aflatoxin B2, crystalline

(6aR,9aS)-4-methoxy-2,3,6a,8,9,9a-hexahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene-1,11-dione

CAS: 7220-81-7 C17 H14 O6 MW: 314.29378000

Identification

Nameaflatoxin B2, crystalline
CAS Number7220-81-7
EINECS230-618-8
FDA UNII7SKR7S646P
Molecular FormulaC17 H14 O6
Molecular Weight314.29378000
MDL NumberMFCD00078140
Nikkaji NumberJ37.504G
Beilstein1355115

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 287.50 °C. @ 760.00 mm Hg
Boiling Point 521.00 °C. @ 760.00 mm Hg (est)
Flash Point 453.00 °F. TCC ( 234.00 °C. ) (est)
logP (o/w) 1.802 (est)
Soluble in water, 585.4 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityoral-duck LD50 1700 ug/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryinformation only not used for fragrances or flavors
Recommendation for aflatoxin B2, crystalline usage levels up tonot for fragrance use.
Recommendation for aflatoxin B2, crystalline flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

found in nature

Synonyms

cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione, 2,3,6a,8,9,9a-hexahydro-4-methoxy-, (6aR,9aS)- (6aR,9aS)-4- methoxy-2,3,6a,8,9,9a-hexahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene-1,11-dione (9aS,6aR)-4- methoxy-2,3,6a,9a-tetrahydro-8H,9H-cyclopenta[1,2-c]oxolano[3',2'-5,4]furano[2,3-h]chromene-1,11-dione PubMed: Aflatoxin Toxicity PubMed: Detection of Aflatoxins in Different Matrices and Food-Chain Positions PubMed: Polyphasic Assessment of Aflatoxin Production Potential in Selected Aspergilli PubMed: Assessing Aflatoxin Exposure Risk from Peanuts and Peanut Products Imported to Taiwan PubMed: Limited survey on aflatoxin contamination in rice PubMed: Magnetic nanogold microspheres-based lateral-flow immunodipstick for rapid detection of aflatoxin B2 in food PubMed: Incidence of aflatoxin contamination in non-perishable food commodities PubMed: Aflatoxin (B1 , B2 , G1 , and G2 ) contamination in rice of Mexico and Spain, from local sources or imported PubMed: Aflatoxins and ochratoxin A in maize of Punjab, Pakistan PubMed: Simultaneous determination of aflatoxin B?, B?, G?, and G? in corn powder, edible oil, peanut butter, and soy sauce by liquid chromatography with tandem mass spectrometry utilizing turbulent flow chroma PubMed: Mycotoxin Dietary Exposure Assessment through Fruit Juices Consumption in Children and Adult Population PubMed: [Aflatoxins--health risk factors] PubMed: Use of isotope-labeled aflatoxins for LC-MS/MS stable isotope dilution analysis of foods PubMed: Elimination of Aflatoxins B1 and B2 in White and Red Wines by Bentonite Fining. Efficiency and Impact on Wine Quality PubMed: Risk Assessment and Mitigation of the Mycotoxin Content in Medicinal Plants by the Infusion Process PubMed: Comprehensive comparison of multiple quantitative near-infrared spectroscopy models for Aspergillus flavus contamination detection in peanut PubMed: Novel Aflatoxin-Degrading Enzyme from Bacillus shackletonii L7 PubMed: Determination of mycotoxin exposure in Germany using an LC-MS/MS multibiomarker approach PubMed: Mass spectrometric identification and toxicity assessment of degraded products of aflatoxin B1 and B2 by Corymbia citriodora aqueous extracts PubMed: An aptamer affinity column for purification and enrichment of aflatoxin B(1) and aflatoxin B(2) in agro-products PubMed: Survey of aflatoxins in beer sold in Canada PubMed: Aflatoxin Detoxification in Rice using Citric Acid PubMed: Bottled water: analysis of mycotoxins by LC-MS/MS PubMed: [Aflatoxin contamination level in artisanal and industrial peanut butter food in Dakar (Senegal)] PubMed: Influence of dietary patterns on contaminants bioaccessibility and intestinal transport by in vitro assays PubMed: Effects of feeding corn naturally contaminated with aflatoxin B1 and B2 on hepatic functions of broilers PubMed: A direct determination of AFBs