Identification

Nameacetophenone
IUPAC1-phenylethanone
CAS Number98-86-2
EINECS202-708-7
FDA UNIIRK493WHV10
Molecular FormulaC8 H8 O
Molecular Weight120.15096000
MDL NumberMFCD00008724
Nikkaji NumberJ3.225E
Beilstein0605842
CoE Number138
XlogP31.60 (est)

Regulatory

JECFA Food Flavoring806 acetophenone
DG SANTE Food Flavourings07.004 acetophenone
FEMA Number2009
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)98-86-2 ; ACETOPHENONE
FDA RegulationFDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION

Physical Properties

Appearance colorless to pale yellow clear liquid but solid at low temps (est)
Assay 98.00 to 100.00
Food Chemicals Codex Listed Yes
Specific Gravity 1.02500 to 1.03200 @ 25.00 °C.
Pounds per Gallon - (est). 8.529 to 8.587
Refractive Index 1.53300 to 1.53600 @ 20.00 °C.
Melting Point 19.00 to 20.00 °C. @ 760.00 mm Hg
Boiling Point 202.00 to 203.00 °C. @ 760.00 mm Hg, 114.00 to 115.00 °C. @ 50.00 mm Hg
Congealing Point 19.30 °C.
Vapor Pressure 0.397000 mmHg @ 25.00 °C.
Vapor Density 4.1 ( Air = 1 )
Flash Point 179.00 °F. TCC ( 81.67 °C. )
logP (o/w) 1.580
Shelf Life 24.00 month(s) or longer if stored properly.
Storage store in cool, dry place in tightly sealed containers, protected from heat and light.
Soluble in chloroform
Insoluble in water
Stability non-discoloring in most media
Similar Items note

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesfragrance

Organoleptic Properties

Odor Strength high ,
Substantivity 7 hour(s) at 100.00 %
Odor Description
at 1.00 % in dipropylene glycol.
at 1.00 %.
very intensive, sweet, floral, acacia, hawthorn
Very Sweet, Pungent, Aromatic, Floral
aromatic, spicy (almond, nuts), fruity (cherry, strawberry)
Odor sample from Givaudan Corporation
Taste Description
at 3.50 - 10.00 ppm.
almond phenolic
spicy, fruity

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Human Experience2 % solution: no irritation or sensitization.
Oral/Parenteral Toxicitygavage-rat LD50 [sex: M] 3000 mg/kg
Dermal Toxicityskin-rabbit LD50 15900 ul/kg
Inhalation Toxicityinhalation-rat LC50 > 210 ppm/8H

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavor and fragrance agents
RIFM Fragrance Material Safety AssessmentSearch
Recommendation for acetophenone usage levels up to2.0000 % in the fragrance concentrate.
Maximised Survey-derived Daily Intakes (MSDI-EU)15.00 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA)170.00 (μg/capita/day)
Threshold of Concern1800 (μg/person/day)
Structure ClassI
baked goods-
beverages(nonalcoholic)-
beverages(alcoholic)-
breakfast cereal-
cheese-
chewing gum0.60000
condiments / relishes-
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy-
fruit ices-
gelatins / puddings-
granulated sugar-
gravies-
hard candy-
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-

Advanced Biotech. Inc.

Inspired by Nature

A diverse range of products, all meeting our stringent commitment to quality.

View All Website 973-339-6242 info@adv-bio.com

Alfrebro LLC/ Archer Daniels Midland Company

Let's get reacquainted

Building great taste with aroma chemicals, extracts, and distillates

View All Website 513-539-7373 sforbis@alfrebro.com

Augustus Oils Ltd

The Premier Supplier

Augustus Oils Ltd, in harmony with nature - to present it at its best...

View All Website +44 (0)1420 590555 essentials@augustus-oils.ltd.uk

Axxence Aromatic GmbH

We bring nature to your flavour

Dedicated to provide the best possible quality and supply service of natural aroma ingredients.

View All Website +49.2822.68561.0 service@axxence.com

Berje Inc.

Where the world comes to its senses

Where the world comes to its senses - Berjé is a global distributor of Essential Oils and Aromatic Chemicals.

View All Website 973-748-8980 tlauzurica@berjeinc.com

BOC Sciences

Best of Chemicals Supplier

Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...

