7-acetoxy-4-methyl coumarin
beta-methylumbelliferyl acetate
Identification
| Name | 7-acetoxy-4-methyl coumarin |
| IUPAC | (4-methyl-2-oxochromen-7-yl) acetate |
| CAS Number | 2747-05-9 |
| EINECS | 220-386-6 |
| FDA UNII | Search |
| Molecular Formula | C12 H10 O4 |
| Molecular Weight | 218.20850000 |
| Nikkaji Number | J45.307B |
| XlogP3 | 2.00 (est) |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 355.3 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for 7-acetoxy-4-methyl coumarin usage levels up to | not for fragrance use. |
| Recommendation for 7-acetoxy-4-methyl coumarin flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
7-
acetoxy-4-methylcoumarin
7-(
acetyloxy)-4-methyl-2-benzopyrone
2H-1-
benzopyran-2-one, 7-(acetyloxy)-4-methyl-
(4-
methyl-2-oxochromen-7-yl) acetate
4-
methylumbelliferyl acetate
beta-
methylumbelliferyl acetate
PubMed:
Downregulation of Rubisco Activity by Non-enzymatic Acetylation of RbcL.
PubMed:
Comparative specificities of Calreticulin Transacetylase to O-acetyl, N-acetyl and S-acetyl derivative of 4-methylcoumarins and their inhibitory effect on AFB1-induced genotoxicity in vitro and in vivo.
PubMed:
Novel thiocoumarins as inhibitors of TNF-alpha induced ICAM-1 expression on human umbilical vein endothelial cells (HUVECs) and microsomal lipid peroxidation.
PubMed:
Mechanism of biochemical action of substituted benzopyran-2-ones. Part 8: Acetoxycoumarin: protein transacetylase specificity for aromatic nuclear acetoxy groups in proximity to the oxygen heteroatom.
PubMed:
Chemoprevention of benzene-induced bone marrow and pulmonary genotoxicity.
PubMed:
Can superoxide organic chemistry be observed within the liposomal bilayer?
PubMed:
Interaction of tetrahydroaminoacridine with acetylcholinesterase and butyrylcholinesterase.
PubMed:
Ligand exclusion on acetylcholinesterase.