in vinegar by aptamer-based surface plasmon resonance biosensor PubMed: Reduced graphene oxide-zinc oxide nanocomposite as dispersive solid-phase extraction sorbent for simultaneous enrichment and purification of multiple mycotoxins in Coptidis rhizoma (Huanglian) and analy PubMed: Reduced Graphene Oxide-Gold Nanoparticle Nanoframework as a Highly Selective Separation Material for Aflatoxins PubMed: Effect on public health of a possible increase of the maximum level for 'aflatoxin total' from 4 to 10ÿ?g/kg in peanuts and processed products thereof, intended for direct human consumption or use as an PubMed: Occurrence of mycotoxins in feed as analyzed by a multi-mycotoxin LC-MS/MS method PubMed: Incidence of aflatoxins in Iran pistachio nuts PubMed: Aflatoxins and heavy metals in animal feed in Iran PubMed: Serum aflatoxin levels of the healthy adult population living in the north and south regions of Turkey PubMed: Aflatoxin destruction by microwave heating PubMed: An evaluation of aflatoxin and cyclopiazonic acid production in Aspergillus oryzae PubMed: [Determination of mycotoxins in pu-erh tea, black tea, and green tea samples] PubMed: Aspergillus section Flavi and aflatoxins in dried figs and nuts in Algeria PubMed: Aflatoxin levels and exposure assessment of Spanish infant cereals PubMed: Optimization and validation of a HPLC method for simultaneous determination of aflatoxin B1, B2, G1, G2, ochratoxin A and zearalenone using an experimental design PubMed: Aflatoxin levels in chronic hepatitis B patients with cirrhosis or hepatocellular carcinoma in Bal?kesir, Turkey PubMed: Multiple Mycotoxins in Rice: Occurrence and Health Risk Assessment in Children and Adults of Punjab, Pakistan PubMed: Effect of Drying Temperatures and Exposure Times on Aspergillus flavus Growth and Aflatoxin Production on Artificially Inoculated Hazelnuts PubMed: Determination and chemometric evaluation of total aflatoxin, aflatoxin B1, ochratoxin A and heavy metals content in corn flours from Turkey PubMed: Aflatoxins in pozol, a nixtamalized, maize-based food PubMed: Simultaneous Determination of Multi-Mycotoxins in Cereal Grains Collected from South Korea by LC/MS/MS PubMed: Mycotoxin contamination of animal feedingstuff: detoxification by gamma-irradiation and reduction of aflatoxins and ochratoxin A concentrations PubMed: Occurrence of aflatoxins in export-quality Pakistani rice PubMed: Occurrence of aflatoxins B1, B2, G1 and G2 in cooked food components of whole meals marketed in fast food outlets of the city of S?o Paulo, SP, Brazil PubMed: Determination of aflatoxins in imported rice to Iran PubMed: Rapid analysis of aflatoxins B1, B2, and ochratoxin A in rice samples using dispersive liquid-liquid microextraction combined with HPLC PubMed: Production of aflatoxin B(1) and B(2) by Aspergillus flavus in inoculated wheat using typical craft beer malting conditions PubMed: Liquid chromatography - high resolution mass spectrometry method for monitoring of 17 mycotoxins in human plasma for exposure studies PubMed: Determination of mycotoxins in feedstuffs and ruminant's milk using an easy and simple LC-MS/MS multiresidue method PubMed: Optimized QuEChERS Method Combined with UHPLC-MS/MS for the Simultaneous Determination of 15 Mycotoxins in Liquorice PubMed: Distribution of aflatoxins in product and by-products during glucose production from contaminated corn PubMed: A rapid enzymatic method for aflatoxin B detection PubMed: A simple sample pretreatment method for multi-mycotoxin determination in eggs by liquid chromatography tandem mass spectrometry PubMed: Natural co-occurrence of ochratoxin A, ochratoxin B and aflatoxins in Sicilian red wines PubMed: Evaluation of citrus flavonoids against Aspergillus parasiticus in maize: Aflatoxins reduction and ultrastructure alterations PubMed: Reduction of aflatoxins (B?, B?, G?, and G?) in soybean-based model systems PubMed: Anti-idiotypic nanobody-phage display-mediated real-time immuno-PCR for sensitive, simultaneous and quantitative detection of total aflatoxins and zearalenone in grains PubMed: Simultaneous determination of six mycotoxins in peanut by high-performance liquid chromatography with a fluorescence detector PubMed: A facile one-pot green synthesis of ?