alpha-chloralose
1,2-O-(2,2,2-trichloroethylidene)-alpha-D-glucofuranose
Identification
| Name | alpha-chloralose |
| IUPAC | 1-[(2R,5R,6S,6aR)-6-hydroxy-2-(trichloromethyl)-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl]ethane-1,2-diol |
| CAS Number | 15879-93-3 |
| EINECS | 240-016-7 |
| FDA UNII | 238BZ29MUE |
| Molecular Formula | C8 H11 Cl3 O6 |
| Molecular Weight | 309.52687000 |
| MDL Number | MFCD00005542 |
| Beilstein | 0085418 |
| XlogP3 | 1.00 (est) |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 182.00 °C. @ 760.00 mm Hg |
| Boiling Point | 504.41 °C. @ 760.00 mm Hg (est) |
| Flash Point | 498.00 °F. TCC ( 258.90 °C. ) (est) |
| logP (o/w) | 1.020 |
| Soluble in | water, 4440 mg/L @ 15 °C (exp) |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | oral-bird - wild LD50 9 mg/kg |
| Dermal Toxicity | subcutaneous-rat LDLo 200 mg/kg |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | herbicides / pesticides |
| Recommendation for alpha-chloralose usage levels up to | not for fragrance use. |
| Recommendation for alpha-chloralose flavor usage levels up to | not for flavor use. |
Penta International Corporation
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Potential Uses
Natural Occurrence
Synonyms
anhydroglucochloral
(R)-1-((2R,3aR,5R,6S,6aR)-6-
hydroxy-2-(trichloromethyl)tetrahydrofuro[2,3-d][1,3]dioxol-5-yl)ethane-1,2-diol
1,2-O-(2,2,2-
trichloroethylidene)-alpha-D-glucofuranose
1-[(2R,5R,6S,6aR)-6-hydroxy-2-(
trichloromethyl)-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl]ethane-1,2-diol
PubMed:
Hyponeophagia: a measure of anxiety in the mouse.
PubMed:
On the use of α-chloralose for repeated BOLD fMRI measurements in rats.
PubMed:
Acute inhibition of the hypothalamic paraventricular nucleus decreases renal sympathetic nerve activity and arterial blood pressure in water-deprived rats.
PubMed:
Alpha-chloralose immobilization of rock doves in Ohio.
PubMed:
Isolation of bilobalide and ginkgolide A from Ginkgo biloba L. shorten the sleeping time induced in mice by anesthetics.
PubMed:
Adrenal sympathetic efferent nerve and catecholamine secretion excitation caused by capsaicin in rats.
PubMed:
Effect of capsaicin pretreatment on capsaicin-induced catecholamine secretion from the adrenal medulla in rats.
PubMed:
The effects of chronic two-fold dietary vitamin E supplementation on subarachnoid hemorrhage-induced brain hypoperfusion.