lucigenin

10,10'-dimethyl-9,9'-biacridinium nitrate

CAS: 2315-97-1 C28 H22 N4 O6 MW: 510.50654000

Identification

Namelucigenin
IUPAC10-methyl-9-(10-methylacridin-10-ium-9-yl)acridin-10-ium;dinitrate
CAS Number2315-97-1
EINECS219-023-4
FDA UNIISearch
Molecular FormulaC28 H22 N4 O6
Molecular Weight510.50654000
MDL NumberMFCD00011925
Beilstein3901768

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Flash Point 32.00 °F. TCC ( 0.00 °C. ) (est)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryinformation only not used for fragrances or flavors
Recommendation for lucigenin usage levels up tonot for fragrance use.
Recommendation for lucigenin flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

10,10'- dimethyl-9,9'-biacridinium 10,10'- dimethyl-9,9'-biacridinium nitrate lucigenin nitrate bis-N- methyl acridinium nitrate 10- methyl-9-(10-methylacridin-10-ium-9-yl)acridin-10-ium;dinitrate PubMed: In vitro modulation of oxidative burst via release of reactive oxygen species from immune cells by extracts of selected tropical medicinal herbs and food plants. PubMed: New analytical method for investigating the antioxidant power of food extracts on the basis of their electron-donating ability: comparison to the ferric reducing/antioxidant power (FRAP) assay. PubMed: Uptake and protective effects of ergothioneine in human endothelial cells. PubMed: Detection of oxygen activation and determination of the activity of antioxidants towards reactive oxygen species by use of the chemiluminigenic probes luminol and lucigenin. PubMed: Homocysteine induces the expression of C-reactive protein via NMDAr-ROS-MAPK-NF-κB signal pathway in rat vascular smooth muscle cells. PubMed: External mitochondrial NADH-dependent reductase of redox cyclers: VDAC1 or Cyb5R3? PubMed: Improved superoxide-generating system suitable for the assessment of the superoxide-scavenging ability of aqueous extracts of food constituents using ultraweak chemiluminescence. PubMed: Evaluation of the antioxidant activity of passion fruit (Passiflora edulis and Passiflora alata) extracts on stimulated neutrophils and myeloperoxidase activity assays. PubMed: 4-methylcoumarin derivatives inhibit human neutrophil oxidative metabolism and elastase activity. PubMed: Impact of α-lipoic acid on liver peroxisome proliferator-activated receptor-α, vascular remodeling, and oxidative stress in insulin-resistant rats. PubMed: [The chemiluminescence of the polymorphonuclear leukocytes in food poisoning]. PubMed: Effects of aging and every-other-day feeding on the levels of oxygen radicals in rat brain slices. PubMed: Modulation of human neutrophil oxidative metabolism and degranulation by extract of Tamarindus indica L. fruit pulp. PubMed: Generation of reactive oxygen species from the reaction of selenium compounds with thiols and mammary tumor cells. PubMed: Different efficiency of various synthetic antioxidants towards NADPH induced chemiluminescence in rat liver microsomes. PubMed: Novel high-throughput assay for antioxidant capacity against superoxide anion. PubMed: Cytochrome P450 (P450) isoforms expression, P450 concentration, monooxygenase activities, reactive oxygen species formation, lipid peroxidation, and glutathione content in wild catch carp and tench liver--influence of a two weeks exposure to phenobarbital. PubMed: Double edge redox-implications for the interaction between endogenous thiols and copper ions: In vitro studies. PubMed: Possible role of avian uncoupling protein in down-regulating mitochondrial superoxide production in skeletal muscle of fasted chickens. PubMed: Evidence that high-dose L-arginine may be inappropriate for use by diabetic patients as a prophylactic blocker of methylglyoxal glycation. PubMed: Metabolism of benzoquinone by yeast cells and oxidative characteristics of corresponding hydroquinone: application to highly sensitive measurement of yeast cell density by using benzoquinone and a chemiluminescent probe. PubMed: Daily grape juice consumption reduces oxidative DNA damage and plasma free radical levels in healthy Koreans. PubMed: In utero infection with PRRS virus modulates cellular functions of blood monocytes and alveolar lung macrophages in piglets. PubMed: Inhibition of selenite-catalyzed superoxide generation and formation of elemental selenium (Se(o)) by copper, zinc, and aurintricarboxylic acid (ATA).