ammonium citrate dibasic

diammonium 3-carboxy-3-hydroxypentanedioate

CAS: 3012-65-5 C6 H14 N2 O7 MW: 226.18598000

Identification

Nameammonium citrate dibasic
IUPACdiazanium 3-carboxy-3-hydroxypentanedioate
CAS Number3012-65-5
EINECS221-146-3
FDA UNIIN9BUG430K8
Molecular FormulaC6 H14 N2 O7
Molecular Weight226.18598000
MDL NumberMFCD00013068
Beilstein4925760

Regulatory

FDA/DG SANTE Petitions, Reviews, Notices184.1140
FDA Mainterm (SATF)3012-65-5 ; AMMONIUM CITRATE, DIBASIC
FDA RegulationFDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 309.00 to 310.00 °C. @ 760.00 mm Hg
Vapor Pressure 0.000057 mmHg @ 25.00 °C. (est)
Vapor Density 1.8 ( Air = 1 )
Flash Point 311.00 °F. TCC ( 155.00 °C. )
logP (o/w) -2.840
Soluble in water, 1e+006 mg/L @ 25 °C (est)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesbuffering agents

No sensory data available

Safety Information

European informationMost important hazard(s):
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorystabilizing agents
Recommendation for ammonium citrate dibasic usage levels up tonot for fragrance use.
Recommendation for ammonium citrate dibasic flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

ammonium citrate dibasic ammonium citrate, dibasic ammonium hydrogen citrate ammonium hydrogencitrate ammonium monohydrogen citrate ammonium monohydrogencitrate ammoniumcitratedibasic citric acid diammonium salt citric acid, diammonium salt diammonium 2-(carboxymethyl)-2-hydroxybutanedioate diammonium 2-(carboxymethyl)-2-hydroxysuccinate diammonium 2-hydroxy-1,2,3-propanetricarboxylate diammonium 3-carboxy-3-hydroxypentanedioate diammonium citrate diammonium hydrogen 2-hydroxypropane-1,2,3-tricarboxylate diammonium hydrogen citrate diazanium 3-carboxy-3-hydroxypentanedioate 2- hydroxy-1,2,3-propanetricarboxylic acid diammonium salt 2- hydroxy-1,2,3-propanetricarboxylic acid, diammonium salt 1,2,3- propanetricarboxylic acid, 2-hydroxy-, ammonium salt 1,2,3- propanetricarboxylic acid, 2-hydroxy-, diammonium salt PubMed: Injectability and mechanical properties of magnesium phosphate cements. PubMed: A sialylation study of mouse brain gangliosides by MALDI a-TOF and o-TOF mass spectrometry. PubMed: Effect of the addition of diammonium citrate to alpha-cyano-4-hydroxycinnamic acid (CHCA) matrix for the detection of phosphorylated peptide in phosphorylation reactions using cell and tissue lysates. PubMed: Analytical procedure for the simultaneous voltammetric determination of trace metals in food and environmental matrices. Critical comparison with atomic absorption spectroscopic measurements. PubMed: Development of a MALDI-TOF-MS method to identify and quantify butyrylcholinesterase inhibition resulting from exposure to organophosphate and carbamate pesticides. PubMed: Detection of hypoxia-related proteins in medaka (Oryzias latipes) brain tissue by difference gel electrophoresis and de novo sequencing of 4-sulfophenyl isothiocyanate-derivatized peptides by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. PubMed: MALDI analysis of oligonucleotides directly from montmorillonite. PubMed: Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry of 4-sulfophenyl isothiocyanate-derivatized peptides on AnchorChip sample supports using the sodium-tolerant matrix 2,4,6-trihydroxyacetophenone and diammonium citrate. PubMed: Overlapping voltammetric peaks--an analytical procedure for simultaneous determination of trace metals. Application to food and environmental matrices. PubMed: Enhanced ionization of phosphorylated peptides during MALDI TOF mass spectrometry. PubMed: Improvement in the detection of low concentration protein digests on a MALDI TOF/TOF workstation by reducing alpha-cyano-4-hydroxycinnamic acid adduct ions. PubMed: Analytical procedure for the simultaneous voltammetric determination of toxic metals in dialysis fluids. PubMed: Effect of additives on electrokinetic properties of colloidal alumina suspension. PubMed: Speciation of nickel in airborne particulate matter by means of sequential extraction in a micro flow system and determination by graphite furnace atomic absorption spectrometry and inductively coupled plasma mass spectrometry. PubMed: Adverse effects of excess DL-methionine in calves with different body weights. PubMed: Absence of limiting amino acids in calves fed a corn and soybean meal diet past three months of age. PubMed: Enhanced detection of phosphopeptides in matrix-assisted laser desorption/ionization mass spectrometry using ammonium salts. PubMed: Matrix-assisted laser desorption/ionisation mass spectrometry of transfer ribonucleic acids isolated from yeast. PubMed: Correlation of biological value of feed phosphates with their solubility in water, dilute hydrogen chloride, dilute citric acid, and neutral ammonium citrate. PubMed: Utilization of dietary diammonium citrate by germ-free chicks. PubMed: Effect of chemicals on fungal alpha-amylase activity. PubMed: Production of succinic Acid from citric Acid and related acids by lactobacillus strains. PubMed: 15N transfer from 15N-urea and 15N-diammonium citrate into tissue proteins in normal cats fed with an optimal protein diet. PubMed: Antagonism of arginine by excess dietary lysine in the growing dog. PubMed: The effects of high dietary protein and nitrogen levels on the preformed methyl group requirement and methionine-induced growth depression in chicks. PubMed: Incorporation of nitrogen-15 from dietary [15N] diammonium citrate into amino acids of liver and muscle proteins in germfree and specific-pathogen-free neonatal pigs. PubMed: Diammonium citrate addition to a diet restricted non-essential amino acids for young pigs. PubMed: Role of intestinal flora on incorporation of 15N from dietary, 15N-urea, and 15N-diammonium citrate into tissue proteins in pigs. PubMed: Effects of dietary histidine and arginine on plasma amino acid and urea concentrations of men fed a low nitrogen diet. PubMed: Effects of dietary histidine and arginine on nitrogen retention of men. PubMed: The use of growth and liver aspartate aminotransferase to assess the effect of source of non-essential nitrogen on pyridoxine depletion, repletion and requirements of chicks. PubMed: Is L-glutamic acid nutritionally a dispensable amino acid for the young chick? PubMed: Nonprotein nitrogen for growing chickens. PubMed: Growth inhibition of broilers by diammonium citrate. PubMed: Egg production responses of Coturnix quail to dietary additions of nitrogen in the form of amino acids, diammonium citrate and intact protein. PubMed: Comparison of urea and diammonium citrate as sources of nonspecific nigrogen for human adults. PubMed: Effect of urea and diammonium citrate on fecal components of chicken hens. PubMed: Enzyme studies with the livers of chicks fed semi-synthetic diets containing crystalline amino acids and diammonium citrate. PubMed: Effects on chick growth of adding glycine, proline, glutamic acid or diammonium citrate to diets containing crystalline essential amino acids. PubMed: Diammonium citrate and diammonium phosphate as sources of dietary nitrogen for growing-finishing swine. PubMed: Some effects of nicotinamide, diammonium citrate and urea as supplements to low-protein diets. PubMed: Diammonium citrate and diammonium phosphate as sources of dietary nitrogen for growing-finishing swine.