beta-ecdysone
viticosterone
Identification
| Name | beta-ecdysone |
| CAS Number | 5289-74-7 |
| FDA UNII | 779A7KPL0Y |
| Molecular Formula | C27 H44 O7 |
| Molecular Weight | 480.64208000 |
| MDL Number | MFCD00036740 |
| Beilstein | 1917578 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 702.06 °C. @ 760.00 mm Hg (est) |
| Flash Point | 738.00 °F. TCC ( 392.40 °C. ) (est) |
| logP (o/w) | -0.270 (est) |
| Soluble in | water, 353.1 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | intraperitoneal-mouse LD50 6400 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for beta-ecdysone usage levels up to | not for fragrance use. |
| Recommendation for beta-ecdysone flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
commisterone
crustecdyson
crustecdysone
b-
ecdysone
ecdysteron
ecdysterone
(22R)-2-beta,3-beta,14,20,22,25-
hexahydroxy-5-beta-cholest-7-en-6-one
20-
hydroxyecdysone
polypodine A
(2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-
trihydroxy-10,13-dimethyl-17-[(2S,3R)-2,3,6-trihydroxy-6-methylheptan-2-yl]-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one
viticosterone
PubMed:
Phytochemical analysis of Pfaffia glomerata inflorescences by LC-ESI-MS/MS.
PubMed:
[Chemical constituents from Ajuga nipponensis].
PubMed:
Comprehensive study of the phenolics and saponins from Helleborus niger L. Leaves and stems by liquid chromatography/tandem mass spectrometry.
PubMed:
Ecdysteroids from the flowers of Aerva javanica.
PubMed:
[Research on chemical constituents of xuefu zhuyu decoction].
PubMed:
Beta-ecdysone has bone protective but no estrogenic effects in ovariectomized rats.
PubMed:
Beneficial effects of beta-Ecdysone on the joint, epiphyseal cartilage tissue and trabecular bone in ovariectomized rats.
PubMed:
Identification of radical scavenging compounds in Rhaponticum carthamoides by means of LC-DAD-SPE-NMR.
PubMed:
A new phytosterone from Achyranthes bidentata B1.
PubMed:
Spatially discrete, light-driven protein expression.
PubMed:
A new phytosterone from Cyanotis arachnoidea.
PubMed:
Cell-autonomous requirement of the USP/EcR-B ecdysone receptor for mushroom body neuronal remodeling in Drosophila.
PubMed:
Drosophila EcR-B ecdysone receptor isoforms are required for larval molting and for neuron remodeling during metamorphosis.
PubMed:
Neither enhanced removal of cyclobutane pyrimidine dimers nor strand-specific repair is found after transcription induction of the beta 3-tubulin gene in a Drosophila embryonic cell line Kc.
PubMed:
Immunomodulating effects of the hydrolysis products of formosanin C and beta-ecdysone from Paris formosana Hayata.
PubMed:
[Androgen-like and anabolic action of Antheraea pernyi Guerin-Meneville Pas].
PubMed:
[Steroidal saponins from Asparagus filicinus].
PubMed:
Induction of apolysis and cuticle formation in female Ornithodoros parkeri (Acari: Argasidae) by hemocoelic injections of beta-ecdysone.
PubMed:
Acetylcholinesterase activity in an Aedes aegypti cell line.
PubMed:
Arachnid oenocytes: ecdysone synthesis in the legs of harvestmen (Opilionidae).
PubMed:
Pattern of peptide synthesis in Drosophila cell lines and their hybrids.
PubMed:
Acetylcholinesterase induction by beta-ecdysone in Drosophila cell lines and their hybrids.
PubMed:
Preparation of an ecdysone immunogen for radioimmunoassay work.
PubMed:
Morphogenesis of mechanoreceptor and epidermal cells of crickets during the last instar, and its relation to molting-hormone level.
PubMed:
Tubulin content and synthesis in differentiating Drosophila cells in culture.
PubMed:
Inhibitory effect of beta-ecdysone on protein synthesis by blowfly fat body in vitro.
