cantharidin

(3aa,4b,7b,7aa)-hexahydro-3a,7a-dimethyl-4,7-epoxyisobenzofuran-1,3-dione

CAS: 56-25-7 C10 H12 O4 MW: 196.20244000

Identification

Namecantharidin
CAS Number56-25-7
EINECS200-263-3
FDA UNIIIGL471WQ8P
Molecular FormulaC10 H12 O4
Molecular Weight196.20244000
MDL NumberMFCD00134968
Nikkaji NumberJ1.376E
Beilstein0085302

Regulatory

Physical Properties

Appearance brown to black powder (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 218.00 °C. @ 760.00 mm Hg
Boiling Point 326.87 °C. @ 760.00 mm Hg (est)
Flash Point 295.00 °F. TCC ( 146.10 °C. ) (est)
logP (o/w) -0.409 (est)
Soluble in water, 4138 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityoral-cat LDLo 310 mg/kg
Dermal Toxicitysubcutaneous-chicken LDLo 75 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for cantharidin usage levels up tonot for fragrance use.
Recommendation for cantharidin flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

found in nature

Synonyms

cantharides camphor cantharidine cantharone (1R,2S,3R,6S)-1,2- dimethyl-3,6-epoxycyclohexane-1,2-dicarboxylic anhydride (1S,3S,4R,7R)-2,6- dimethyl-4,10-dioxa-tricyclo[5.2.1.0-2,6]decane-3,5-dione (1R,2S,6R,7S)-2,6- dimethyl-4,10-dioxa-tricyclo[5.2.1.0*2,6*]decane-3,5-dione (1R,7S)-2,6- dimethyl-4,10-dioxa-tricyclo[5.2.1.0*2,6*]decane-3,5-dione (1S,2R,6S,7R)-2,6- dimethyl-4,10-dioxa-tricyclo[5.2.1.0*2,6*]decane-3,5-dione (2S,7S,1R,6R)-2,6- dimethyl-4,10-dioxatricyclo[5.2.1.0<2,6>]decane-3,5-dione (3aR,4S,7R,7aS)-3a,7a- dimethylhexahydro-4,7-epoxy-2-benzofuran-1,3-dione 4,7- epoxyisobenzofuran-1,3-dione, hexahydro-3a,7a-dimethyl-, (3aR,4S,7R,7aS)- 4,7- epoxyisobenzofuran-1,3-dione, hexahydro-3a,7a-dimethyl-, (3aR,4S,7R,7aS)-rel- (3aa,4b,7b,7aa)- hexahydro-3a,7a-dimethyl-4,7-epoxyisobenzofuran-1,3-dione kantaridin kantharidin Info: Cantharidin PubMed: Identification of multiple small heat-shock protein genes in Plutella xylostella (L.) and their expression profiles in response to abiotic stresses. PubMed: Recent advances in developing insect natural products as potential modern day medicines. PubMed: Safety of cantharidin: a retrospective review of cantharidin treatment in 405 children with molluscum contagiosum. PubMed: Liposome encapsulation reduces cantharidin toxicity. PubMed: Type 2A phosphoprotein phosphatase is required for asexual development and pathogenesis of Sclerotinia sclerotiorum. PubMed: Role of Rho-kinase in guinea-pig gallbladder smooth muscle contraction. PubMed: Flavonoids as aryl hydrocarbon receptor agonists/antagonists: effects of structure and cell context. PubMed: Cantharidin revisited: a blistering defense of an ancient medicine. PubMed: Protein phosphatase 2A is involved in hyphal growth of Neurospora crassa. PubMed: Cantharidin toxicosis in horses.