2,4,5-trimethoxybenzaldehyde
benzaldehyde, 2,4,5-trimethoxy-
Identification
| Name | 2,4,5-trimethoxybenzaldehyde |
| IUPAC | 2,4,5-trimethoxybenzaldehyde |
| CAS Number | 4460-86-0 |
| EINECS | 224-713-3 |
| FDA UNII | NDU8J2Q00D |
| Molecular Formula | C10 H12 O4 |
| Molecular Weight | 196.20244000 |
| MDL Number | MFCD00003312 |
| Nikkaji Number | J13.494E |
| Beilstein | 1951403 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 112.00 to 114.00 °C. @ 760.00 mm Hg |
| Boiling Point | 334.00 to 335.00 °C. @ 760.00 mm Hg (est), 140.00 °C. @ 4.00 mm Hg |
| Vapor Pressure | 0.000125 mmHg @ 25.00 °C. (est) |
| Flash Point | 300.00 °F. TCC ( 149.00 °C. ) (est) |
| logP (o/w) | 1.634 (est) |
| Soluble in | ether |
| Insoluble in | water |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | oral-bird - wild LD50 422 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for 2,4,5-trimethoxybenzaldehyde usage levels up to | not for fragrance use. |
| Recommendation for 2,4,5-trimethoxybenzaldehyde flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
asaraldehyde
asaronaldehyde
asarone aldehyde
azaryl aldehyde
azarylaldehyde
benzaldehyde, 2,4,5-trimethoxy-
gazarin
2,4,5-
trimethoxy benzaldehyde
2,4,5-
trimethoxy-benzaldehyde
2,4,5-
trimethoxybenzaldehdye
PubMed:
Activity of chalcones derived from 2,4,5-trimethoxybenzaldehyde against Meloidogyne exigua and in silico interaction of one chalcone with a putative caffeic acid 3-O-methyltransferase from Meloidogyne incognita.
PubMed:
Enhancement of 4-acetylantroquinonol B production by supplementation of its precursor during submerged fermentation of Antrodia cinnamomea.
PubMed:
The synthesis of the pyranonaphthoquinones dehydroherbarin and anhydrofusarubin using Wacker oxidation methodology as a key step and other unexpected oxidation reactions with ceric ammonium nitrate and salcomine.
PubMed:
2,4,5-TMBA, a natural inhibitor of cyclooxygenase-2, suppresses adipogenesis and promotes lipolysis in 3T3-L1 adipocytes.
PubMed:
Synthesis and antioxidant, cytotoxicity and antimicrobial activities of novel curcumin mimics.
PubMed:
A concise synthesis of the naphthalene portion of purpuromycin.
PubMed:
Production of a COX-2 inhibitor, 2,4,5-trimethoxybenzaldehyde, with submerged cultured Antrodia camphorata.
PubMed:
Synthesis of microfolicoumarin, a constituent of Cedrelopsis microfoliata.
PubMed:
Inhibition of cyclooxygenase (COX) enzymes by compounds from Daucus carota L. Seeds.
PubMed:
Structural and sensory characterization of compounds contributing to the bitter off-taste of carrots (Daucus carota L.) and carrot puree.
PubMed:
[Studies on the chemical constituents of Asarum longerhizomatosum C. F. Liang et C. S. Yang].
PubMed:
[Separation of two isomers in the products of condensation reaction with trimethoxybenzaldehyde as raw material and quick determination of the concentration of its intermediates by high performance liquid chromatography].
PubMed:
Pest-managing efficacy of trans-asarone isolated from Daucus carota L. seeds.
PubMed:
Cloning and expression of two novel hemin binding protein genes from Treponema denticola.
PubMed:
Phenylbutanoid dimers from the leaves of Alpinia flabellata.
PubMed:
Effect of Daucus carota var. boissieri extracts on immune response of Schistosoma mansoni infected mice.
PubMed:
IKP104-induced decay of tubulin: role of the A-ring binding site of colchicine.
PubMed:
The effectiveness of Salmonella strains TA100, TA102 and TA104 for detecting mutagenicity of some aldehydes and peroxides.
PubMed:
Isolation and characterization of a hemin-binding cell envelope protein from Porphyromonas gingivalis.
PubMed:
Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay: III. 72 coded chemicals.
PubMed:
Acridone Alkaloids and Other Constituents of the Leaves of Atalantia ceylanica.
PubMed:
The effects of colchicine analogues on the reaction of tubulin with iodo[14C]acetamide and N,N'-ethylenebis(iodoacetamide).
PubMed:
Tissue-specific and substrate-specific detection of aldehyde and pyridoxal oxidase in larval and imaginal tissues of Drosophila melanogaster.