4-aminophenyl acetic acid
4-aminophenylacetic acid
Identification
| Name | 4-aminophenyl acetic acid |
| IUPAC | 2-(4-aminophenyl)acetic acid |
| CAS Number | 1197-55-3 |
| EINECS | 214-828-7 |
| FDA UNII | 1IED47A544 |
| Molecular Formula | C8 H9 N O2 |
| Molecular Weight | 151.16513000 |
| MDL Number | MFCD00007916 |
| Nikkaji Number | J27.580H |
| Beilstein | 2208094 |
| XlogP3 | 0.90 (est) |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 200.00 °C. @ 760.00 mm Hg |
| Boiling Point | 344.00 °C. @ 760.00 mm Hg (est) |
| Flash Point | 323.00 °F. TCC ( 161.90 °C. ) (est) |
| logP (o/w) | 0.220 (est) |
| Soluble in | water, 6.811e+004 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | intraperitoneal-mouse LD50 3500 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | pharmaceuticals / chemical synthisis |
| Recommendation for 4-aminophenyl acetic acid usage levels up to | not for fragrance use. |
| Recommendation for 4-aminophenyl acetic acid flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
acetic acid, (p-aminophenyl)-
p-
amino-alpha-toluic acid
4-
aminobenzeneacetic acid
(p-
aminophenyl)acetic acid
(para-
aminophenyl)acetic acid
2-(4-
aminophenyl)acetic acid
4-
aminophenylacetic acid
p-
aminophenylacetic acid
benzeneacetic acid, 4-amino-
PubMed:
[Synthesis and PPAR activities of novel phenylacetic acid derivatives containing sulfonamide moiety].
PubMed:
Production of the polyclonal antibody against Sudan 3 and Immunoassay of Sudan dyes in food samples.
PubMed:
Synthesis of mutual azo prodrugs of anti-inflammatory agents and peptides facilitated by α-aminoisobutyric acid.
PubMed:
p-Aminophenylacetic acid-mediated synthesis of monodispersed titanium oxide hybrid microspheres in ethanol solution.
PubMed:
Preparation of 4-aminophenylacetic acid derivatives with promising antimicrobial activity.
PubMed:
Activation of vagal afferents in the rat duodenum by protein digests requires PepT1.
PubMed:
Inhibition of Clostridium difficile toxin A-induced colitis in rats by APAZA.
PubMed:
4-aminomethylbenzoic acid is a non-translocated competitive inhibitor of the epithelial peptide transporter PepT1.
PubMed:
Peptide mimics as substrates for the intestinal peptide transporter.
PubMed:
[STUDIES ON MONOAMINE OXIDASE INHIBITORS. IV. 4-AMINOPHENYLACETIC ACID HYDRAZIDE DERIVATIVES].