Identification

Nameboric acid
IUPACboric acid
CAS Number10043-35-3
EINECS233-139-2
FDA UNIIR57ZHV85D4
Molecular FormulaB H3 O3
Molecular Weight61.83251000
MDL NumberMFCD00011337
Nikkaji NumberJ43.588K
Beilstein1697939

Regulatory

FDA/DG SANTE Petitions, Reviews, NoticesEU SANCO
DG SANTE Food Additivesboric acid
DG SANTE Food Contact Materialsboric acid
FDA Mainterm (SATF)10043-35-3 ; BORIC ACID
FDA RegulationFDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS

Physical Properties

Appearance white powder (est)
Assay 98.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 1.43500 @ 25.00 °C.
Flash Point 32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w) -0.610 (est)
Soluble in water, 2.117e+005 mg/L @ 25 °C (est)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesantimicrobial agents

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityoral-rat LD50 2660 mg/kg
Dermal Toxicitysubcutaneous-rat LD50 1400 mg/kg
Inhalation Toxicityinhalation-rat LCLo 28 mg/m3/4H

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorysubstances for use only as components of adhesives for food packaging, transporting, or holding food
Recommendation for boric acid usage levels up tonot for fragrance use.
Recommendation for boric acid flavor usage levels up tonot for flavor use.

ECSA Chemicals

Human Chemistry

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Glentham Life Sciences Ltd

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Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK.

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OQEMA

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Penta International Corporation

