auraptene

aurapten 2H-1- benzopyran-2-one, 7-((3,7-dimethyl-2,6-octadienyl)oxy)-, (E)- 2H-1- benzopyran-2-one, 7-[(3,7-dimethyl-2,6-octadienyl)oxy]-, (E)- 2H-1- benzopyran-2-one, 7-[[(2E)-3,7-dimethyl-2,6-octadien-1-yl]oxy]- coumarin, 7-[(3,7-dimethyl-2,6-octadienyl)oxy]-, (E)- 7-[(3,7- dimethyl-2,6-octadien-1-yl)oxy]-2H-chromen-2-one 7-[[(2E)-3,7- dimethyl-2,6-octadien-1-yl]oxy]-2H-1-benzopyran-2-one 7-{[(2E)-3,7- dimethyl-2,6-octadien-1-yl]oxy}-2H-chromen-2-one (E)-7-((3,7- dimethyl-2,6-octadienyl)oxy)-2H-1-benzopyran-2-one 7-[(3,7- dimethyl-2,6-octadienyl)oxy]-2H-chromen-2-one 7-((E)-3,7- dimethyl-octa-2,6-dienyloxy)-chromen-2-one (E)-7-((3,7- dimethylocta-2,6-dien-1-yl)oxy)-2H-chromen-2-one 7-{[(2E)-3,7- dimethylocta-2,6-dien-1-yl]oxy}-2H-chromen-2-one 7-[(2E)-3,7- dimethylocta-2,6-dienoxy]chromen-2-one 7-((2E)-3,7- dimethylocta-2,6-dienyloxy)chromen-2-one 7- geranyl oxycoumarin 7- geranyloxycoumarin (E)- meranzin PubMed: Auraptene has the inhibitory property on murine T lymphocyte activation. PubMed: Auraptene increases the production of amyloid-β via c-Jun N-terminal kinase-dependent activation of γ-secretase. PubMed: Antihypertensive effect of auraptene, a monoterpene coumarin from the genus Citrus, upon chronic administration. PubMed: Suppression of mitochondrial respiration with auraptene inhibits the progression of renal cell carcinoma: involvement of HIF-1α degradation. PubMed: Auraptene, a Major Compound of Supercritical Fluid Extract of Phalsak (Citrus Hassaku Hort ex Tanaka), Induces Apoptosis through the Suppression of mTOR Pathways in Human Gastric Cancer SNU-1 Cells. PubMed: Anti-inflammatory effect of auraptene extracted from trifoliate orange (Poncirus trifoliate) on LPS-stimulated RAW 264.7 cells. PubMed: Auraptene suppresses inflammatory responses in activated RAW264 macrophages by inhibiting p38 mitogen-activated protein kinase activation. PubMed: Auraptene Acts as an Anti-Inflammatory Agent in the Mouse Brain. PubMed: Anti-inflammatory and wound healing potential of citrus auraptene. PubMed: Hypotensive activity of auraptene, a monoterpene coumarin from Citrus spp. PubMed: Stimulation of phosphorylation of ERK and CREB by phellopterin and auraptene isolated from Citrusjunos. PubMed: The plant coumarins auraptene and lacinartin as potential multifunctional therapeutic agents for treating periodontal disease. PubMed: Quantitative evaluation of auraptene and umbelliferone, chemopreventive coumarins in citrus fruits, by HPLC-UV-FL-MS. PubMed: Auraptene in the Peels of Citrus kawachiensis (Kawachi Bankan) Ameliorates Lipopolysaccharide-Induced Inflammation in the Mouse Brain. PubMed: Auraptene attenuates gastritis via reduction of Helicobacter pylori colonization and pro-inflammatory mediator production in C57BL/6 mice. PubMed: Effects of Auraptene on IGF-1 Stimulated Cell Cycle Progression in the Human Breast Cancer Cell Line, MCF-7. PubMed: Auraptene regulates gene expression involved in lipid metabolism through PPARα activation in diabetic obese mice. PubMed: Auraptene and its effects on the re-emergence of colon cancer stem cells. PubMed: Anti-inflammatory and neuroprotective effects of auraptene, a citrus coumarin, following cerebral global ischemia in mice. PubMed: Neurotrophic effect of citrus auraptene: neuritogenic activity in PC12 cells. PubMed: Novel prodrugs for the treatment of colonic diseases based on 5-aminosalicylic acid, 4'-geranyloxyferulic acid, and auraptene: biological activities and analytical assays. PubMed: Effects of citrus auraptene (7-geranyloxycoumarin) on hepatic lipid metabolism in vitro and in vivo. PubMed: Auraptene is an inhibitor of cholesterol esterification and a modulator of estrogen receptors. PubMed: Identification, synthesis and quantification of process-related impurities in auraptene. PubMed: Auraptene: a natural biologically active compound with multiple targets. PubMed: Auraptene from Ferula szowitsiana protects human peripheral lymphocytes against oxidative stress. PubMed: Citrus auraptene: a potential multifunctional therapeutic agent for nonalcoholic fatty liver disease. PubMed: Citrus auraptene suppresses cyclin D1 and