1,2,4-trimethoxy-5-propenylbenzene

CAS: 494-40-6 C12 H16 O3 MW: 208.25712000

Identification

Nameasarone
IUPAC1,2,4-trimethoxy-5-prop-1-enylbenzene
CAS Number494-40-6
EINECS207-788-7
FDA UNIISearch
Molecular FormulaC12 H16 O3
Molecular Weight208.25712000
XlogP33.00 (est)

Regulatory

Physical Properties

Assay 92.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 62.00 to 63.00 °C. @ 760.00 mm Hg
Boiling Point 167.00 to 168.00 °C. @ 12.00 mm Hg, 265.00 to 267.00 °C. @ 760.00 mm Hg
Vapor Pressure 0.003000 mmHg @ 25.00 °C. (est)
Flash Point 226.00 °F. TCC ( 107.78 °C. )
logP (o/w) 3.406 (est)
Soluble in alcohol
Insoluble in water

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
IFRA Critical EffectCarcinogenicity
fragrance material specificationcis- and trans-Asarone as such should not be used as fragrance ingredients; essential oils containing cis- or trans-asarone (e.g. calamus oils) should not be used at a level such that the total concentration of cis- and trans-asarone exceeds 0.01% in consumer products.
IFRA RESTRICTION LIMITS IN THE FINISHED PRODUCT (%)Category 1: Products applied to the lips
NotesIFRA FLAVOR REQUIREMENTS:
Recommendation for asarone flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

asarum arifolium calamus root oil clove bud oil @ 1.08% Data clove leaf oil @ 0.45% Data clove stem oil india @ 0.50% Data

Synonyms

azaron benzene, 1,2,4-trimethoxy-5-(1-propen-1-yl)- benzene, 1,2,4-trimethoxy-5-(1-propenyl)- benzene, 1,2,4-trimethoxy-5-propenyl- 2,4,5- trimethoxy-1-propenylbenzene 1,2,5- trimethoxy-4-propenyl benzene 1,2,4- trimethoxy-5-(prop-1-en-1-yl)benzene 1,2,4- trimethoxy-5-prop-1-enylbenzene 1,2,4- trimethoxy-5-propenyl benzene 1,2,4- trimethoxy-5-propenylbenzene PubMed: Proteomic analysis of β-asarone induced cytotoxicity in human glioblastoma U251 cells. PubMed: α-Asarone attenuates microglia-mediated neuroinflammation by inhibiting NF kappa B activation and mitigates MPTP-induced behavioral deficits in a mouse model of Parkinson's disease. PubMed: β-asarone and levodopa co-administration protects against 6-hydroxydopamine-induced damage in parkinsonian rat mesencephalon by regulating autophagy: down-expression Beclin-1 and light chain 3B and up-expression P62. PubMed: β-asarone inhibits gastric cancer cell proliferation. PubMed: Effect of α-asarone on angiogenesis and matrix metalloproteinase. PubMed: [Pharmacokinetic study on dry powder inhalation administration of α-asarone in rats]. PubMed: β-Asarone Mitigates Amyloidosis and Downregulates RAGE in a Transgenic Mouse Model of Alzheimer's Disease. PubMed: Coadministration of β-asarone and levodopa increases dopamine in rat brain by accelerating transformation of levodopa: a different mechanism from Madopar. PubMed: Beta-asarone attenuates amyloid beta-induced autophagy via Akt/mTOR pathway in PC12 cells. PubMed: β-Asarone (cis-2,4,5-trimethoxy-1-allyl phenyl), attenuates pro-inflammatory mediators by inhibiting NF-κB signaling and the JNK pathway in LPS activated BV-2 microglia cells. PubMed: Distribution of α-asarone in brain following three different routes of administration in rats. PubMed: Neuroprotective Effects of β-Asarone Against 6-Hydroxy Dopamine-Induced Parkinsonism via JNK/Bcl-2/Beclin-1 Pathway. PubMed: β-Asarone prevents autophagy and synaptic loss by reducing ROCK expression in asenescence-accelerated prone 8 mice. PubMed: Reversing P-glycoprotein-mediated multidrug resistance in vitro by α-asarone and β-asarone, bioactive cis-trans isomers from Acorus tatarinowii. PubMed: β-asarone reverses chronic unpredictable mild stress-induced depression-like behavior and promotes hippocampal neurogenesis in rats. PubMed: The involvement of neuronal nitric oxide synthase in antiepileptic action of alpha-asarone on pentylenetetrazol molding rats. PubMed: α-Asarone Ameliorates Memory Deficit in Lipopolysaccharide-Treated Mice via Suppression of Pro-Inflammatory Cytokines and Microglial Activation. PubMed: Identification of both