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Potential Uses

antimicrobial agents oral care agents

Natural Occurrence

not found in nature

Synonyms

basilit b boracic acid ortho boric acid boricacid borofax boron trihydroxide dr.'s 1 flea terminator DF dr.'s 1 flea terminator DFPBO dr.'s 1 flea terminator DT dr.'s 1 flea terminator DTPBO flea prufe super flea eliminator three elephant trihydroxyborone PubMed: A study on chemical composition and detection of chemical adulteration in tetra pack milk samples commercially available in Multan. PubMed: Aquaglyceroporins: generalized metalloid channels. PubMed: Doehlert design-desirability function multi-criteria optimal separation of 17 phenolic compounds from extra-virgin olive oil by capillary zone electrophoresis. PubMed: Homoarginine, β-ODAP, and asparagine contents of grass pea landraces cultivated in Turkey. PubMed: Asymmetrical behavioral response towards two boron toxicants depends on the ant species (Hymenoptera: Formicidae). PubMed: Impact of platinum on the soil invertebrate Folsomia candida. PubMed: Cellular responses in the Malpighian tubules of Scaptotrigona postica (Latreille, 1807) exposed to low doses of fipronil and boric acid. PubMed: Effect of different GRAS compounds in the control of apples blue mould. PubMed: [Determination of sixteen food additives in beverage by capillary zone electrophoresis]. PubMed: Spectrofluorimetric determination of ellagic acid in brandy. PubMed: Efficacy of commercial baits and new active ingredients against firebrats and silverfish (Zygentoma: Lepismatidae). PubMed: Influence of toxic bait type and starvation on worker and queen mortality in laboratory colonies of Argentine ant (Hymenoptera: Formicidae). PubMed: Field enhancement sample stacking for analysis of organic acids in traditional Chinese medicine by capillary electrophoresis. PubMed: Rapid and sensitive determination of sulfonamide residues in milk and chicken muscle by microfluidic chip electrophoresis. PubMed: An optical test strip for the detection of benzoic acid in food. PubMed: Microchip electrophoresis of bacteria using lipid-based liquid crystalline nanoparticles. PubMed: Insecticidal and repellent effects of tea tree (Melaleuca alternifolia) oil against Lucilia cuprina. PubMed: Reproductive toxicity parameters and biological monitoring in occupationally and environmentally boron-exposed persons in Bandirma, Turkey. PubMed: Analytical methods for SiO2 and other inorganic oxides in titanium dioxide or certain silicates for food additive specifications. PubMed: Phosphate additives determination in meat products by 31-phosphorus nuclear magnetic resonance using new internal reference standard: hexamethylphosphoroamide. PubMed: Identification of causative agents and species in shrimp implicated in a food poisoning case in Taiwan. PubMed: Use of multivariate statistical techniques to optimize the simultaneous separation of 13 phenolic compounds from extra-virgin olive oil by capillary electrophoresis. PubMed: The effects of some boron compounds against heavy metal toxicity in human blood. PubMed: [Determination of four amino acids in tea by capillary zone electrophoresis and direct ultraviolet detection without derivatization]. PubMed: Candidiasis (vulvovaginal). PubMed: Chronic boron exposure and human semen parameters. PubMed: Stability and reproducibility of a single-sample urinary C-peptide/creatinine ratio and its correlation with 24-h urinary C-peptide. PubMed: Determination of total lead in lipstick: development and validation of a microwave-assisted digestion, inductively coupled plasma-mass spectrometric method. PubMed: Receptor activated Ca(2+) release is inhibited by boric acid in prostate cancer cells. PubMed: Morphological alterations induced by boric acid and fipronil in the midgut of worker honeybee (Apis mellifera L.) larvae : Morphological alterations in the midgut of A. mellifera. PubMed: The effects of boric acid on sister chromatid exchanges and chromosome aberrations in cultured human lymphocytes. PubMed: Risk assessment of boron in glass wool insulation. PubMed: Sensitive determination of biogenic amines by capillary electrophoresis with a new fluorogenic reagent 3-(4-fluorobenzoyl)-2-quinolinecarboxaldehyde. PubMed: Plants tolerant of high boron levels. PubMed: Relative attractiveness of baits to Paratrechina longicornis (Hymenoptera: Formicidae). PubMed: Candidiasis (vulvovaginal). PubMed: Genotoxicity of five food preservatives tested on root tips of Allium cepa L. PubMed: Sensitive determination of carbohydrates labelled with p-nitroaniline by capillary electrophoresis with photometric detection using a 406 nm light-emitting diode. PubMed: Boron and the kidney. PubMed: [Scientific research related to food additives and acrylamide]. PubMed: Effects of single and repeated exposure to biocidal active substances on the barrier function of the skin in vitro. PubMed: Effects of hyperthermia and boric acid on skeletal development in rat embryos. PubMed: Educational intervention to control cockroach allergen exposure in the homes of hispanic children in Los Angeles: results of the La Casa study. PubMed: Enzymatic determination of urea in milk by sequential injection with spectrophotometric and conductometric detection. PubMed: Regulation system for protease production in Vibrio vulnificus. PubMed: Water solutions of boric acid and sugar for management of German cockroach populations in livestock production systems. PubMed: Influence of the extracting solvent upon the structural properties of Amaranth (Amaranthus hypochondriacus) glutelin. PubMed: Improving extraction of fumonisin mycotoxins from Brazilian corn-based infant foods. PubMed: Dietary boron supplementation enhances the effects of estrogen on bone mineral balance in ovariectomized rats. PubMed: Comparisons of toxic baits for controlling the cockroach, Blattella germanica: attractiveness and feeding stimulation. PubMed: A method for determining fumonisin B1 in corn using immunoaffinity column clean-up and thin layer chromatography/densitometry. PubMed: Optimization of the separation of phenolic compounds by micellar electrokinetic capillary chromatography. PubMed: Sol-gel composite films with controlled release of biocides. PubMed: Determination of borates in caviare by ion-exclusion chromatography. PubMed: Boron exposure from consumer products. PubMed: Individual and combined genotoxic response of boric acid and aflatoxin B1 in Escherichia coli PQ37. PubMed: An assessment of boric acid and borax using the IEHR Evaluative Process for Assessing Human Developmental and Reproductive Toxicity of Agents. Expert Scientific Committee. PubMed: The developmental toxicity of boric acid in rabbits. PubMed: Developmental toxicity NOAEL and postnatal recovery in rats fed boric acid during gestation. PubMed: Noncancer risk assessment: reproductive toxicology. PubMed: [Disinfection of wood in mushroom growing cellars with Mycetox]. PubMed: Toxicity and carcinogenicity studies of boric acid in male and female B6C3F1 mice. PubMed: The developmental toxicity of boric acid in mice, rats, and rabbits. PubMed: Perak, Malaysia, mass poisoning. Tale of the Nine Emperor Gods and rat tail noodles. PubMed: An outbreak of a food-related illness resembling boric acid poisoning. PubMed: A rapid, sensitive thin layer chromatography procedure for the detection of fumonisin B1 and B2. PubMed: Developmental toxicity of boric acid in mice and rats. PubMed: Aflatoxin in betel nut and its control by use of food preservatives. PubMed: An outbreak of aflatoxicosis and boric acid poisoning in Malaysia: a clinicopathological study. PubMed: Interactive effects of boron, selenium, and dietary protein on survival, growth, and physiology in mallard ducklings. PubMed: Normal boron excretion levels and borates related gastroenteritis cases in Singapore. PubMed: Quantitative aspects of two methods to dissolve collagen-free muscle proteins from acetone dry powders of Guelders ring sausage. PubMed: [Quantitative determination of the protein content of milk by ultraviolet spectrophotometry. 3. Determination of proteins in preserved milk samples]. PubMed: Boric acid toxicity. PubMed: A boric acid-rodenticide mixture used in the control of coexisting rodent-cockroach infestations. PubMed: Gastro-intestinal absorption and in vitro release of boric acid from water-emulsifying ointments. PubMed: Unaffected blood boron levels in newborn infants treated with a boric acid ointment. PubMed: Absorption of boric acid through human skin depending on the type of vehicle. PubMed: Colorimetric determination of boric acid in prawns, shrimp, and salted jelly fish by chelate extraction with 2-ethyl-1,3-hexanediol. PubMed: [Determination of boric acid (H3BO3) in shellfish and various foods]. PubMed: [Thin-layer chromatography of sugars (author's transl)]. PubMed: Collaborative study of the determination of boric acid in foods by atomic absorption spectrophotometry. PubMed: TOXICITY OF BORIC ACID THROUGH SKIN AND MUCOUS MEMBRANES. PubMed: BORIC ACID AND BABY POWDERS. PubMed: [Priority of public health or of contaminated butter? The resolution issued in 1940 on boric acid remains without effect]. PubMed: A buffered boric acid lactose medium for enrichment and presumptive identification of Escherichia coli. PubMed: A PRELIMINARY NOTE ON A NEW ASPECT OF THE EFFECTS OF BORIC ACID AS A FOOD PRESERVATIVE.