View All Website 1-631-485-4226 account@bocsci.com

CJ Latta & Associates, LLC

Extensive Line

Aromatic Chemicals and Organic Acids.

View All Website (630) 240-8079 chiplatta@msn.com

Excellentia International

Ingredients by Nature

Exceptional quality and excellence in meeting our customers requirements.

View All Website 732.749.9840 info@excellentiaint.com

Glentham Life Sciences Ltd

The Chemical, Biochemical & Research Essentials Supplier

Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK.

View All Website +44 (0) 1225 667798 info@glentham.com

Global Essence Inc.

Preferred Partner

Accommodate each customers unique needs.

View All Website 001 732 677 1100 info@globalessenceuk.com

H. Interdonati, Inc.

Innovative products

Because your flavors and fragrances are only as good as their source "Since 1952"

View All Website 800 367-6617 flavorplus@hinterdonati.com

Indukern, S.A. F&F Ingredients Division

Commitment to quality

Idukern F&F Ingredients is your partner for the fragrance and flavor ingredients.

View All Website +34 93 506 91 00 info@indukern.es

Lluch Essence S.L.

A family company dedicated to sales and distribution

Flexibility, availability, price and quality.

View All Website 34 93 379 38 49 web@lluche.com

M&U International LLC

Steady supply & demand

Meeting customers increasing demands at home as well as abroad.

View All Website 908-359-9000 sales@mu-intel.com

Moellhausen S.P.A.

THE CHEMISTRY OF EMOTIONS

Innovation and commitment in the name of excellence.

View All Website +39 039.685.6262

Natural Advantage

Manufacturer of natural flavor ingredients

With over 25 years experience in the flavor and food ingredient industries.

View All Website 318-215-1456 info@natadv.com

Penta International Corporation

Chemistry innovation

At Penta, our products and services help businesses do business better.

View All Website (973) 740-2300 lisaa@pentamfg.com

PerfumersWorld Ltd.

feeeel... the smell!

The one-stop resource for the creative perfumer.

View All Website +66(0)2-99-800-80 pwenquiries@perfumersworld.com

Riverside Aromatics Ltd.

Speciality Aroma Chemicals, Naturals and Synthetics

A specialist supplier of raw materials to the flavour industry.

View All Website +44 (0) 1202 679532 info@riversidearomatics.com

Sigma-Aldrich

Complete Supply Chain

The perfect blend of products and services that bring your creativity to life.

View All Website 800-244-1173 ff@sial.com

SRS Aromatics Ltd

For over 25 years

Bringing flavour and fragrance into your world.

View All Website +44 (0) 1284 704076 info@srsaromatics.co.uk

Symrise AG

Always Insiring More

Symrise aroma molecules & cosmetic ingredients for unique and innovative fragrances, flavors and cosmetics.

View All Website +49 5531 90 0 scentandcare@symrise.com

Synerzine, Inc.

Innovation. Customization. Aroma Ingredients.

Synerzine is a leading supplier of flavor and fragrance ingredients.

View All Website (404) 524-6744 info@synerzine.com

Taytonn ASCC Pte Ltd

Supplying Asia Pacific

We fully understand the demands of the F&F industry and we endeavour to supply quality products, with ready availability and a personalised service.

View All Website + 65 - 6861 8113 info@taytonnascc.com

TCI AMERICA

Moving Your Chemistry Forward

We continuously strive to advance our technology.

View All Website 1-800-423-8616 Sales-US@TCIchemicals.com;

The John D. Walsh Company, Inc

Suppliers Since 1942

Supplying the fragrance and flavor industry with high quality products.

View All Website 973-962-1400 info@johndwalsh.com

The Lermond Company

Your Sourcing Resource

The Lermond family has been sourcing raw materials for the flavor and fragrance industry for nearly 7 decades.

View All Website 201-896-3300 info@lermond.com

R C Treatt and Co Ltd

Innovative ingredient solutions

World-leading innovative ingredient solutions provider for the flavour, fragrance and FMCG industries.

View All Website +1 863 668 9500 enquiries@treatt.com

Ernesto Ventós S.A.

Leaders in essence

We employ our five senses to do our job well.

View All Website +1 856 226 7501 info@ventos.com

Vigon International

Passion for Simplicity

Manufacturer and supplier of high quality flavor and fragrance ingredients.

