cantharidin
(3aa,4b,7b,7aa)-hexahydro-3a,7a-dimethyl-4,7-epoxyisobenzofuran-1,3-dione
Identification
| Name | cantharidin |
| CAS Number | 56-25-7 |
| EINECS | 200-263-3 |
| FDA UNII | IGL471WQ8P |
| Molecular Formula | C10 H12 O4 |
| Molecular Weight | 196.20244000 |
| MDL Number | MFCD00134968 |
| Nikkaji Number | J1.376E |
| Beilstein | 0085302 |
Regulatory
Physical Properties
| Appearance | brown to black powder (est) |
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 218.00 °C. @ 760.00 mm Hg |
| Boiling Point | 326.87 °C. @ 760.00 mm Hg (est) |
| Flash Point | 295.00 °F. TCC ( 146.10 °C. ) (est) |
| logP (o/w) | -0.409 (est) |
| Soluble in | water, 4138 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | oral-cat LDLo 310 mg/kg |
| Dermal Toxicity | subcutaneous-chicken LDLo 75 mg/kg |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for cantharidin usage levels up to | not for fragrance use. |
| Recommendation for cantharidin flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
cantharides camphor
cantharidine
cantharone
(1R,2S,3R,6S)-1,2-
dimethyl-3,6-epoxycyclohexane-1,2-dicarboxylic anhydride
(1S,3S,4R,7R)-2,6-
dimethyl-4,10-dioxa-tricyclo[5.2.1.0-2,6]decane-3,5-dione
(1R,2S,6R,7S)-2,6-
dimethyl-4,10-dioxa-tricyclo[5.2.1.0*2,6*]decane-3,5-dione
(1R,7S)-2,6-
dimethyl-4,10-dioxa-tricyclo[5.2.1.0*2,6*]decane-3,5-dione
(1S,2R,6S,7R)-2,6-
dimethyl-4,10-dioxa-tricyclo[5.2.1.0*2,6*]decane-3,5-dione
(2S,7S,1R,6R)-2,6-
dimethyl-4,10-dioxatricyclo[5.2.1.0<2,6>]decane-3,5-dione
(3aR,4S,7R,7aS)-3a,7a-
dimethylhexahydro-4,7-epoxy-2-benzofuran-1,3-dione
4,7-
epoxyisobenzofuran-1,3-dione, hexahydro-3a,7a-dimethyl-, (3aR,4S,7R,7aS)-
4,7-
epoxyisobenzofuran-1,3-dione, hexahydro-3a,7a-dimethyl-, (3aR,4S,7R,7aS)-rel-
(3aa,4b,7b,7aa)-
hexahydro-3a,7a-dimethyl-4,7-epoxyisobenzofuran-1,3-dione
kantaridin
kantharidin
Info:
Cantharidin
PubMed:
Identification of multiple small heat-shock protein genes in Plutella xylostella (L.) and their expression profiles in response to abiotic stresses.
PubMed:
Recent advances in developing insect natural products as potential modern day medicines.
PubMed:
Safety of cantharidin: a retrospective review of cantharidin treatment in 405 children with molluscum contagiosum.
PubMed:
Liposome encapsulation reduces cantharidin toxicity.
PubMed:
Type 2A phosphoprotein phosphatase is required for asexual development and pathogenesis of Sclerotinia sclerotiorum.
PubMed:
Role of Rho-kinase in guinea-pig gallbladder smooth muscle contraction.
PubMed:
Flavonoids as aryl hydrocarbon receptor agonists/antagonists: effects of structure and cell context.
PubMed:
Cantharidin revisited: a blistering defense of an ancient medicine.
PubMed:
Protein phosphatase 2A is involved in hyphal growth of Neurospora crassa.
PubMed:
Cantharidin toxicosis in horses.