GABAA receptors and voltage-activated Na(+) channels as molecular targets of anticonvulsant α-asarone. PubMed: Beta-asarone, a major component of Acorus tatarinowii Schott, attenuates focal cerebral ischemia induced by middle cerebral artery occlusion in rats. PubMed: Alpha-Asarone Protects Endothelial Cells from Injury by Angiotensin II. PubMed: Development of intravenous lipid emulsion of α-asarone with significantly improved safety and enhanced efficacy. PubMed: Effect of Beta-Asarone on Impairment of Spatial Working Memory and Apoptosis in the Hippocampus of Rats Exposed to Chronic Corticosterone Administration. PubMed: β-Asarone induces senescence in colorectal cancer cells by inducing lamin B1 expression. PubMed: α-asarone from Acorus gramineus alleviates epilepsy by modulating A-type GABA receptors. PubMed: Purple perilla extracts with α-asarone enhance cholesterol efflux from oxidized LDL-exposed macrophages. PubMed: Antidepressant-like effects of essential oil and asarone, a major essential oil component from the rhizome of Acorus tatarinowii. PubMed: β-Asarone, an active principle of Acorus calamus rhizome, inhibits morphogenesis, biofilm formation and ergosterol biosynthesis in Candida albicans. PubMed: Anticonvulsant activity of acute and chronic treatment with a-asarone from Acorus gramineus in seizure models. PubMed: [Quality evaluation and stability investigation of asarone submicro emulsion injection]. PubMed: Systemic delivery of alpha-asarone with Kolliphor HS 15 improves its safety and therapeutic effect on asthma. PubMed: Hepatic Metabolism of Carcinogenic β-Asarone. PubMed: β-Asarone inhibits neuronal apoptosis via the CaMKII/CREB/Bcl-2 signaling pathway in an in vitro model and AβPP/PS1 mice. PubMed: β-asarone from Acorus gramineus alleviates depression by modulating MKP-1. PubMed: Assessment of the genotoxic activity of alpha-asarone and its derivatives in the comet assay. PubMed: Synthesis and antifeedant activity of novel alpha-asarone derivatives against stored-product pests. PubMed: Analysis of transformation and excretion of β-asarone in rabbits with GC-MS. PubMed: Loading amorphous Asarone in mesoporous silica SBA-15 through supercritical carbon dioxide technology to enhance dissolution and bioavailability. PubMed: Anxiolytic-like effect of α-asarone in mice. PubMed: Role of Acorus calamus and alpha-asarone on hippocampal dependent memory in noise stress exposed rats. PubMed: Cerebrovascular protection of β-asarone in Alzheimer's disease rats: a behavioral, cerebral blood flow, biochemical and genic study. PubMed: Alpha-Asarone, a Major Component of Acorus gramineus, Attenuates Corticosterone-Induced Anxiety-Like Behaviours via Modulating TrkB Signaling Process. PubMed: Synthesis and highly potent hypolipidemic activity of alpha-asarone- and fibrate-based 2-acyl and 2-alkyl phenols as HMG-CoA reductase inhibitors. PubMed: Beta-asarone attenuates ischemia-reperfusion-induced autophagy in rat brains via modulating JNK, p-JNK, Bcl-2 and Beclin 1. PubMed: Discrimination of fennel chemotypes applying IR and Raman spectroscopy: discovery of a new γ-asarone chemotype. PubMed: Nitro Derivatives of Naturally Occurring β -Asarone and Their Anticancer Activity. PubMed: Comparative study of the cytotoxicity and genotoxicity of alpha- and Beta-asarone. PubMed: Pharmacokinetics of beta-asarone in rabbit blood, hippocampus, cortex, brain stem, thalamus and cerebellum. PubMed: Fate of β-asarone in Ayurvedic Sodhana process of Vacha. PubMed: Synthesis, antifeedant activity against Coleoptera and 3D QSAR study of alpha-asarone derivatives. PubMed: Alpha- and beta-asarone in herbal medicinal products. A case study. PubMed: Cognitive enhancing effects of alpha asarone in amnesic mice by influencing cholinergic and antioxidant defense mechanisms. PubMed: β-Asarone protects PC12 cells against OGD/R-induced injury via attenuating Beclin-1-dependent autophagy. PubMed: Beta-asarone induces LoVo colon cancer cell apoptosis by