bromochloromethane

methylene bromochloride

CAS: 74-97-5 C H2 Br Cl MW: 129.38294000

Identification

Namebromochloromethane
IUPACbromo(chloro)methane
CAS Number74-97-5
EINECS200-826-3
FDA UNII45WX84110G
Molecular FormulaC H2 Br Cl
Molecular Weight129.38294000
MDL NumberMFCD00000880
Nikkaji NumberJ2.384A
Beilstein1730801

Regulatory

Physical Properties

Appearance colorless clear liquid (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 1.99100 @ 25.00 °C.
Boiling Point 68.00 °C. @ 760.00 mm Hg
Vapor Pressure 143.000000 mmHg @ 25.00 °C. (est)
Flash Point -9.00 °F. TCC ( -22.90 °C. ) (est)
logP (o/w) 1.410
Soluble in water, 1.67E+04 mg/L @ 25 °C (exp)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityoral-mouse LD50 4300 mg/kg
Dermal Toxicityskin-rabbit LD50 > 20000 mg/kg
Inhalation Toxicityinhalation-mouse LC50 12030 mg/m3/7H

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements', 'BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)\nBEHAVIORAL: GENERAL ANESTHETIC\nBEHAVIORAL: TREMOR']

Safety in Use

Categorypharmaceuticals / chemical synthisis
Recommendation for bromochloromethane usage levels up tonot for fragrance use.
Recommendation for bromochloromethane flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

bromo(chloro)methane mono bromomonochloromethane chloromethyl bromide fluorocarbon 1011 methane, bromochloro- methylene bromochloride PubMed: [Influences of high-fat diet and methanogens inhibitor on the cecal microbiota and fat metabolism in C57BL/6J mice]. PubMed: An antimethanogenic nutritional intervention in early life of ruminants modifies ruminal colonization by Archaea. PubMed: Improving pulsed radiofrequency glow discharge for time-of-flight mass spectrometry simultaneous elemental and molecular analysis. PubMed: In vitro-in vivo study on the effects of plant compounds on rumen fermentation, microbial abundances and methane emissions in goats. PubMed: Nutritional intervention in early life to manipulate rumen microbial colonization and methane output by kid goats postweaning. PubMed: Effect of bromochloromethane and fumarate on phylogenetic diversity of the formyltetrahydrofolate synthetase gene in bovine rumen. PubMed: Physiologically Based Pharmacokinetic (PBPK) Modeling of Metabolic Pathways of Bromochloromethane in Rats. PubMed: Effect of bromochloromethane on methane emission, rumen fermentation pattern, milk yield, and fatty acid profile in lactating dairy goats. PubMed: Responses in digestion, rumen fermentation and microbial populations to inhibition of methane formation by a halogenated methane analogue. PubMed: Tuneable microsecond-pulsed glow discharge design for the simultaneous acquisition of elemental and molecular chemical information using a time-of-flight mass spectrometer. PubMed: Inhibition of methanogens by bromochloromethane: effects on microbial communities and rumen fermentation using batch and continuous fermentations. PubMed: Synthesis of nanoscale carceplexes from deep-cavity cavitands. PubMed: Isobaric and isochoric freezing of CH2BrCl and isostructural relations between CH2Cl2, CH2Br2 and CH2BrCl. PubMed: Quantitation and diversity analysis of ruminal methanogenic populations in response to the antimethanogenic compound bromochloromethane. PubMed: Combined vacuum ultraviolet laser and synchrotron pulsed field ionization study of CH2BrCl. PubMed: On the location of conical intersections in CH2BrCl using MS-CASPT2 methods. PubMed: Metabolism of mono- and dihalogenated C1 and C2 compounds by Xanthobacter autotrophicus growing on 1,2-dichloroethane. PubMed: Reduction of greenhouse gases from anaerobic piggery wastewater treatment by bromochloromethane in Taiwan. PubMed: Comparative mutagenicity of halomethanes and halonitromethanes in Salmonella TA100: structure-activity analysis and mutation spectra. PubMed: Detection limits for time-resolved coherent two-dimensional vibrational spectroscopy. PubMed: Correlations of Henry's Law Gas-Solid Virial Coefficients and Chromatographic Retention Times for Hydrocarbons and Halocarbons Adsorbed on Carbopack C Carbon. PubMed: Predicting vehicle effects on the dermal absorption of halogenated methanes using physiologically based modeling. PubMed: Physiologically based modeling of nonsteady state dermal absorption of halogenated methanes from an aqueous solution. PubMed: Preparation of Aminoalkyl Chlorohydrin Hydrochlorides: Key Building Blocks for Hydroxyethylamine-Based HIV Protease Inhibitors. PubMed: Expression of mammalian glutathione S-transferase 5-5 in Salmonella typhimurium TA1535 leads to base-pair mutations upon exposure to dihalomethanes. PubMed: Quantitative structure-activity relationship models correctly predict the toxic and aneuploidizing properties of six halogenated methanes in Aspergillus nidulans. PubMed: Effect of isoniazid or phenobarbital pretreatment on the metabolism of dihalomethanes to carbon monoxide. PubMed: Dermal absorption of neat and aqueous volatile organic chemicals in the Fischer 344 rat. PubMed: Physiologically based pharmacokinetic modeling with dichloromethane, its metabolite, carbon monoxide, and blood carboxyhemoglobin in rats and humans. PubMed: Determining kinetic constants of chlorinated ethane metabolism in the rat from rates of exhalation. PubMed: Damage to protein synthesis concurrent with lipid peroxidation in rat liver slices: effect of halogenated compounds, peroxides, and vitamin E1. PubMed: Synthesis and oral antifungal activity of novel azolylpropanolones and related compounds. PubMed: Halogenated compounds as inducers of lipid peroxidation in tissue slices. PubMed: A physiologically based simulation approach for determining metabolic constants from gas uptake data. PubMed: A physiological pharmacokinetic model for dermal absorption of vapors in the rat. PubMed: Dermal absorption of dihalomethane vapors. PubMed: Chemical reactivity and mutagenicity of some dihalomethanes. PubMed: The inhalation toxicity of pyrolysis products of bromochloromethane (CH2BrCl) and bromotrifluoromethane (CBrF3). PubMed: Some solvent effects on the solvent extraction of 8-quinolinol. PubMed: The toxicity of bromochloromethane (methylene chlorobromide) as determined on laboratory animals.