significantly delays N-methyl nitrosourea induced mammary carcinogenesis in female Sprague-Dawley rats. PubMed: Potential benefits of supplementation with auraptene in cystic fibrosis. PubMed: Suppression of CD74 expression and Helicobacter pylori adhesion by auraptene targeting serum starvation-activated ERK1/2 in NCI-N87 gastric carcinoma cells. PubMed: Evaluation of auraptene content in citrus fruits and their products. PubMed: Immunomodulatory action of citrus auraptene on macrophage functions and cytokine production of lymphocytes in female BALB/c mice. PubMed: Citrus auraptene exerts dose-dependent chemopreventive activity in rat large bowel tumorigenesis: the inhibition correlates with suppression of cell proliferation and lipid peroxidation and with induction of phase II drug-metabolizing enzymes. PubMed: Chemoprevention of 4-nitroquinoline 1-oxide-induced oral carcinogenesis by citrus auraptene in rats. PubMed: Auraptene, a citrus coumarin, inhibits 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion in ICR mouse skin, possibly through suppression of superoxide generation in leukocytes. PubMed: Colorectal cancer chemoprevention by 2 beta-cyclodextrin inclusion compounds of auraptene and 4'-geranyloxyferulic acid. PubMed: Auraptene, a citrus fruit compound, regulates gene expression as a PPARalpha agonist in HepG2 hepatocytes. PubMed: Citrus auraptene targets translation of MMP-7 (matrilysin) via ERK1/2-dependent and mTOR-independent mechanism. PubMed: Suppressing effects of dietary supplementation of the organoselenium 1,4-phenylenebis(methylene)selenocyanate and the Citrus antioxidant auraptene on lung metastasis of melanoma cells in mice. PubMed: Suppression of N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis by dietary feeding of auraptene. PubMed: Citrus auraptene acts as an agonist for PPARs and enhances adiponectin production and MCP-1 reduction in 3T3-L1 adipocytes. PubMed: Dietary administration with prenyloxycoumarins, auraptene and collinin, inhibits colitis-related colon carcinogenesis in mice. PubMed: Protective effects of citrus nobiletin and auraptene in transgenic rats developing adenocarcinoma of the prostate (TRAP) and human prostate carcinoma cells. PubMed: Citrus auraptene inhibits chemically induced colonic aberrant crypt foci in male F344 rats. PubMed: Auraptene decreases the activity of matrix metalloproteinases in dextran sulfate sodium-induced ulcerative colitis in ICR mice. PubMed: Zingiberaceous and citrus constituents, 1'-acetoxychavicol acetate, zerumbone, auraptene, and nobiletin, suppress lipopolysaccharide-induced cyclooxygenase-2 expression in RAW264.7 murine macrophages through different modes of action. PubMed: Effects of selected food phytochemicals in reducing the toxic actions of TCDD and p,p'-DDT in U937 macrophages. PubMed: Metabolism and absorption of auraptene (7-geranyloxylcoumarin) in male SD rats: comparison with 7-ethoxycoumarin. PubMed: Citrus auraptene reduces Helicobacter pylori colonization of glandular stomach lesions in Mongolian gerbils. PubMed: Citrus auraptene suppresses azoxymethane-induced colonic preneoplastic lesions in C57BL/KsJ-db/db mice. PubMed: Suppression of beta-catenin mutation by dietary exposure of auraptene, a citrus antioxidant, in N,N-diethylnitrosamine-induced hepatocellular carcinomas in rats. PubMed: Dietary supplementation of the citrus antioxidant auraptene inhibits N,N-diethylnitrosamine-induced rat hepatocarcinogenesis. PubMed: Suppression by citrus auraptene of phorbol ester-and endotoxin-induced inflammatory responses: role of attenuation of leukocyte activation. PubMed: Apoptogenic activity of auraptene of Zanthoxylum schinifolium toward human acute leukemia Jurkat T cells is associated with ER stress-mediated caspase-8 activation that stimulates mitochondria-dependent or -independent caspase cascade. PubMed: In vitro absorption and metabolism of a citrus chemopreventive agent, auraptene, and its modifying effects on xenobiotic enzyme activities in mouse livers. PubMed: Studies on the constituents of orange oil. I. On the structure of auraptene. PubMed: Potent and selective inhibitors