up-regulation of caspases through a mitochondrial pathway in vitro and in vivo. PubMed: An efficient combination of supercritical fluid extraction and high-speed counter-current chromatography to extract and purify (E)- and (Z)-diastereomers of α-asarone and β-asarone from Acorus tatarinowii Schott. PubMed: Simultaneous determination of α-, β- and γ-asarone in Acorus tatarinowii by microemulsion electrokinetic chromatography with [BMIM]PF6 as oil phase. PubMed: Development and evaluation of α-asarone transdermal patches based on hot-melt pressure-sensitive adhesives. PubMed: A rapid HPLC-ESI-MS/MS method for determination of β-asarone, a potential anti-epileptic agent, in plasma after oral administration of Acorus calamus extract to rats. PubMed: Beta-asarone attenuates beta-amyloid-induced apoptosis through the inhibition of the activation of apoptosis signal-regulating kinase 1 in SH-SY5Y cells. PubMed: Radioprotection by α-asarone: prevention of genotoxicity and hematopoietic injury in mammalian organism. PubMed: Activities of α-asarone in various animal seizure models and in biochemical assays might be essentially accounted for by antioxidant properties. PubMed: Beta-asarone inhibits synaptic inputs to airway preganglionic parasympathetic motoneurons. PubMed: GC-MS method for determination and pharmacokinetic study of four phenylpropanoids in rat plasma after oral administration of the essential oil of Acorus tatarinowii Schott rhizomes. PubMed: Protective effects of components of the Chinese herb grassleaf sweetflag rhizome on PC12 cells incubated with amyloid-beta42. PubMed: Alpha-Asarone incorporated in mixed micelles suitable for intravenous administration: formulation, in-vivo distribution and anaphylaxis study. PubMed: Separation of cis- and trans-Asarone from Acorus tatarinowii by Preparative Gas Chromatography. PubMed: Beta-asarone protection against beta-amyloid-induced neurotoxicity in PC12 cells via JNK signaling and modulation of Bcl-2 family proteins. PubMed: Development of drug-in-adhesive transdermal patch for α-asarone and in vivo pharmacokinetics and efficacy evaluation. PubMed: Beta-asarone attenuates neuronal apoptosis induced by Beta amyloid in rat hippocampus. PubMed: Metabolism mediated interaction of α-asarone and Acorus calamus with CYP3A4 and CYP2D6. PubMed: Asarone inhibits adipogenesis and stimulates lipolysis in 3T3-L1 adipocytes. PubMed: Reduction of beta-asarone in acori rhizoma by decoction. PubMed: Bioanalytical investigation of asarone in connection with Acorus calamus oil intoxications. PubMed: Effects of alpha-asarone on the glutamate transporter EAAC1 in Xenopus oocytes. PubMed: Reinvestigation of structure-activity relationship of methoxylated chalcones as antimalarials: synthesis and evaluation of 2,4,5-trimethoxy substituted patterns as lead candidates derived from abundantly available natural β-asarone. PubMed: Beta-asarone improves cognitive function by suppressing neuronal apoptosis in the beta-amyloid hippocampus injection rats. PubMed: Design, synthesis, and docking of highly hypolipidemic agents: Schizosaccharomyces pombe as a new model for evaluating alpha-asarone-based HMG-CoA reductase inhibitors. PubMed: 2,4,5-trimethoxycinnamic acid: the major metabolite of alpha-asarone, retains most of the pharmacological properties of alpha-asarone. PubMed: Metabolite profiling of tissues of Acorus calamus and Acorus tatarinowii rhizomes by using LMD, UHPLC-QTOF MS, and GC-MS. PubMed: Neuroprotective effect of alpha-asarone on spatial memory and nitric oxide levels in rats injected with amyloid-beta((25-35)). PubMed: Hepatotoxic potential of asarones: in vitro evaluation of hepatotoxicity and quantitative determination in herbal products. PubMed: Larvicidal activity of the essential oil of Youngia japonica aerial parts and its constituents against Aedes albopictus. PubMed: [Effects of beta-asarone on expression of FOS and GAD65 in cortex of epileptic rat induced by penicillin]. PubMed: [Comparison of kinetic behavior in both plasma and tissue after intravenous administration of alpha-asarone in lipid emulsion and aqueous solution in rats and mice]. PubMed: [Effects of beta-asarone on morphology and cell viability in PC12 cells and cultured rat cortical neurons]. PubMed: Preparation and characterization of solid lipid nanoparticles loaded with alpha-Asarone. PubMed: Effect of alpha-asarone and a derivative on lipids, bile flow and Na+/K+-ATPase in ethinyl estradiol-induced cholestasis in the rat. PubMed: Rapid assessment of beta-asarone content of Acorus calamus by micellar electrokinetic capillary chromatography. PubMed: Alpha-asarone inhibits HMG-CoA reductase, lowers serum LDL-cholesterol levels and reduces biliary CSI in hypercholesterolemic rats. PubMed: Protection of cultured rat cortical neurons from excitotoxicity by asarone, a major essential oil component in the rhizomes of Acorus gramineus. PubMed: Antifungal activity of beta-asarone from rhizomes of Acorus gramineus. PubMed: [Effects of beta-asarone on expression of c-fos in kindling epilepsy rat brain]. PubMed: Antioxidant property of alpha-asarone against noise-stress-induced changes in different regions of rat brain. PubMed: [Pharmacology and toxicology of Guatteria gaumeri and alpha-asarone]. PubMed: A herbal medicine for Alzheimer's disease and its active constituents promote neural progenitor proliferation. PubMed: Systematic study of beta-asarone-rich volatile oil from Acori graminei rhizoma by off-line supercritical CO2 extraction-gas chromatography-mass spectrometry. PubMed: Identification of an EcoRI restriction site for a rapid and precise determination of beta-asarone-free Acorus calamus cytotypes. PubMed: [Pharmacokinetics of beta-asarone in rats]. PubMed: [Protective effects of beta-asarone on cultured rat cortical neurons damage induced by glutamate]. PubMed: Dominant lethal study of alpha-asarone in male mice. PubMed: alpha-Asarone toxicity in long-term cultures of adult rat hepatocytes. PubMed: Compositional variations and anthelmentic activity of essential oils from rhizomes of different wild populations of Acorus calamus L. and its major component, beta-Asarone. PubMed: Effects of asarone and beta-asarone on conditioned responses, fighting behaviour and convulsions. PubMed: Genotoxicity of alpha-asarone analogues. PubMed: Quantitative determination of beta-asarone in calamus by high-performance thin-layer chromatography. PubMed: [Asarone and its biological properties]. PubMed: Molecular and chemical profiling of 'sweet flag' (Acorus calamus L.) germplasm from India. PubMed: [1,2,4-TRIMETHOXY-5-PROPENYLBENZENE: A POSSIBLE SOURCE OF A FAMILY OF ANXIOLYTIC DRUGS]. PubMed: [Study on alpha-asarone reservoir-type patch]. PubMed: Comparison of GC-MS and TLC techniques for asarone isomers determination. PubMed: Mobility inhibition and nematocidal activity of asarone and related phenylpropanoids on second-stage larvae of Toxocara canis. PubMed: Disposition of asarone after intravenous administration to rabbits assessed using HPLC. PubMed: [The effective parts of liangxue tongyu prescription on cooling-blood and activating-blood and analysis of chemical constituents by HPLC-MS and GC-MS]. PubMed: Consumer and farmer safety evaluation of application of botanical pesticides in black pepper crop protection. PubMed: In vitro genotoxic evaluation of three alpha-asarone analogues. PubMed: Pest-managing efficacy of trans-asarone isolated from Daucus carota L. seeds. PubMed: A mild and convenient procedure for the conversion of toxic beta-asarone into rare phenylpropanoids: 2,4,5-trimethoxycinnamaldehyde and gamma-asarone. PubMed: Synthesis and hypolipidemic and antiplatelet activities of alpha-asarone isomers in humans (in vitro), mice (in vivo), and rats (in vivo). PubMed: Inhibition of lipid synthesis and secretion in long-term cultures of adult rat hepatocytes by alpha-asarone. PubMed: Molecular docking of the highly hypolipidemic agent alpha-asarone