4-methoxysalicylic acid

benzoic acid, 2-hydroxy-4-methoxy-

CAS: 2237-36-7 C8 H8 O4 MW: 168.14856000

Identification

Name4-methoxysalicylic acid
IUPAC2-hydroxy-4-methoxybenzoic acid
CAS Number2237-36-7
EINECS218-801-0
FDA UNIISearch
Molecular FormulaC8 H8 O4
Molecular Weight168.14856000
MDL NumberMFCD00002450
Nikkaji NumberJ213.133A
XlogP32.00 (est)

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 328.70 °C. @ 760.00 mm Hg (est)
Flash Point 280.00 °F. TCC ( 137.90 °C. ) (est)
logP (o/w) 2.240 (est)
Soluble in water, 2463 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for 4-methoxysalicylic acid usage levels up tonot for fragrance use.
Recommendation for 4-methoxysalicylic acid flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

decalepis arayalpathra root evening-primrose plant

Synonyms

benzoic acid, 2-hydroxy-4-methoxy- 2- hydroxy-4-methoxybenzoic acid PubMed: Synthesis, biological evaluation and molecular docking studies of 1,3,4-oxadiazole derivatives as potential immunosuppressive agents. PubMed: [Chemical constituents from root barks of Periploca sepium]. PubMed: Polyphenolic compounds from Platycodon grandiflorum A. DC. PubMed: Two pyranocoumarins from the seeds of Calophyllum polyanthum. PubMed: Metabolism of the 18O-methoxy substituent of 3-methoxybenzoic acid and other unlabeled methoxybenzoic acids by anaerobic bacteria.