View All Website 570-476-6300 sales@vigon.com

Potential Uses

FR acacia FR almond FR amber FL beef roasted beef FR bubble gum FR butterscotch FR castoreum FR cherry FL chocolate cocoa FR cranberry FR fern FR floral FR hawthorn FR hay new mown hay FR herbal FR labdanum FR lavender FR leather russian leather FR lemon FR lilac FR mimosa FL nut FR orris FR rose FR strawberry FR tea green tea FR tobacco FR wisteria FR woodruff

Natural Occurrence

beef roasted beef 401 ppm PMC castoreum absolute PMC castoreum extract PMC celery seed chicory root cistus oil @ 0.1% Data clove fruit cocoa 463 ppm cranberry fruit 5 ppm elsholtzia argyi var. nipponica elsholtzia citiata grape concord grape PMC guava leaf oil cuba @ trace% Data labdanum leaf oil @ 0.20% Data o. citraliferum PMC o. linalooliferum var. laerolinalooliferum PMC o. sabinotiferum var. taiwanense PMC orris PMC orthodon species PMC pea green pea PMC pepper black pepper fruit oil plum fruit PMC plumcot fruit PMC populus balsaifera raspberry red raspberry fruit rugula herb salvia plebeia oil @ 0.21% Data spearmint oil stirlingia latifolia 90% strawberry wild strawberry fruit 11 ppm tea green tea tea plant vassoura oil @ 0.20% Data watermelon fruit juice

Synonyms

acetofenon acetophenone FCC acetophenone natural acetophenone PG acetophenone prime acetyl benzene acetyl benzol acetylbenzene acetylbenzol benzoyl methide benzoylmethide ethanone, 1-phenyl- hypnon hypnone ketone, methyl phenyl methyl phenyl ketone methylphenyl ketone 1- phenyl ethanone phenyl methyl ketone 1- phenyl-1-ethanone oxo phenylethane 1- phenylethanone phenylmethylketone US Patents: 3,952,024 - Furfurylthioacetone PubMed: The measurement of analyte diffusion from hydrogel microcapsules in model aqueous environments. US Patents: 3,931,166 - Certain 2,5-dimethyl-3-thiopyrazines PubMed: Oxidation of acetophenone by Aspergillus species and their possible contribution to Katsuobushi flavor. PubMed: Bioconversion of cinnamic Acid to acetophenone by a pseudomonad: microbial production of a natural flavor compound. PubMed: The measurement of analyte diffusion from hydrogel microcapsules in model aqueous environments. PubMed: Characterization of the most odor-active compounds in an American Bourbon whisky by application of the aroma extract dilution analysis. PubMed: Comparison of key aroma compounds in cooked brown rice varieties based on aroma extract dilution analyses. PubMed: Parental olfactory experience influences behavior and neural structure in subsequent generations. PubMed: Molecular vibration-sensing component in human olfaction. PubMed: Genetic variation in odorant receptors contributes to variation in olfactory behavior in a natural population of Drosophila melanogaster. PubMed: Chemical composition of burnt smell caused by accidental fires: environmental contaminants. PubMed: Mice with a "monoclonal nose": perturbations in an olfactory map impair odor discrimination. PubMed: Learning-dependent structural plasticity in the adult olfactory pathway. PubMed: Defining the typical aroma of sherry vinegar: sensory and chemical approach. PubMed: Characterization of the most odor-active compounds in an American Bourbon whisky by application of the aroma extract dilution analysis. PubMed: A floral-derived compound attractive to the tephritid fruit fly parasitoid Diachasmimorpha longicaudata (Hymenoptera: Braconidae). PubMed: Olfactory epithelia exhibit progressive functional and morphological defects in CF mice. PubMed: Analytical determination of the suitability of different processes for the treatment of odorous waste gas. PubMed: Olfactory-mediated fear conditioning in mice: simultaneous measurements of fear-potentiated startle and freezing. PubMed: Dendritic stability in the adult olfactory bulb. PubMed: Comparison of key aroma compounds in cooked brown rice varieties based on aroma extract dilution analyses. PubMed: Orbital cortex neuronal responses during an odor-based conditioned associative task in rats. PubMed: Odor response properties of rat olfactory receptor neurons. PubMed: Diurnal variations in olfactory sensitivity and the relationship to food intake.