with the catalytic portion of HMG-CoA reductase. PubMed: New studies on trans-anethole oxide and trans-asarone oxide. PubMed: Gas-liquid chromatographic determination of beta-asarone in wines and flavors. PubMed: Dominant lethal study of alpha-asarone in male and female mice after sub-chronic treatment. PubMed: Synthesis and hypolipidaemic evaluation of a series of alpha-asarone analogues related to clofibrate in mice. PubMed: alpha-asarone congeners as hypolipidemic agents. Pseudoreceptor versus minireceptor modeling. PubMed: Genotoxicity of the alkenylbenzenes alpha- and beta-asarone, myristicin and elimicin as determined by the UDS assay in cultured rat hepatocytes. PubMed: An overview on traditional uses and pharmacological profile of Acorus calamus Linn. (Sweet flag) and other Acorus species. PubMed: Identification of insecticidal constituents of the essential oil of Acorus calamus rhizomes against Liposcelis bostrychophila Badonnel. PubMed: The Rhizomes of Acorus gramineus and the Constituents Inhibit Allergic Response In vitro and In vivo. PubMed: A fraction of Acorus calamus L. extract devoid of beta-asarone enhances adipocyte differentiation in 3T3-L1 cells. PubMed: Development of self-microemulsifying drug delivery systems for oral bioavailability enhancement of alpha-Asarone in beagle dogs. PubMed: Ultrasound-assisted conversion of toxic beta-asarone into nontoxic bioactive phenylpropanoid: isoacoramone, a metabolite of Piper marginatum and Acorus tararinowii. PubMed: One step conversion of toxic beta-asarone from Acorus calamus into 1-(2,4,5-trimethoxyphenyl)-1,2-dihydroxypropane and asaronaldehyde occurring in Piper clusii. PubMed: Sister-chromatid exchange induction produced by in vivo and in vitro exposure to alpha-asarone. PubMed: [A review of recent ten-year study on alpha-asarone]. PubMed: Hypolipidaemic and antiplatelet activity of phenoxyacetic acid derivatives related to alpha-asarone. PubMed: Synthesis and hypolipidemic activity of modified side chain alpha-asarone homologues. PubMed: [Teratogenic action of alpha-asarone in the mouse]. PubMed: Quantitative analysis of alpha, beta-thujone, pulegone, safrole, coumarin and beta-asarone in alcoholic beverages by selected-ion monitoring. PubMed: Simultaneous Determination of Volatile Constituents from Acorus tatarinowii Schott in Rat Plasma by Gas Chromatography-Mass Spectrometry with Selective Ion Monitoring and Application in Pharmacokinetic Study. PubMed: The efficacy of essential oils as natural preservatives in vegetable oil. PubMed: Bicycloillicinone asarone acetal: a novel prenylated C6-C3 compound increasing choline acetyltransferase (ChAT) activity from Illicium tashiroi. PubMed: Hypolipidaemic activity of alpha-asarone in mice. PubMed: The anticoagulant effect of beta-asarone in the mouse and the rat. PubMed: Mutagenicity testing of beta-asarone and commercial calamus drugs with Salmonella typhimurium. PubMed: [Teratogenic evaluation of alpha-asarone in the rat]. PubMed: Determination of beta-asarone, safrole, isosafrole and anethole in alcoholic drinks by high-performance liquid chromatography. PubMed: [Research on the anticarcinogenic activation of Acorus calcamus. Anticarcinogenic activation of alpha-asarone on human carcinoma cells]. PubMed: Status epilepticus treated by alpha-asarone. Report of 18 cases. PubMed: Studies on Acorus calamus. VI. Pharmacological actions of asarone and beta-asarone on cardiovascular system and smooth muscles. PubMed: Pharmacodynamical effects of asarone and beta-asarone. PubMed: Chemical compositions, phytotoxicity, and biological activities of Acorus calamus essential oils from Nepal. PubMed: [Composition of the essential oil from beta-Asarone free calamus.]