-cyclodextrin decorated porous graphene nanohybrid as a highly efficient adsorbent for extracting aflatoxins from maize and animal feeds PubMed: Fungal Biodeterioration, Aflatoxin Contamination, and Nutrient Value of "Suya Spices" PubMed: [Survey of aflatoxins contamination of foodstuffs and edible oil in Shenzhen] PubMed: The preparation, validation and certification of the aflatoxin content of two peanut butter reference materials PubMed: Survey of breakfast and infant cereals for aflatoxins B1, B2, G1 and G2 PubMed: 2,3-Dideoxyglucosides of selected terpene phenols and alcohols as potent antifungal compounds PubMed: Molecular characterization of mycobiota and aflatoxin contamination of retail wheat flours from Jeddah markets PubMed: Occurrence of aflatoxins B1, B2, G1 and G2 in some Brazilian pet foods PubMed: Simultaneous Analysis of 20 Mycotoxins in Grapes and Wines from Hexi Corridor Region (China): Based on a QuEChERS?UHPLC?MS/MS Method PubMed: [Using HTS-ELISA method to make anti-aflatoxin M1 monoclonal antibody] PubMed: A reliable liquid chromatography-tandem mass spectrometry method for simultaneous determination of multiple mycotoxins in fresh fish and dried seafoods PubMed: Aflatoxin in raw walnut kernels marketed in Tehran, Iran PubMed: Aspergillus and aflatoxin in groundnut (Arachis hypogaea L.) and groundnut cake in Eastern Ethiopia PubMed: Banana peel: an effective biosorbent for aflatoxins PubMed: Aflatoxins in sunflower seeds and unrefined sunflower oils from Singida, Tanzania PubMed: Degradation kinetics of aflatoxin B(1) and B(2) in solid medium by using pulsed light irradiation PubMed: Detection of Aflatoxigenic and Atoxigenic Mexican Aspergillus Strains by the Dichlorvos?Ammonia (DV?AM) Method PubMed: Effect of UV irradiation on aflatoxin reduction: a cytotoxicity evaluation study using human hepatoma cell line PubMed: Utilization of agro-wastes to inhibit aflatoxins synthesis by Aspergillus parasiticus: A biotreatment of three cereals for safe long-term storage PubMed: Tissue deposition and clearance of aflatoxins from broiler chickens fed a contaminated diet PubMed: Occurrence of mycotoxins in refrigerated pizza dough and risk assessment of exposure for the Spanish population PubMed: Effect of dietary acids on the formation of aflatoxin B2a as a means to detoxify aflatoxin B1 PubMed: Molecular docking studies and in vitro degradation of four aflatoxins (AFB(1) , AFB(2) , AFG(1) , and AFG(2) ) by a recombinant laccase from Saccharomyces cerevisiae PubMed: [Biological contamination by micromycetes in dried Boletus edulis: research of aflatoxin B1, B2 G1, G2 and ochratoxin A] PubMed: Evaluation of atoxigenic isolates of Aspergillus flavus as potential biocontrol agents for aflatoxin in maize PubMed: Occurrence of aflatoxins B1, B2, G1, and G2 in peanuts and their products marketed in the region of Campinas, Brazil in 1995 and 1996 PubMed: Aflatoxins in ginseng roots PubMed: [Determination of aflatoxins in nelumbinis semen by immunoaffinity column clean-up and HPLC-FLD with on-line post-column photochemical derivatization and LC-MS/MS confirmation] PubMed: Aflatoxin residues in eggs of laying Japanese quail after long-term administration of rations containing low levels of aflatoxin B1 PubMed: Validation of the procedure for the simultaneous determination of aflatoxins ochratoxin A and zearalenone in cereals using HPLC-FLD PubMed: Substrate suitability of different genotypes of sorghum in relation to Aspergillus infection and aflatoxin production PubMed: Determination of 16 mycotoxins in vegetable oils using a QuEChERS method combined with high-performance liquid chromatography-tandem mass spectrometry PubMed: Development and validation of a high-performance liquid chromatography method with post-column derivatization for the detection of aflatoxins in cereals and grains PubMed: Simultaneous determination of aflatoxins B2 and G2 in peanuts using spectrofluorescence coupled with parallel factor analysis PubMed: The effect of mycotoxins found in some herbal plants on biochemical parameters in blood of female albino mice PubMed: Prevalence and probabilistic health risk assessment of aflatoxins B(1), B(2), G(1), and G(2) in Iranian edible oils PubMed: Molasses supplementation promotes conidiation but suppresses aflatoxin production by small sclerotial Aspergillus flavus PubMed: Toxigenic potentiality of Aspergillus flavus and Aspergillus parasiticus strains isolated from black pepper assessed by an LC-MS/MS based multi-mycotoxin method PubMed: Aflatoxins and ochratoxin A and their Aspergillus causal species in Tunisian cereals PubMed: Survey of fungal counts and natural occurrence of aflatoxins in Malaysian starch-based foods PubMed: Development of a liquid chromatography/time-of-flight mass spectrometric method for the simultaneous determination of trichothecenes, zearalenone and aflatoxins in foodstuffs PubMed: A survey of aflatoxin in cotton seed in Iran by HPLC with on-line photochemical derivatisation and fluorescence detection PubMed: Development of immunochromatography strip-test using nanocolloidal gold-antibody probe for the rapid detection of aflatoxin B1 in grain and feed samples PubMed: Mycotoxins and mycotoxigenic moulds in nuts and sunflower seeds for human consumption PubMed: An oligosorbent-based aptamer affinity column for selective extraction of aflatoxin B(2) prior to HPLC with fluorometric detection PubMed: Comparison of three methods for determining aflatoxins in melon seeds PubMed: Advantages and drawbacks of immunoaffinity columns in analysis of mycotoxins in food PubMed: Solvent-efficient thin-layer chromatographic method for the determination of aflatoxins B1, B2, G1, and G2 in corn and peanut products: collaborative study PubMed: Lipid metabolism of commercial layers fed diets containing aflatoxin, fumonisin, and a binder PubMed: Development of a liquid chromatography/tandem mass spectrometry method for the simultaneous determination of 16 mycotoxins on cellulose filters and in fungal cultures PubMed: Biosorption of B-aflatoxins Using Biomasses Obtained from Formosa Firethorn [Pyracantha koidzumii (Hayata) Rehder] PubMed: Broiler aflatoxicosis with recovery after replacement of the contaminated diet PubMed: Antifungal properties and inhibitory effects upon aflatoxin production of Thymus vulgaris L. by Aspergillus flavus Link PubMed: Simultaneous determination of aflatoxins B?, B?, G?, and G? in foods and feed materials PubMed: Co-occurrence of aflatoxins B1, B2, G1, G2, zearalenone and fumonisin B1 in Brazilian corn PubMed: Rapid determination of total aflatoxins and ochratoxins A in meat products by immuno-affinity fluorimetry PubMed: Graphene-coated magnetic-sheet solid-phase extraction followed by high-performance liquid chromatography with fluorescence detection for the determination of aflatoxins B(1) , B(2) , G(1) , and G(2) in PubMed: Liquid chromatographic method for determination of aflatoxins B1, B2, G1, and G2 in corn and peanut products: collaborative study PubMed: Retention and distribution of aflatoxin in tissues of chicks fed aflatoxin-contaminated poultry rations amended with soil PubMed: Pathological changes in the immune organs of broiler chickens fed on corn naturally contaminated with aflatoxins B1 and B2 PubMed: Modulation of macrophage activity by aflatoxins B1 and B2 and their metabolites aflatoxins M1 and M2 PubMed: Assessment of azole fungicides