Synonyms
ammonium, benzyldiethyl((2,6-xylylcarbamoyl)methyl)-, benzoate
benzenemethanaminium, N-(2-((2,6-dimethylphenyl)amino)-2-oxoethyl)-N,N-diethyl-, benzoate
benzenemethanaminium, N-[2-[(2,6-dimethylphenyl)amino]-2-oxoethyl]-N,N-diethyl-, benzoate
benzenemethanaminium, N-[2-[(2,6-dimethylphenyl)amino]-2-oxoethyl]-N,N-diethyl-, benzoate (1:1)
benzyl diethyl (2,6-xylyl carbamoyl methyl) ammonium benzoate
benzyl-[(2,6-dimethylphenylcarbamoyl)methyl]diethylammonium benzoate
benzyl-[2-(2,6-dimethylanilino)-2-oxoethyl]-diethylazanium benzoate
N-
benzyl-2-[(2,6-dimethylphenyl)amino]-N,N-diethyl-2-oxoethanaminium benzoate
benzyldiethyl((2,6-xylylcarbamoyl)methyl)ammonium benzoate
benzyldiethyl(2,6-xylyl- carbamoyl- methyl)- ammonium benzoate
benzyldiethyl[(2,6-xylylcarbamoyl)methyl]ammonium benzoate
bitrex
denatoniumbenzoate
N,N-
diethyl-N-[(2,6-dimethylphenyl- carbamoyl)- methyl]- benzyl- ammonium benzoate
N-(2-((2,6-
dimethyl phenyl)amino)-2-oxoethyl)-N,N-diethyl benzene methanaminium benzoate
N-(2-((2,6-
dimethylphenyl)amino)-2-oxoethyl)-N,N-diethylbenzeneme- thanaminium benzoate
((2,6-
xylylcarbamoyl)methyl)diethyl benzyl ammonium benzoate
PubMed:
Age-related differences in bitter taste and efficacy of bitter blockers.
PubMed:
Denatonium induces secretion of glucagon-like peptide-1 through activation of bitter taste receptor pathways.
PubMed:
Intragastric gavage of denatonium benzoate acutely induces the neuronal activation in the nucleus of solitary tract via the vagal afferent pathway.
PubMed:
Effect of five taste ligands on the release of CCK from an enteroendocrine cell line, STC-1.
PubMed:
6-methoxyflavanones as bitter taste receptor blockers for hTAS2R39.
PubMed:
Detection of Denatonium Benzoate (Bitrex) Remnants in Noncommercial Alcoholic Beverages by Raman Spectroscopy.
PubMed:
Bitter and sweet taste receptors regulate human upper respiratory innate immunity.
PubMed:
A Comparative Evaluation of Condylar Guidance Value from Radiograph with Interocclusal Records made During Jaw Relation and Try-in: A Pilot Study.
PubMed:
A novel human receptor involved in bitter tastant detection identified using Dictyostelium discoideum.
PubMed:
Occupational hazards associated with endoscope high-level disinfection: case vignettes, review of literature and recommendations for mitigation.
PubMed:
The human bitter taste receptor TAS2R10 is tailored to accommodate numerous diverse ligands.
PubMed:
The sugar meal of the African malaria mosquito Anopheles gambiae and how deterrent compounds interfere with it: a behavioural and neurophysiological study.
PubMed:
Future bronchodilator therapy: a bitter pill to swallow?
PubMed:
The bitter taste receptor (TAS2R) agonists denatonium and chloroquine display distinct patterns of relaxation of the guinea pig trachea.
PubMed:
Bitter taste stimuli induce differential neural codes in mouse brain.
PubMed:
Constitutively active mutant gives novel insights into the mechanism of bitter taste receptor activation.
PubMed:
Investigating the effect of emetic compounds on chemotaxis in Dictyostelium identifies a non-sentient model for bitter and hot tastant research.
PubMed:
Ongoing ingestive behavior is rapidly suppressed by a preabsorptive, intestinal "bitter taste" cue.
PubMed:
Functional bitter taste receptors are expressed in brain cells.
PubMed:
Responses of single chorda tympani taste fibers of the calf (Bos taurus).
PubMed:
Nasal chemosensory cells use bitter taste signaling to detect irritants and bacterial signals.
PubMed:
Residual chemosensory capabilities in double P2X2/P2X3 purinergic receptor null mice: intraoral or postingestive detection?
PubMed:
Signalling mechanisms in mouse bitter responsive taste cells.
PubMed:
Gustatory responsiveness to six bitter tastants in three species of nonhuman primates.
PubMed:
Gustation in fish: search for prototype of taste perception.
PubMed:
Central Fos expression and conditioned flavor avoidance in rats following intragastric administration of bitter taste receptor ligands.
PubMed:
UV-vis spectrophotometric method for the quantitation of all the components of Italian general denaturant and its application to check the conformity of alcohol samples.