. PubMed: Gas-liquid chromatographic determination of beta-asarone in wine: collaborative study. PubMed: Studies on Acorus calamus. V. Pharmacological actions of asarone and beta-asarone on central nervous system. PubMed: Spectrofluorometric determination of beta-asarone in sweet and dry vermouths. PubMed: [Thin-layer cromatographic and densitometric evaluation of beta-asarone in alcoholic flavored beverages (author's transl)]. PubMed: New compounds: structural analogs related to asarone and mescaline. PubMed: Is asarone a tranquilliser? PubMed: Is asarone a tranquilliser? PubMed: The mechanism of the tranquillizing action of asarone from Acorus calamus Linn. PubMed: Effect of asarone on experimentally induced conflict neurosis in rats. PubMed: ACTIONS OF ASARONE ON BEHAVIOR, STRESS, AND HYPERPYREXIA, AND ITS INTERACTION WITH CENTRAL STIMULANTS. PubMed: Spasmolytic activity of asarone and essential oil of Acorus calamus, Linn. PubMed: Interaction of asarone with mescaline, amphetamine and tremorine. PubMed: [ANALYSIS OF THE COMPONENTS OF ASARUM EUROPEUM L. VI. DETERMINATION OF THE VOLATILE OIL AND ASARONE-(1-PROPENYL-2,4,5,-TRIMETHOXY-BENZOL) CONTENT]. PubMed: [Chemical constituents from rhizomes of Acorus tatarinowii]. PubMed: Metabolism by grasshoppers of volatile chemical constituents from Mangifera indica and Solanum paniculatum leaves. PubMed: The effects of Acorus tatarinowii Schott on 5-HT concentrations, TPH2 and 5-HT1B expression in the dorsal raphe of exercised rats. PubMed: Terpenoid composition and antifungal activity of three commercially important essential oils against Aspergillus flavus and Aspergillus niger. PubMed: Antioxidant and α -amylase inhibitory property of phyllanthus virgatus L.: an in vitro and molecular interaction study. PubMed: Growth-Inhibiting and morphostructural effects of constituents identified in Asarum heterotropoides root on human intestinal bacteria. PubMed: Chemical composition and insecticidal activities of essential oils against diamondback moth, Plutella xylostella (L.) (Lepidoptera: Yponomeutidae). PubMed: Hypocholesterolemic and choleretic effects of three dimethoxycinnamic acids in relation to 2,4,5-trimethoxycinnamic acid in rats fed with a high-cholesterol/cholate diet. PubMed: Śodhana: An Ayurvedic process for detoxification and modification of therapeutic activities of poisonous medicinal plants. PubMed: Identification of sesquiterpene lactones in the Bryophyta (mosses) Takakia: Takakia species are closely related chemically to the Marchantiophyta (liverworts). PubMed: [Chemical Constituents from Cynanchum paniculatum]. PubMed: Development and validation of a high-performance liquid chromatographic method for the simultaneous quantification of marker constituents in Cheonwangbosimdan. PubMed: Chemical composition of the essential oil of aerial parts of Haussknechtia elymaitica Boiss. from Iran: a good natural source for trans-asaron. PubMed: Fumigant toxicity of Oriental sweetgum (Liquidambar orientalis) and valerian (Valeriana wallichii) essential oils and their components, including their acetylcholinesterase inhibitory activity, against Japanese termites (Reticulitermes speratus). PubMed: Spasmolytische wirkung des isoasaronfreien kalmus1. PubMed: [To the classification of commercial Calamus drugs]. PubMed: [Study on relationship of properties and drug release rate of hot melt pressure sensitive adhesive]. PubMed: The effects of Zibu Piyin Recipe components on scopolamine-induced learning and memory impairment in the mouse. PubMed: Phenolic constituents of Acorus gramineus. PubMed: In vitro acetylcholinesterase inhibitory activity of the essential oil from Acorus calamus and its main constituents. PubMed: Rhizoma acori graminei and its active principles protect PC-12 cells from the toxic effect of amyloid-beta peptide. PubMed: Comparison of the volatile oil composition of three Atalantia species. PubMed: Synthesis, anticancer and antioxidant activities of 2,4,5-trimethoxy chalcones and analogues from asaronaldehyde: structure-activity relationship. PubMed: [Research on liposoluble ingredients of Quchiling]. PubMed: Development of gas chromatography/mass spectrometry following headspace solid-phase microextraction for fast