of class A β-lactamase: 7-prenyloxy coumarins. PubMed: Combination of bioautography with HPTLC-MS/NMR: a fast identification of acetylcholinesterase inhibitors from galbanum(†). PubMed: Effects of Bioactive Substances from Citrus on the Central Nervous System and Utilization as Food Material. PubMed: Biological properties and molecular targets of umbelliprenin--a mini-review. PubMed: Semisynthetic studies identify mitochondria poisons from botanical dietary supplements--geranyloxycoumarins from Aegle marmelos. PubMed: [Determination of the active constituents in aurantii fructus from Jiangxi province at different harvest time by HPLC]. PubMed: Comparison of citrus coumarins on carcinogen-detoxifying enzymes in Nrf2 knockout mice. PubMed: Nelumal A, the active principle from Ligularia nelumbifolia, is a novel farnesoid X receptor agonist. PubMed: Simultaneous quantification of polymethoxylated flavones and coumarins in Fructus aurantii and Fructus aurantii immaturus using HPLC-ESI-MS/MS. PubMed: Aggressive mammary carcinoma progression in Nrf2 knockout mice treated with 7,12-dimethylbenz[a]anthracene. PubMed: Development of a quantitative bioassay to assess preventive compounds against inflammation-based carcinogenesis. PubMed: A new cytotoxic coumarin, 7-[(E)-3',7'-dimethyl-6'-oxo-2',7'-octadienyl] oxy coumarin, from the leaves of Zanthoxylum schinifolium. PubMed: Effects of ATRA combined with citrus and ginger-derived compounds in human SCC xenografts. PubMed: Effects of chemopreventive citrus phytochemicals on human P-glycoprotein and multidrug resistance protein 1. PubMed: Sesquiterpene coumarins from Ferula szowitsiana and in vitro antileishmanial activity of 7-prenyloxycoumarins against promastigotes. PubMed: Citrus compounds inhibit inflammation- and obesity-related colon carcinogenesis in mice. PubMed: Cancer-preventive anti-oxidants that attenuate free radical generation by inflammatory cells. PubMed: [Chemical study of citrus plants in the search for cancer chemopreventive agents]. PubMed: Effects of naturally occurring coumarins on hepatic drug-metabolizing enzymes in mice. PubMed: Neuroprotective effect of prenyloxycoumarins from edible vegetables. PubMed: Citrus nobiletin suppresses bone loss in ovariectomized ddY mice and collagen-induced arthritis in DBA/1J mice: possible involvement of receptor activator of NF-kappaB ligand (RANKL)-induced osteoclastogenesis regulation. PubMed: Cancer chemopreventive activity of terpenoid coumarins from Ferula species. PubMed: Umbelliprenin from Ferula szowitsiana inhibits the growth of human M4Beu metastatic pigmented malignant melanoma cells through cell-cycle arrest in G1 and induction of caspase-dependent apoptosis. PubMed: Rapid analysis of gene expression changes caused by liver carcinogens and chemopreventive agents using a newly developed three-dimensional microarray system. PubMed: Inhibition of acetylcholinesterase activity by essential oil from Citrus paradisi. PubMed: Cell proliferation in cancer prevention; effects of preventive agents on estrogen-related endometrial carcinogenesis model and on an in vitro model in human colorectal cells. PubMed: [Studies on the bioactive constituents of Aurantii Fructus Immaturus]. PubMed: Potential anti-allergic acridone alkaloids from the roots of Atalantia monophylla. PubMed: Monoamine oxidase inhibitory coumarins from the aerial parts of Dictamnus albus. PubMed: Inhibition of cell proliferation by nobiletin, a dietary phytochemical, associated with apoptosis and characteristic gene expression, but lack of effect on early rat hepatocarcinogenesis in vivo. PubMed: Phytochemical analysis of anti-atherogenic constituents of Xue-Fu-Zhu-Yu-Tang using HPLC-DAD-ESI-MS. PubMed: Synthesis and anti-inflammatory activity of natural and semisynthetic geranyloxycoumarins. PubMed: Effects of selected food factors with chemopreventive properties on combined lipopolysaccharide- and interferon-gamma-induced IkappaB degradation in RAW264.7 macrophages. PubMed: Further investigation of the modifying effect of various chemopreventive agents on apoptosis and cell proliferation in human colon cancer cells.