PubMed:
Construction of a taste-blind medaka fish and quantitative assay of its preference-aversion behavior.
PubMed:
Final report of the safety assessment of Alcohol Denat., including SD Alcohol 3-A, SD Alcohol 30, SD Alcohol 39, SD Alcohol 39-B, SD Alcohol 39-C, SD Alcohol 40, SD Alcohol 40-B, and SD Alcohol 40-C, and the denaturants, Quassin, Brucine Sulfate/Brucine, and Denatonium Benzoate.
PubMed:
The impact of bittering agents on suicidal ingestions of antifreeze.
PubMed:
Adverse reactions associated with respirator fit testing of healthcare workers in British Columbia, Canada: a review of compensation claim cases.
PubMed:
Nasal solitary chemoreceptor cell responses to bitter and trigeminal stimulants in vitro.
PubMed:
Responses of the ciliates tetrahymena and paramecium to vertebrate odorants and tastants.
PubMed:
A non-invasive method for ending thumb- and fingersucking habits.
PubMed:
Intragastric infusion of denatonium conditions flavor aversions and delays gastric emptying in rodents.
PubMed:
The taste transduction channel TRPM5 is a locus for bitter-sweet taste interactions.
PubMed:
Role of CCK1 and Y2 receptors in activation of hindbrain neurons induced by intragastric administration of bitter taste receptor ligands.
PubMed:
Riboflavin-binding protein is a novel bitter inhibitor.
PubMed:
Predators' toxin burdens influence their strategic decisions to eat toxic prey.
PubMed:
Broad tuning of the human bitter taste receptor hTAS2R46 to various sesquiterpene lactones, clerodane and labdane diterpenoids, strychnine, and denatonium.
PubMed:
Characterization of ligands for fish taste receptors.
PubMed:
Simulated workplace protection factors for half-facepiece respiratory protective devices.
PubMed:
Single neurons in the nucleus of the solitary tract respond selectively to bitter taste stimuli.
PubMed:
Comparison of performance of three different types of respiratory protection devices.
PubMed:
Bitter stimuli induce Ca2+ signaling and CCK release in enteroendocrine STC-1 cells: role of L-type voltage-sensitive Ca2+ channels.
PubMed:
Errors associated with three methods of assessing respirator fit.
PubMed:
Trpm5 null mice respond to bitter, sweet, and umami compounds.
PubMed:
Differential covariation in taste responsiveness to bitter stimuli in rats.
PubMed:
Chemotaxis of the nematode Caenorhabditis elegans toward cycloheximide and quinine hydrochloride.
PubMed:
Acute ethanol intoxication after consumption of hairspray.
PubMed:
G-protein-dependent and -independent pathways in denatonium signal transduction.
PubMed:
PLCbeta2-independent behavioral avoidance of prototypical bitter-tasting ligands.
PubMed:
Bitterness suppression with zinc sulfate and na-cyclamate: a model of combined peripheral and central neural approaches to flavor modification.
PubMed:
Neural representation of bitter taste in the nucleus of the solitary tract.
PubMed:
Inbred mouse strains C57BL/6J and DBA/2J vary in sensitivity to a subset of bitter stimuli.
PubMed:
Haplotypes at the Tas2r locus on distal chromosome 6 vary with quinine taste sensitivity in inbred mice.
PubMed:
Genomic organization, expression, and function of bitter taste receptors (T2R) in mouse and rat.
PubMed:
Characterization of bitter taste responses of intestinal STC-1 cells.
PubMed:
Umami taste responses are mediated by alpha-transducin and alpha-gustducin.
PubMed:
Identification of ligands for two human bitter T2R receptors.
PubMed:
Diverse bitter stimuli elicit highly similar patterns of Fos-like immunoreactivity in the nucleus of the solitary tract.
PubMed:
Fitting characteristics of eighteen N95 filtering-facepiece respirators.
PubMed:
Was it necessary to add Bitrex (denatonium benzoate) to automotive products?
PubMed:
Saccharin stimulates the "deterrent" cell in the blowfly: behavioral and electrophysiological evidence.
PubMed:
The distinctiveness of ionic and nonionic bitter stimuli.
PubMed:
Role of the G-protein subunit alpha-gustducin in taste cell responses to bitter stimuli.
PubMed:
A psychophysical investigation of binary bitter-compound interactions.
PubMed:
Comparison of the responses of the chorda tympani and glossopharyngeal nerves to taste stimuli in C57BL/6J mice.
PubMed:
Partial rescue of taste responses of alpha-gustducin null mice by transgenic expression of alpha-transducin.
PubMed:
Comparison of five methods for fit-testing N95 filtering-facepiece respirators.
PubMed:
Rats fail to discriminate quinine from denatonium: implications for the neural coding of bitter-tasting compounds.
PubMed:
Covariation in individuals' sensitivities to bitter compounds: evidence supporting multiple receptor/transduction mechanisms.
PubMed:
Effect of compound sequence on bitterness enhancement.