determination of asarones in plasma. PubMed: Gas chromatography-mass spectrometry analysis on compounds in volatile oils extracted from yuan zhi (radix polygalae) and shi chang pu (acorus tatarinowii) by supercritical CO2. PubMed: Asarones fromAcorus calamus L. Oil : Their effect on feeding behavior and dietary utilization inPeridroma saucia. PubMed: Enhanced toxicity of binary mixtures of larvicidal constituents from Asarum heterotropoides root to Culex pipiens pallens (Diptera: Culicidae). PubMed: Chemical composition, antinociceptive and anti-inflammatory properties of essential oil from the roots of Illicium lanceolatum. PubMed: Supercritical fluid CO₂ extraction of Acorus calamus L. (Arales: Araceae) and its contact toxicity to Sitophilus zeamais Motschusky (Coleoptera: Curculionidae). PubMed: Chemical compositions and anti-influenza activities of essential oils from Mosla dianthera. PubMed: Neuroprotective effect of honokiol and magnolol, compounds from Magnolia officinalis, on beta-amyloid-induced toxicity in PC12 cells. PubMed: Larvicidal activity of Asarum heterotropoides root constituents against insecticide-susceptible and -resistant Culex pipiens pallens and Aedes aegypti and Ochlerotatus togoi. PubMed: [Studies on chemical constituents of green algae Ulva pertusa]. PubMed: [Study on GC-MS fingerprint analysis in rhizome of volatile oil of Acorus tatarinowii]. PubMed: Chemical composition and biological activity of the volatile extracts of Achillea millefolium. PubMed: Discovery of gemfibrozil analogues that activate PPARα and enhance the expression of gene CPT1A involved in fatty acids catabolism. PubMed: Brazilian red propolis: unreported substances, antioxidant and antimicrobial activities. PubMed: A solid-phase microextraction GC/MS/MS method for rapid quantitative analysis of food and beverages for the presence of legally restricted biologically active flavorings. PubMed: Insecticidal effect and chemical composition of the volatile oil from Bergenia ligulata. PubMed: Positive GABA(A) receptor modulators from Acorus calamus and structural analysis of (+)-dioxosarcoguaiacol by 1D and 2D NMR and molecular modeling. PubMed: Supplemental ultraviolet-B induced changes in essential oil composition and total phenolics of Acorus calamus L. (sweet flag). PubMed: Quality assessment of a formulated Chinese herbal decoction, Kaixinsan, by using rapid resolution liquid chromatography coupled with mass spectrometry: A chemical evaluation of different historical formulae. PubMed: Structure-activity studies of the hepatocarcinogenicities of alkenylbenzene derivatives related to estragole and safrole on administration to preweanling male C57BL/6J x C3H/HeJ F1 mice. PubMed: Identification of host plant attractants for the carrot fly,Psila rosae. PubMed: Standardization and in vivo antioxidant activity of ethanol extracts of fruit and leaf of Piper sarmentosum. PubMed: [GC-MS analysis of essential oil from nutmeg processed by different traditional methods]. PubMed: [Effects of annao tablet on S100B and NPY of cortex in chronic epilepsy rats]. PubMed: 3D QSAR study of hypolipidemic asarones by comparative molecular surface analysis. PubMed: [Studies on the chemical constituents of Asarum longerhizomatosum C. F. Liang et C. S. Yang]. PubMed: Insecticidal activity against Aedes aegypti larvae of some medicinal South American plants. PubMed: [Study on the chemical constituents of Humulus scandens]. PubMed: [Chemical constituents from petroleum ether fraction of ethanol extract of Acorus tatarinowii]. PubMed: Larvicidal and structure-activity studies of natural phenylpropanoids and their semisynthetic derivatives against the tobacco armyworm Spodoptera litura (Fab.) (Lepidoptera: Noctuidae). PubMed: Inhibitors of HMG-CoA Reductase: Current and Future Prospects. PubMed: Fumigant antifungal activity of essential oil components from Acorus gramineus against three phytopathogenic fungi. PubMed: Volatiles from leaves and rhizomes of Fragrant