lucigenin
10,10'-dimethyl-9,9'-biacridinium nitrate
Identification
| Name | lucigenin |
| IUPAC | 10-methyl-9-(10-methylacridin-10-ium-9-yl)acridin-10-ium;dinitrate |
| CAS Number | 2315-97-1 |
| EINECS | 219-023-4 |
| FDA UNII | Search |
| Molecular Formula | C28 H22 N4 O6 |
| Molecular Weight | 510.50654000 |
| MDL Number | MFCD00011925 |
| Beilstein | 3901768 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Flash Point | 32.00 °F. TCC ( 0.00 °C. ) (est) |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | information only not used for fragrances or flavors |
| Recommendation for lucigenin usage levels up to | not for fragrance use. |
| Recommendation for lucigenin flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
10,10'-
dimethyl-9,9'-biacridinium
10,10'-
dimethyl-9,9'-biacridinium nitrate
lucigenin nitrate
bis-N-
methyl acridinium nitrate
10-
methyl-9-(10-methylacridin-10-ium-9-yl)acridin-10-ium;dinitrate
PubMed:
In vitro modulation of oxidative burst via release of reactive oxygen species from immune cells by extracts of selected tropical medicinal herbs and food plants.
PubMed:
New analytical method for investigating the antioxidant power of food extracts on the basis of their electron-donating ability: comparison to the ferric reducing/antioxidant power (FRAP) assay.
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Uptake and protective effects of ergothioneine in human endothelial cells.
PubMed:
Detection of oxygen activation and determination of the activity of antioxidants towards reactive oxygen species by use of the chemiluminigenic probes luminol and lucigenin.
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Impact of α-lipoic acid on liver peroxisome proliferator-activated receptor-α, vascular remodeling, and oxidative stress in insulin-resistant rats.
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[The chemiluminescence of the polymorphonuclear leukocytes in food poisoning].
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Effects of aging and every-other-day feeding on the levels of oxygen radicals in rat brain slices.
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Modulation of human neutrophil oxidative metabolism and degranulation by extract of Tamarindus indica L. fruit pulp.
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Generation of reactive oxygen species from the reaction of selenium compounds with thiols and mammary tumor cells.
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Different efficiency of various synthetic antioxidants towards NADPH induced chemiluminescence in rat liver microsomes.
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Novel high-throughput assay for antioxidant capacity against superoxide anion.
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Cytochrome P450 (P450) isoforms expression, P450 concentration, monooxygenase activities, reactive oxygen species formation, lipid peroxidation, and glutathione content in wild catch carp and tench liver--influence of a two weeks exposure to phenobarbital.
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Double edge redox-implications for the interaction between endogenous thiols and copper ions: In vitro studies.
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Possible role of avian uncoupling protein in down-regulating mitochondrial superoxide production in skeletal muscle of fasted chickens.
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Evidence that high-dose L-arginine may be inappropriate for use by diabetic patients as a prophylactic blocker of methylglyoxal glycation.
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Metabolism of benzoquinone by yeast cells and oxidative characteristics of corresponding hydroquinone: application to highly sensitive measurement of yeast cell density by using benzoquinone and a chemiluminescent probe.
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Daily grape juice consumption reduces oxidative DNA damage and plasma free radical levels in healthy Koreans.
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In utero infection with PRRS virus modulates cellular functions of blood monocytes and alveolar lung macrophages in piglets.
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Inhibition of selenite-catalyzed superoxide generation and formation of elemental selenium (Se(o)) by copper, zinc, and aurintricarboxylic acid (ATA).