PubMed:
[Dipetalonema dessetae--Aedes aegypti: study of the infected adipose tissue (author's transl)].
PubMed:
[Hormonal stimulation and in vitro cellular differentiation in the integument of the desert locust Schistocerca gregaria (author's transl)].
PubMed:
Influence of molt cycle and beta-ecdysone on protein synthesis in the chelicerate arthropod, Limulus polyphemus.
PubMed:
Production of specific-protein secretion granules by fat body cells of the blowfly, Calliphora erythrocephala. Substitution of an ovarian key factor by beta-ecdysone.
PubMed:
Protein synthesis in imaginal disks of Plodia interpunctella during development in vivo and in vitro.
PubMed:
Alterations in ecdysone content during the post-embryonic development of Chironomus thummi: correlations with chromosomal puffing.
PubMed:
Effects of two juvenile hormone analogs and beta-ecdysone on nymphal development, spermatogenesis, and embryogenesis in Dermacentor variabilis (Say) (Acari: Ixodidae).
PubMed:
Intercellular communication in insect development is hormonally controlled.
PubMed:
The mechanism of C-20 hydroxylation of alpha-ecdysone in the desert locust, Schistocerca gregaria.
PubMed:
In vitro activation of neurosecretory brain cells in Mamestra brassicae by beta-ecdysone.
PubMed:
Induction of acetylcholinesterase activity by beta-ecdysone in a Drosophila cell line.
PubMed:
Radiation-induced inhibition of eclosion in the tobacco hornworm, Manduca sexta.
PubMed:
The time during which beta-ecdysone is required for the differentiation in vitro and in situ of wing imaginal discs of Drosophila melanogaster.
PubMed:
Active ion transport and beta-acdysone induced differentiation of Drosophila melanogaster imaginal discs cultured in vitro.
PubMed:
The eversion and differentiation of Drosophila melanogaster leg and wing imaginal discs cultured in vitro with an optimal concentration of beta-ecdysone.
PubMed:
beta-ecdysone levels in pharate pupae of the stable fly, Stomoxys calcitrans and interaction with the chitin inhibitor diflubenzuron.
PubMed:
Juvenile hormone analogue counteracts growth stimulation and inhibition by ecdysones in clonal Drosophila cell line.
PubMed:
Small circular DNA in Drosophila melanogaster.
PubMed:
[Variations in the level of molting hormone during the second cycle of embryonic life in cockroaches].
PubMed:
[Comparison of the effects of alpha and beta ecdysone on a diploid clone of cultured Drosophila melanogaster cells in vitro: induction of proteins and morphological changes].
PubMed:
Selective activation of RNA polymerase I in fat body nuclei of Sarcophaga peregrina larvae by beta-ecdysone.
PubMed:
The in vitro synthesis and secretion of alpha-ecdysone by the ring glands of the fly, Sarcophaga bullata.
PubMed:
Hormonal control of growth and differentiation of insect tissues cultured in vitro.
PubMed:
Separation and detection of alpha- and beta-ecdysone using thin-layer chromatography.
PubMed:
Radioimmunoassay of arthropod moulting hormone:beta-ecdysone antibodies production and 125 I-iodinated tracer preparation.
PubMed:
Uptake of beta-ecdysone by the fat body and membrane vesicles of fat body cells of Sarcophaga peregrina larvae.
PubMed:
The initiation of adult development in Sarcophaga argyrostoma by beta-ecdysone.
PubMed:
Biosynthesis of alpha- and beta-ecdysone by the crayfish Orconectes limosus in vivo and by its Y-organs in vitro.
PubMed:
Effects of ecdysone and juvenile hormone on epidermal cell development in Hyalophora cecropia.
PubMed:
Effects of beta-ecdysone and juvenile hormone on the Na+/K+-dependent ATPase in imaginal disks of Drosophila melanogaster.
PubMed:
Biosynthesis of alpha-and beta-ecdysone in isolated abdomens of larvae of Musca domestica.
PubMed:
Alpha- and beta-ecdysone levels in insect haemolymph: correlation with developmental events.