as a tool to control growth of Aspergillus flavus and aflatoxin B(1) and B(2) production in maize PubMed: Co-occurrence of aflatoxins B?, B?, G? and G?, ochratoxin A, zearalenone, deoxynivalenol, and citreoviridin in rice in Brazil PubMed: Development of Multiple Heart-Cutting Two-Dimensional Liquid Chromatography Coupled to Quadrupole-Orbitrap High Resolution Mass Spectrometry for Simultaneous Determination of Aflatoxin B(1), B(2), G(1), PubMed: Safety and efficacy evaluation of aqueous citric acid to degrade B-aflatoxins in maize PubMed: Development of a microwave-assisted-extraction-based method for the determination of aflatoxins B1, G1, B2, and G2 in grains and grain products PubMed: Investigation of aflatoxin contamination in commercial Spanish peanuts PubMed: Determination of aflatoxins B1, B2, G1, G2 and ochratoxin A in animal feed by ultra high-performance liquid chromatography-tandem mass spectrometry PubMed: Surveys of rice sold in Canada for aflatoxins, ochratoxin A and fumonisins PubMed: Determination of aflatoxins in medicinal herbs by high-performance liquid chromatography-tandem mass spectrometry PubMed: Fabrication of a novel nanocomposite based on sol-gel process for hollow fiber-solid phase microextraction of aflatoxins: B1 and B2, in cereals combined with high performane liquid chromatography-diode PubMed: The effect of aflatoxins on the electron transport chain of chloroplasts from Zea mays L. and Pisum sativum L PubMed: Effect of calcium propionate and water activity on growth and aflatoxins production by Aspergillus flavus PubMed: Biocontrol of aflatoxins B1, B2, G1, G2, and fumonisin B1 with 6,7-dimethoxycoumarin, a phytoalexin from Citrus sinensis PubMed: The surface-enhanced Raman spectra of aflatoxins: spectral analysis, density functional theory calculation, detection and differentiation PubMed: [Aflatoxins in food: tests of decontamination of peanut cakes by ionizing treatment] PubMed: A novel broad-specific noncompetitive immunoassay and its application in the determination of total aflatoxins PubMed: [Measurement and levels of aflatoxins in small-scale pressed peanut oil prepared in the Diourbel and Kaolack regions of Senegal] PubMed: Molar absorptivities of aflatoxins B1, B2, G1, and G2 in acetonitrile, methanol, and toluene-acetonitrile (9 + 1) (modification of AOAC Official Method 971.22): collaborative study PubMed: Simple, rapid, and inexpensive cleanup method for quantitation of aflatoxins in important agricultural products by HPLC PubMed: In situ absorption of aflatoxins in rat small intestine PubMed: Determination of selected mycotoxins in mould cheeses with liquid chromatography coupled to tandem with mass spectrometry PubMed: [Optimization of determination of aflatoxins in foods with bromine postcolumn derivatization] PubMed: Liquid chromatographic analysis of aflatoxin using post-column photochemical derivatization: collaborative study PubMed: Evaluation and application of a bioluminescent bacterial genotoxicity test PubMed: Production of aflatoxins B1, B2, G1, and G2 in pure and mixed cultures of Aspergillus parasiticus and Aspergillus flavus PubMed: Determination of aflatoxins B1, B2, G1, and G2 and ochratoxin A in ginseng and ginger by multitoxin immunoaffinity column cleanup and liquid chromatographic quantitation: collaborative study PubMed: A survey using normal-phase high-performance liquid chromatography of aflatoxins in domestic and imported foods in the USSR PubMed: [Fungi producing aflatoxin B1, B2, G1, G2 and ochratoxin A in pre-packaged foods] PubMed: Determination of aflatoxins B1, B2, G1, and G2 in olive oil, peanut oil, and sesame oil PubMed: Determination of aflatoxins in high-pigment content samples by matrix solid-phase dispersion and high-performance liquid chromatography PubMed: In vitro interaction of actinomycetes isolates with Aspergillus flavus: impact on aflatoxins