4-hydroxymethyl-pyridine
4-pyridylcarbinol
Identification
| Name | 4-hydroxymethyl-pyridine |
| IUPAC | pyridin-4-ylmethanol |
| CAS Number | 586-95-8 |
| EINECS | 209-590-6 |
| FDA UNII | Search |
| Molecular Formula | C6 H7 N O |
| Molecular Weight | 109.12799000 |
| MDL Number | MFCD00006442 |
| Nikkaji Number | J85.689D |
| Beilstein | 107850 |
| XlogP3 | 0.10 (est) |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 53.00 °C. @ 760.00 mm Hg |
| Vapor Pressure | 0.026000 mmHg @ 20.00 °C. |
| Flash Point | > 230.00 °F. TCC ( > 110.00 °C. ) |
| logP (o/w) | 0.060 |
| Soluble in | water, 1.00E+06 mg/L @ 20 °C (exp) |
Organoleptic Properties
| Taste Description | hazelnut- coffee-like |
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | oral-bird - wild LD50 422 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | information only not used for fragrances or flavors |
| Recommendation for 4-hydroxymethyl-pyridine usage levels up to | not for fragrance use. |
| Recommendation for 4-hydroxymethyl-pyridine flavor usage levels up to | not for flavor use. |
BOC Sciences
Best of Chemicals Supplier
Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...
Glentham Life Sciences Ltd
The Chemical, Biochemical & Research Essentials Supplier
Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK.
Potential Uses
Natural Occurrence
Synonyms
4-
hydroxymethyl pyridine
4-(
hydroxymethyl)pyridine
4-
hydroxymethylpyridine
4-
picolyl alcohol
gamma-
picolyl alcohol
4-
pyridin-4-ylmethanol
4-
pyridinecarbinol
4-
pyridinemethanol
4-
pyridyl carbinol
4-
pyridylcarbinol
4-
pyridylmethanol
US Patents:
3,952,024 - Furfurylthioacetone
PubMed:
The role of p53 in the cellular toxicity by active trans-platinum complexes containing isopropylamine and hydroxymethylpyridine.
US Patents:
Certain 2,5-dimethyl-3-thiopyrazines
PubMed:
Study by HPLC-MS of the interaction of platinum antitumor complexes with potato carboxypeptidase inhibitor (PCI).
PubMed:
Influence of the position of substituents in the cytotoxic activity of trans platinum complexes with hydroxymethyl pyridines.
PubMed:
Selective intracellular accumulation of the major metabolite issued from the activation of the prodrug ethionamide in mycobacteria.
PubMed:
Chelation-assisted transformation: synthesis of 1,4-dicarboxylate esters by the Rh-catalyzed carbonylation of internal alkynes with pyridin-2-ylmethanol.
PubMed:
Synthesis and anti-HIV-1 and anti-HCMV activity of 1-substituted 3-(3,5-dimethylbenzyl)uracil derivatives.
PubMed:
Recognition of DNA modified by trans-[PtClNH(4-hydroxymethylpyridine)] by tumor suppressor protein p53 and character of DNA adducts of this cytotoxic complex.
PubMed:
Synthesis, characterization and biological activity of trans-platinum(II) and trans-platinum(IV) complexes with 4-hydroxymethylpyridine.
PubMed:
The thermal and light induced spin transition in [FeL2](BF4)2 (L = 2,6-dipyrazol-1-yl-4-hydroxymethylpyridine).
PubMed:
On the formation of isopropylidenepyridoxines. A convenient method for the preparation of 2,2,8-trimethyl-4H-1,3-dioxino[4,5-c]pyridin-5-ylmethanol from pyridoxine hydrochloride.
PubMed:
[Pharmacodynamic study of (M-14012-4) N-(4-picolyl)-3,5-dimethylbenzamide].