PubMed:
Action of insect hormones at the cellular level. II. Differing sensitivity to beta-ecdysone of several lines and clones of Drosophila melanogaster cells.
PubMed:
The ovary as a source of alpha-ecdysone in an adult mosquito.
PubMed:
Effect of insect hormones on RNA polymerases of mass-isolated imaginal discs of Drosophila melanogaster cultured in vitro.
PubMed:
The effect of beta-ecdysone on Gromphadorhina adult female fat body in the transcriptional and translational levels.
PubMed:
beta-Ecdysone effects on the development of nucleopolyhedrosis in Heliothis spp.
PubMed:
Uptake and binding of beta-ecdysone in imaginal discs of Drosophila melanogaster.
PubMed:
RNA synthesis: a requirement for hormone-induced DNA amplification in Rhynchosciara americana.
PubMed:
RNA synthesis in imaginal disks of Galleria mellonella: effects of alpha- and beta- ecdysone and fat body in vitro.
PubMed:
[The effect of alpha- and beta-ecdysone on differentiation of imaginal disks of Drosophila melanogaster cultivated in vitro].
PubMed:
Influence of ecdysterone on the growth of cells and synthesis of macromolecules in established cell lines of Drosophila melanogaster.
PubMed:
The effect of beta-ecdysone on protein synthesis in imaginal discs of Drosophila melanogaster cultured in vitro.
PubMed:
The effect of beta-ecdysone on protein synthesis in imaginal discs of Drosophila melanogaster cultured in vitro.
PubMed:
Isolation of beta-ecdysone (20-hydroxyecdysone) from the parasitic nematode Ascaris lumbricoides.
PubMed:
Relative activities of alpha-ecdysone and beta-ecdysone for the differentiation in vitro of Drosophila melanogaster imaginal discs.
PubMed:
[Action of beta-ecdysone on the development of larval and imaginal epidermal cell lines, from the abdomen of permanent larva of Ceratitis capitata Wied (Dipt. Trypetidae)].
PubMed:
Antibodies to the insect moulting hormone beta-ecdysone.
PubMed:
Ecdysone-mediated stimulation of DOPA decarboxylase activity and its relationship to ovarian development in Aedes aegypti.
PubMed:
Interactions between beta-ecdysone and fat body during wing disk development in vitro.
PubMed:
The effects of eyestalk ablation and B-ecdysone on RNA synthesis in the androgenic glands of the protandric shrimp, Pandalus platyceros Brandt.
PubMed:
The Secretion of alpha-Ecdysone by the Prothoracic Glands of Manduca sexta In Vitro.
PubMed:
Galleria mellonella nerve cords in vitro: stage-specific survival and differential responsiveness to beta-ecdysone.
PubMed:
Circadian control of the cellular response to beta-ecdysone in Drosophila lebanonensis. I. Experimental puff induction and its relation to puparium formation.
PubMed:
Deposition of insect cuticle in vitro: differential responses to alpha- and beta-ecdysone.
PubMed:
Effects and interactions of juvenile hormone and beta-ecdysone on Drosophila imaginal discs cultured in vitro.
PubMed:
The apparent requirement of two hormones, alpha- and beta-ecdysone, for molting induction in insects.
PubMed:
Effects of alpha-ecdysone, beta-ecdysone and inokosterone on the in vitro evagination of Drosophila leg discs and the subsequent differentiation of imaginal integumentary structures.
PubMed:
The Activity of beta-Ecdysone in Four Gibberellin Bioassays.
PubMed:
Increased RNase H (hybridase) activity in the integument of blowfly larvae during development and under the influence of beta-ecdysone.
PubMed:
Binding proteins for an ecdysone metabolite in the crustacean hepatopancreas.
PubMed:
Inhibitory effects of alpha-amanitin on RNA synthesis and induction of DOPA-decarboxylase by beta-ecdysone.
PubMed:
Cellular Response to Ecdysterone in vitro.
PubMed:
Conversion of alpha ecdysone to beta ecdysone by crustaceans and insects.
PubMed:
[Structure of beta-ecdysone (1)].