B1 and B2 production PubMed: A survey of the natural occurrence of aflatoxins and zearalenone in Argentine field maize: 1983-1994 PubMed: Incidence and abundance of mycotoxins in maize in Rio Grande do Sul, Brazil PubMed: [Simulation of natural mould growth in processed cheese (author's transl)] PubMed: Comparison of postcolumn derivatization-liquid chromatography with thin-layer chromatography for determination of aflatoxins in naturally contaminated corn PubMed: Enzyme-linked immunosorbent assay of total aflatoxins B1, B2, and G1 in corn: follow-up collaborative study PubMed: Atmospheric pressure photo-ionization liquid chromatography/mass spectrometric determination of aflatoxins in food PubMed: Aflatoxin contamination of sorghum seeds during storage under controlled conditions PubMed: Enzyme-linked immunosorbent assay of aflatoxins B1, B2, and G1 in corn, cottonseed, peanuts, peanut butter, and poultry feed: collaborative study PubMed: Aflatoxin and cyclopiazonic acid production by a sclerotium-producing Aspergillus tamarii strain PubMed: Metabolite of Macrophomina phaseoli that can confuse thin-layer chromatographic identification of aflatoxin B2 PubMed: Production of aflatoxins by strains of the Aspergillus flavus group maintained in ATCC PubMed: Surveillance and control of aflatoxins B1, B2, G1, G2, and M1 in foodstuffs in the Republic of Cyprus: 1992-1996 PubMed: Aspergillus growth and aflatoxin production on black pepper PubMed: The occurrence of aflatoxins in mustard and mustard products PubMed: A survey of aflatoxin levels in peanut meal imported into Poland for animal feedingstuffs PubMed: The role of zinc in the aflatoxigenic potential of Aspergillus flavus NRRL 3251 on foodstuffs PubMed: Aflatoxin production by Aspergillus flavus field isolates PubMed: Determination of aflatoxins in compound feedstuffs containing citrus pulp PubMed: Degradation of aflatoxins in peanut kernels/flour by gaseous ozonation and mild heat treatment PubMed: A survey of ochratoxin A and aflatoxins in domestic and imported beers in Japan by immunoaffinity and liquid chromatography PubMed: Survey of aflatoxin contamination of dried figs grown in Turkey in 1986 PubMed: Aflatoxin-producing potential of Aspergillus flavus strains isolated from Spanish poultry feeds PubMed: Efficiency of different extraction solvent mixtures used in analyses of aflatoxins from a certified peanut meal reference material PubMed: Mould contamination and the influence of water activity and temperature on mycotoxin production by two aspergilli in melon seed PubMed: Determination of aflatoxins in groundnut meal by high-performance liquid chromatography: a comparison of two methods of derivatisation of aflatoxin B1 PubMed: [Study on determination of aflatoxins B1, B2, G1 and G2 in peanuts using OASIS HLB cartridges with post-column derivatization HPLC and fluorescence detection] PubMed: Production and characterization of antibodies cross-reactive with major aflatoxins PubMed: A combinatorial approach to obtain affinity media with binding properties towards the aflatoxins PubMed: International mycotoxin check sample program: Part I. Report on laboratory performance for determination of aflatoxins B1, B2, G1, and G2 in raw peanut meal, deoiled peanut meal, and yellow corn meal PubMed: [Determination of aflatoxins B1, B2, G1, G2 and M1 by high pressure thin layer chromatography] PubMed: High performance thin layer chromatography ELISAGRAM. Application of a multi-hapten immunoassay to analysis of the zearalenone and aflatoxin mycotoxin families PubMed: Determination of aflatoxins by capillary column gas chromatography PubMed: A simple quantitative HPLC method for determination of aflatoxins in cereals and animal feedstuffs using gel permeation chromatography clean-up PubMed: Comparison of four thin-layer chromatographic methods for the determination of aflatoxins in raisins