PubMed:
Bitter taste transduced by PLC-beta(2)-dependent rise in IP(3) and alpha-gustducin-dependent fall in cyclic nucleotides.
PubMed:
Taste receptor cells that discriminate between bitter stimuli.
PubMed:
Cellular responses of NG108-15 and SK-N-MC lines to sweet and bitter tastants as measured by extracellular acidification rates.
PubMed:
Comparison of methyl anthranilate and denatonium benzoate as aversants for learning in chicks.
PubMed:
Oregon's Toxic Household Products Law.
PubMed:
G protein betagamma complexes in circumvallate taste cells involved in bitter transduction.
PubMed:
Capability of respirator wearers to detect aerosolized qualitative fit test agents (sweetener and Bitrex) with known fixed leaks.
PubMed:
T2Rs function as bitter taste receptors.
PubMed:
Comparison of N95 disposable filtering facepiece fits using bitrex qualitative and TSI Portacount quantitative fit testing.
PubMed:
Blocking taste receptor activation of gustducin inhibits gustatory responses to bitter compounds.
PubMed:
Transduction for sweet taste of saccharin may involve both inositol 1,4,5-trisphosphate and cAMP pathways in the fungiform taste buds in C57BL mice.
PubMed:
Patch clamp recording of the responses to three bitter stimuli in mouse taste cells.
PubMed:
Training and characterization of a quinine taste discrimination in rhesus monkeys.
PubMed:
Identification of a phospholipase C beta subtype in rat taste cells.
PubMed:
Flavor avoidance learning and its implications in reducing strychnine baiting hazards to nontarget animals.
PubMed:
Physico-chemical characterization of human von Ebner gland protein expressed in Escherichia coli: implications for its physiological role.
PubMed:
Increase in inositol 1,4,5-triphosphate levels of the fungiform papilla in response to saccharin and bitter substances in mice.
PubMed:
Responses of cultured rat trigeminal ganglion neurons to bitter tastants.
PubMed:
Analysis of denatonium benzoate in Oregon consumer products by HPLC.
PubMed:
Quinine suppression of single facial taste fiber responses in the channel catfish.
PubMed:
Response of domestic chicks to methyl anthranilate odour
PubMed:
Bitter taste transduction of denatonium in the mudpuppy Necturus maculosus.
PubMed:
Neural responses to bitter compounds in rats.
PubMed:
Response of pigs to bitter-tasting compounds.
PubMed:
Primate sense of taste: behavioral and single chorda tympani and glossopharyngeal nerve fiber recordings in the rhesus monkey, Macaca mulatta.
PubMed:
Transduction of bitter and sweet taste by gustducin.
PubMed:
Rapid kinetics of second messenger production in bitter taste.
PubMed:
Development of a new qualitative test for fit testing respirators.
PubMed:
An evaluation of repellents to suppress browsing by possums.
PubMed:
Bittering agents: their potential application in reducing ingestions of engine coolants and windshield wash.
PubMed:
Coupling of bitter receptor to phosphodiesterase through transducin in taste receptor cells.
PubMed:
Bitter taste in single chorda tympani taste fibers from chimpanzee.
PubMed:
Denatonium bitter tasting among transgenic mice expressing rat von Ebner's gland protein.
PubMed:
Generation of inositol phosphates in bitter taste transduction.
PubMed:
Genetics of bitter perception in mice.
PubMed:
Taste perception of bitter compounds in young and elderly persons: relation to lipophilicity of bitter compounds.
PubMed:
Response latency of gerbils and hamsters to nuts flavoured with bitter-tasting substances.
PubMed:
Tolerance of bitter compounds by an herbivore,Cavia porcellus.
PubMed:
The role of aversive bittering agents in the prevention of pediatric poisonings.
PubMed:
The effect of sweeteners on bitter taste in young and elderly subjects.
PubMed:
Denatonium benzoate as a deterrent to ingestion of toxic substances: toxicity and efficacy.
PubMed:
Relationships between ingestion and gustatory perception of caffeine.
PubMed:
Denatonium benzoate: review of efficacy and safety.
PubMed:
Plastic membrane ion-selective electrode for the determination of denatonium benzoate (Bitrex).
PubMed:
Taste reactivity in the hamster.
PubMed:
Bittering agents in the prevention of accidental poisoning: children's reactions to denatonium benzoate (Bitrex).
PubMed:
A simple method for reducing autotomy in rats after peripheral nerve lesions.
PubMed:
A method for isolating and patch-clamping single mammalian taste receptor cells.
PubMed:
Drinking drivers in Sweden who consume denatured alcohol preparations: an analytical-toxicological study.
PubMed:
The problems of taste in placebo matching: an evaluation of zinc gluconate for the common cold.
PubMed:
Research on the effectiveness of denatonium benzoate as a deterrent to liquid detergent ingestion by children.
PubMed:
Contact urticaria and asthma from denatonium benzoate (Bitrex).