate and tributyl phosphate on the mobility of [14C]2,4-dichlorophenoxy butyric acid in plant cuticles PubMed: Clinical performance of a highly portable, scanning calcaneal ultrasonometer PubMed: Speech perception and talker segregation: effects of level, pitch, and tactile support with multiple simultaneous talkers PubMed: Repeatability of distortion product otoacoustic emissions in normally hearing humans PubMed: Within-test variability of frequency-doubling perimetry using a 24-2 test pattern PubMed: Evaluation of acoustical parameter sensitivity to age-related and osteoarthritic changes in articular cartilage using 50-MHz ultrasound PubMed: Sphingomonas herbicidovorans MH: a versatile phenoxyalkanoic acid herbicide degrader PubMed: Myocardial tissue characterization in heart failure by real-time integrated backscatter PubMed: Effect of stimulus duration on stapedius reflex threshold in electrical stimulation via cochlear implant PubMed: Evaluation of a pinna compensation algorithm for sound localization and speech perception in noise PubMed: Effects of Herbicides on Sclerotinia Crown and Stem Rot of Alfalfa PubMed: [Fe(Ox)(3)](3-) complex as a photodegradation agent at neutral pH: Advances and limitations PubMed: Cyclic variation of integrated ultrasound backscatter: normal and abnormal myocardial patterns in children PubMed: Hearing deterioration in patients with a non-growing vestibular schwannoma PubMed: Quantitative relationship of carboplatin dose to magnitude of inner and outer hair cell loss and the reduction in distortion product otoacoustic emission amplitude in chinchillas PubMed: Impact of basic fibroblast growth factor on healing of tympanic membrane perforations due to direct penetrating trauma: a prospective non-blinded/controlled study PubMed: Establishing the feasibility of coupled solid-phase extraction-solid-phase derivatization for acidic herbicides PubMed: Fatty acid beta-oxidation in germinating Arabidopsis seeds is supported by peroxisomal hydroxypyruvate reductase when malate dehydrogenase is absent PubMed: Mutations in the Arabidopsis peroxisomal ABC transporter COMATOSE allow differentiation between multiple functions in planta: insights from an allelic series PubMed: Monitoring the Hearing Handicap and the Recognition Threshold of Sentences of a Patient with Unilateral Auditory Neuropathy Spectrum Disorder with Use of a Hearing Aid PubMed: Structural and functional changes associated with normal and abnormal fundus autofluorescence in patients with retinitis pigmentosa PubMed: Azimuthal sound localization in the European 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Physical binaural cues PubMed: The Natural Course of Tympanic Membrane Retractions in the Posterosuperior Quadrant of Pars Tensa: A Watchful Waiting Policy PubMed: A clinical comparison between a laboratory and a commercial impedance audiometer PubMed: Ultrasensitive two-mode interferometry with single-mode number squeezing PubMed: Randomized, prospective, three-arm study to confirm the auditory safety and efficacy of artemether-lumefantrine in Colombian patients with uncomplicated Plasmodium falciparum malaria PubMed: Diagnosis of recent myocardial infarction with quantitative backscatter imaging: preliminary studies PubMed: The changes in acoustic attenuation due to in vitro heating PubMed: Simultaneous determination of acidic and non-acidic pesticides in natural waters by liquid chromatography-mass spectrometry PubMed: Efficient and mode selective spatial mode multiplexer based on multi-plane light conversion PubMed: Echelle grating silicon multi/demultiplexers with 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in bands of modulated or unmodulated noise PubMed: Spin squeezing of a cold atomic ensemble with the nuclear spin of one-half PubMed: Sample preparation based on dynamic ion-exchange solid-phase extraction for GC/MS analysis of acidic herbicides in environmental waters PubMed: Characteristics of stapedius muscle electromyograms elicited by cochlear implant stimulation in the rat PubMed: Acoustically coupled thickness-mode AIN-on-Si band-pass filters--part I: principle and devices PubMed: Achieving the shot-noise limit using experimental multi-shot digital holography data PubMed: Capabilities and limitations of dispersive liquid-liquid microextraction with solidification of floating organic drop for the extraction of organic pollutants from water samples PubMed: Optimizing the subcarrier granularity of coherent optical communications systems PubMed: Effects of signal duration on the recognition of masked communication signals by the grasshopper Chorthippus biguttulus PubMed: Modeling 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