benzyl butyl phthalate

phthalic acid, benzyl butyl ester

CAS: 85-68-7 C19 H20 O4 MW: 312.36520000

Identification

Namebenzyl butyl phthalate
CAS Number85-68-7
EINECS201-622-7
FDA UNIIYPC4PJX59M
Molecular FormulaC19 H20 O4
Molecular Weight312.36520000
MDL NumberMFCD00009440
Nikkaji NumberJ45.539C
Beilstein2062204
XlogP34.90 (est)

Regulatory

DG SANTE Food Contact Materialsphthalic acid, benzyl butyl ester
FDA Mainterm (IAUFC)85-68-7 ; BUTYL BENZYL PHTHALATE
FDA RegulationFDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS

Physical Properties

Appearance colorless clear liquid (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 1.10000 @ 25.00 °C.
Melting Point -35.00 °C. @ 760.00 mm Hg
Boiling Point 370.00 °C. @ 760.00 mm Hg, 250.00 °C. @ 22.50 mm Hg
Vapor Density 10.8 ( Air = 1 )
Flash Point > 230.00 °F. TCC ( > 110.00 °C. )
logP (o/w) 4.730
Soluble in water, 2.69 mg/L @ 25 °C (exp)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesnot used anymore

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityoral-rat LD50 2330 mg/kg
Dermal Toxicityskin-rat LD50 6700 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryindirect food additives: adhesives and components of coatings
Recommendation for benzyl butyl phthalate usage levels up tonot for fragrance use.
Recommendation for benzyl butyl phthalate flavor usage levels up tonot for flavor use.

Penta International Corporation

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Potential Uses

film formers

Natural Occurrence

not found in nature

Synonyms

1,2- benzenedicarboxylic acid benzyl butylester 1,2- benzenedicarboxylic acid butyl phenylmethyl ester 1,2- benzenedicarboxylic acid, butyl phenylmethyl ester 2-O- benzyl 1-O-butyl benzene-1,2-dicarboxylate benzyl butyl benzene-1,2-dicarboxylate benzyl N-butyl phthalate benzylbutylphthalate butyl benzyl phthalate N- butyl benzyl phthalate butyl phenyl methyl 1,2-benzene dicarboxylate butyl phenylmethyl 1,2-benzenedicarboxylate butylbenzyl phthalate butylbenzylphthalate palatinol BB phthalic acid benzyl butyl ester phthalic acid benzyl N-butyl ester phthalic acid, benzyl butyl ester santicizer 160 sicol 160 unimoll BB PubMed: The influence of resource strategies on childhood phthalate exposure-The role of REACH in a zero waste society. PubMed: Contamination of wines and spirits by phthalates: types of contaminants present, contamination sources and means of prevention. PubMed: Benzyl butyl phthalate exposure impairs learning and memory and attenuates neurotransmission and CREB phosphorylation in mice. PubMed: Findings of 2731 suspected phthalate-tainted foodstuffs during the 2011 phthalates incident in Taiwan. PubMed: Occurrence of Di-(2-ethylhexyl) adipate and phthalate plasticizers in samples of meat, fish, and cheese and their packaging films. PubMed: Intake estimates of phthalate esters for South Delhi population based on exposure media assessment. PubMed: Childhood exposure to DEHP, DBP and BBP under existing chemical management systems: a comparative study of sources of childhood exposure in Korea and in Denmark. PubMed: Determination and pharmacokinetics of di-(2-ethylhexyl) phthalate in rats by ultra performance liquid chromatography with tandem mass spectrometry. PubMed: Chronic exposure to benzyl butyl phthalate (BBP) alters social interaction and fear conditioning in male adult rats: alterations in amygdalar MeCP2, ERK1/2 and ERα. PubMed: Phthalate metabolites in obese individuals undergoing weight loss: Urinary levels and estimation of the phthalates daily intake. PubMed: Determination of phthalate diesters in foods. PubMed: Phthalates in indoor dust in Kuwait: implications for non-dietary human exposure. PubMed: Detection of migration of phthalates from agglomerated cork stoppers using HPLC-MS/MS. PubMed: Occurrence and profiles of phthalates in foodstuffs from China and their implications for human exposure. PubMed: Phthalates residues in plastic bottled waters. PubMed: Determination of phthalate esters in soil by microemulsion electrokinetic chromatography coupled with accelerated solvent extraction. PubMed: Alkylphenols and phthalates in bottled waters. PubMed: Reproductive and developmental toxicity of phthalates. PubMed: Determination of phthalates in fruit jellies by dispersive SPE coupled with HPLC-MS. PubMed: Survey of phthalate levels in Italian oily foods contained in glass jars with PVC gaskets. PubMed: Phthalate exposure through food and consumers' risk perception of chemicals in food. PubMed: Simultaneous screening and determination eight phthalates in plastic products for food use by sonication-assisted extraction/GC-MS methods. PubMed: Plastic components affect the activation of the aryl hydrocarbon and the androgen receptor. PubMed: Determination of phthalates and adipate in bottled water by headspace solid-phase microextraction and gas chromatography/mass spectrometry. PubMed: Analysis of consumer cosmetic products for phthalate esters. PubMed: Determination of phthalates in milk and milk products by liquid chromatography/tandem mass spectrometry. PubMed: Diisobutyl phthalate has comparable anti-androgenic effects to di-n-butyl phthalate in fetal rat testis. PubMed: NTP-CERHR Monograph on the Potential Human Reproductive and Developmental Effects of Butyl Benzyl Phthalate (BBP). PubMed: Phthalates inhibit tamoxifen-induced apoptosis in MCF-7 human breast cancer cells. PubMed: Decreased anogenital distance and increased incidence of undescended testes in fetuses of rats given monobenzyl phthalate, a major metabolite of butyl benzyl phthalate. PubMed: Investigation of the adjuvant and immuno-suppressive effects of benzyl butyl phthalate, phthalic acid and benzyl alcohol in a murine injection model. PubMed: Generation of anticalins with specificity for a nonsymmetric phthalic acid ester. PubMed: Effects on development of the reproductive system in male offspring of rats given butyl benzyl phthalate during late pregnancy. PubMed: Effects of endocrine disrupting chemicals on the microtubule network in Chinese hamster V79 cells in culture and in Sertoli cells in rats. PubMed: Effect of butyl benzyl phthalate in Sprague-Dawley rats after gavage administration: a two-generation reproductive study. PubMed: Metabolism of n-butyl benzyl phthalate in the female Wistar rat. Identification of new metabolites. PubMed: The plasticizer benzyl butyl phthalate (BBP) inhibits 7,12-dimethylbenz[a]anthracene (DMBA)-induced rat mammary DNA adduct formation and tumorigenesis. PubMed: Developmental toxicity of mono-n-benzyl phthalate, one of the major metabolites of the plasticizer n-butyl benzyl phthalate, in rats. PubMed: Evaluation of the OECD 421 reproductive toxicity screening test protocol using butyl benzyl phthalate. PubMed: Developmental toxicity evaluation of diethyl and dimethyl phthalate in rats. PubMed: Embryolethality and teratogenicity of butyl benzyl phthalate in rats. PubMed: Teratogenic evaluation of butyl benzyl phthalate in rats by gastric intubation. PubMed: Effect of period of exposure on the developmental toxicity of butyl benzyl phthalate in rats. PubMed: Evaluation of the embryolethality of butyl benzyl phthalate by conventional and pair-feeding studies in rats. PubMed: Evaluation of the teratogenic potential of the plasticizer butyl benzyl phthalate in rats. PubMed: The use of multivariate analysis to compare peroxisome induction data on phthalate esters in rats.