Acorus spp. (Acoraceae). PubMed: Evaluation of analgesic and anti-inflammatory activities of Nectandra megapotamica (Lauraceae) in mice and rats. PubMed: Rapid determination of volatile constituents in safflower by microwave distillation and simultaneous solid-phase microextraction coupled with gas chromatography-mass spectrometry. PubMed: Rapid determination of essential oil in Acorus tatarinowii Schott. by pressurized hot water extraction followed by solid-phase microextraction and gas chromatography-mass spectrometry. PubMed: Micronucleus formation in human lymphocytes and in the metabolically competent human hepatoma cell line Hep-G2: results with 15 naturally occurring substances. PubMed: DNA profiling of Acorus calamus chemotypes differing in essential oil composition. PubMed: Central inhibitory effects of water extract of Acori graminei rhizoma in mice. PubMed: Structure-genotoxicity relationships of allylbenzenes and propenylbenzenes: a quantum chemical study. PubMed: Potential allelochemicals fromPistia stratiotes L. PubMed: Bioanalytical and clinical evaluation of 103 suspected cases of intoxications with psychoactive plant materials. PubMed: Chemical composition, oviposition deterrent and larvicidal activities against Aedes aegypti of essential oils from Piper marginatum Jacq. (Piperaceae). PubMed: A high performance liquid chromatography method for simultaneous determination of rosiglitazone and gemfibrozil in human plasma. PubMed: Variability in essential-oil composition of Piper marginatum sensu lato. PubMed: Suppression of MeIQ-induced SOS response by allylbenzenes from Asiasarum heterotropoides in the Salmonella typhimurium OY1001/1A2 umu test. PubMed: Fungicidal property of active component derived from Acorus gramineus rhizome against phytopathogenic fungi. PubMed: A simple and practical phase-separation approach to the recycling of a homogeneous metathesis catalyst. PubMed: Antioxidative activity of volatile extracts isolated from Angelica tenuissimae roots, peppermint leaves, pine needles, and sweet flag leaves. PubMed: A new amide from Asarum forbesii Maxim. PubMed: [Effects of beta-asaron on gene expression in mouse brain]. PubMed: Inhibition of cyclooxygenase (COX) enzymes by compounds from Daucus carota L. Seeds. PubMed: Antifungal and larvicidal compounds from the root bark of Cordia alliodora. PubMed: Getting to the root (Acorus calamus) of the problem. PubMed: Studies on anti-allergic components in the roots of Asiasarum sieboldi. PubMed: Central nervous system studies on an ethanol extract of Acorus calamus rhizomes. PubMed: [Antianaphylactic components of Asarum forbsii Maxin]. PubMed: [Chromosome-damaging effect of beta-asaron on human lymphocytes]. PubMed: [Spasmolytic actions of active principles of volatile oil of Acorus gramineus]. PubMed: [Extraction of thermolabile compounds with supercritical gases.]. PubMed: Nematicidal activity of plant essential oils and components from coriander (Coriandrum sativum), Oriental sweetgum (Liquidambar orientalis), and valerian (Valeriana wallichii) essential oils against pine wood nematode (Bursaphelenchus xylophilus). PubMed: Chemical composition of the essential oil and supercritical CO2 extract of Commiphora myrrha (Nees) Engl. and of Acorus calamus L. PubMed: Essential oils from two endemic species of Apiaceae from Iran. PubMed: [New data on composition of esssential oil from inflorescence of everlasting (Helichrysum arenarium(L.) Moench.)]. PubMed: SOS induction of selected naturally occurring substances in Escherichia coli (SOS chromotest). PubMed: [Variations of the essential oils in Acorua calamus L. and their major compositions]. PubMed: [Spasmolytic effect of isoasaron free calamus]. PubMed: [In vitro study of the expectorant effect of phenylpropane derivatives of hazelwort. 12. Active substances form Asarum europaeum. L]. PubMed: [Use of the mass spectrometer as a specific detector in the analysis of alcoholic beverages by gas-liquid chromatography].