4-pyridine carboxaldehyde

isonicotinaldehyde

CAS: 872-85-5 C6 H5 N O MW: 107.11205000 fruity

Identification

Name4-pyridine carboxaldehyde
IUPACpyridine-4-carbaldehyde
CAS Number872-85-5
EINECS212-832-3
FDA UNIISearch
Molecular FormulaC6 H5 N O
Molecular Weight107.11205000
MDL NumberMFCD00006425
Nikkaji NumberJ28.013E
Beilstein0105342
XlogP30.40 (est)

Regulatory

Physical Properties

Appearance colorless to pale yellow clear liquid (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 1.13700 to 1.14200 @ 20.00 °C.
Pounds per Gallon - (est). 9.472 to 9.514
Refractive Index 1.54200 to 1.54600 @ 20.00 °C.
Melting Point -4.00 °C. @ 760.00 mm Hg
Boiling Point 187.00 °C. @ 760.00 mm Hg, 192.00 to 193.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure 0.242000 mmHg @ 25.00 °C. (est)
Flash Point 130.00 °F. TCC ( 54.44 °C. )
logP (o/w) 0.430
Soluble in water, 4.774e+004 mg/L @ 25 °C (est)

Organoleptic Properties

Taste Description fruity

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityoral-mouse LDLo 1600 mg/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryinformation only not used for fragrances or flavors
Recommendation for 4-pyridine carboxaldehyde usage levels up tonot for fragrance use.
Recommendation for 4-pyridine carboxaldehyde flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

4- formylpyridine p- formylpyridine iso nicotinaldehyde iso nicotinic aldehyde 4- pyridine aldehyde pyridine-4-aldehyde pyridine-4-carbaldehyde pyridine-4-carboxaldehyde pyridine-4-ylcarboxaldehyde 4- pyridinealdehyde p- pyridinealdehyde 4- pyridinecarboxaldehyde (4- pyridinecarboxaldehyde) 4- pyridylaldehyde US Patents: 3,952,024 - Furfurylthioacetone PubMed: The involvement of P2Y12 receptors, NADPH oxidase, and lipid rafts in the action of extracellular ATP on synaptic transmission at the frog neuromuscular junction. US Patents: Certain 2,5-dimethyl-3-thiopyrazines PubMed: [Live cell fluorescent imaging and cytotoxicity assessment of pH fluorescent probe based on styrylcyanine dyes]. PubMed: Heterogeneous carbon gels: N-doped carbon xerogels from resorcinol and N-containing heterocyclic aldehydes. PubMed: Biaryl amides and hydrazones as therapeutics for prion disease in transgenic mice. PubMed: Comparative studies of structural, thermal, optical, and electrochemical properties of azines with different end groups with their azomethine analogues toward application in (opto)electronics. PubMed: A novel ruthenium(II)-cobaloxime supramolecular complex for photocatalytic H2 evolution: synthesis, characterisation and mechanistic studies. PubMed: The binding of β-d-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: A new class of inhibitors. PubMed: Preparation and characterization of N-heterocyclic chitosan derivative based gels for biomedical applications. PubMed: Excitation-energy dependence of the phosphorescence quantum yields of pyridinecarboxaldehyde vapors. PubMed: Probing lead(II) bonding environments in 4-substituted pyridine adducts of (2,6-Me2C6H3S)2Pb: an X-ray structural and solid-state 207Pb NMR study. PubMed: Emission spectra and electronic energy levels of the rotational isomers of pyridinecarboxaldehyde vapors. PubMed: Enhancement of metal-metal coupling at a considerable distance by using 4-pyridinealdazine as a bridging ligand in polynuclear complexes of rhenium and ruthenium. PubMed: Noncentrosymmetric organic solids with very strong harmonic generation response. PubMed: Dibromo(pyridoxal semicarbazone-kappa3N1,O3,O3')copper(II). PubMed: Pillared, 3D metal-organic frameworks with rectangular channels. Synthesis and characterization of coordination polymers based on tricadmium carboxylates. PubMed: Synthesis and calcium channel-modulating effects of alkyl (or cycloalkyl) 1,4-dihydro-2,6-dimethyl-3-nitro-4-pyridyl-5-pyridinecarboxylate racemates and enantiomers. PubMed: Large Molecular Quadratic Hyperpolarizabilities in Donor/Acceptor-Substituted trans-Tetraammineruthenium(II) Complexes. PubMed: Syntheses, calcium channel agonist-antagonist modulation activities, and voltage-clamp studies of isopropyl 1,4-dihydro-2,6-dimethyl-3-nitro-4-pyridinylpyridine-5-carboxylate racemates and enantiomers. PubMed: Aromatase inhibitors. Syntheses and structure-activity studies of novel pyridyl-substituted indanones, indans, and tetralins. PubMed: New aromatase inhibitors. Synthesis and biological activity of pyridyl-substituted tetralone derivatives. PubMed: Relationship between structure and antineoplastic activity of (arylsulfonyl)hydrazones of 4-pyridinecarboxaldehyde. PubMed: The binding affinity of amphetamine to 4-pyridinecarboxaldehyde and the coenzymes pyridoxal and pyridoxal-5-phosphate. PubMed: [Reactivation of phosphorylated acetylcholinesterase (AChE): quaternary salts of vinylogous pyridinaldoxims (author's transl)]. PubMed: [Quantitative determination of alkylating cytostatics on TLC plate with 4-pyridinecarboxaldehyde-2-benzothiazolylhydrazone]. PubMed: 5-(2-Chloroethyl)-3-hydroxy-2-methyl-4-pyridinecarboxaldehyde ( 5 -pyridoxal methyl chloride) and its reaction with N -acetyl-L-lysine to form a new cyclic imino acid derivative of homopyridoxal. PubMed: Xanthine oxidase catalyzed oxidation of aldehydes. Oxidation of aliphatic aldehydes and 2- and 4-pyridinecarboxaldehyde. PubMed: Photoinactivation of aldolases by pyridoxal phosphate and its analogues.