chloroacetone

1-chloro-2-propanone

CAS: 78-95-5 C3 H5 Cl O MW: 92.52405000

Identification

Namechloroacetone
IUPAC1-chloropropan-2-one
CAS Number78-95-5
EINECS201-161-1
FDA UNII60ZTR74268
Molecular FormulaC3 H5 Cl O
Molecular Weight92.52405000
MDL NumberMFCD00000936
Nikkaji NumberJ1.487G
Beilstein605369

Regulatory

Physical Properties

Appearance colorless to pale yellow clear liquid (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 1.16200 @ 25.00 °C.
Melting Point -44.50 °C. @ 760.00 mm Hg
Boiling Point 119.00 °C. @ 760.00 mm Hg
Vapor Pressure 15.517000 mmHg @ 25.00 °C. (est)
Flash Point 82.00 °F. TCC ( 27.78 °C. )
logP (o/w) -0.282 (est)
Soluble in water, 9.00E+04 mg/L @ 20 °C (exp)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityintraperitoneal-mouse LD50 92 mg/kg
Dermal Toxicityskin-guinea pig LD50 100 uL/kg
Inhalation Toxicityinhalation-human LCLo 605 ppm/10M

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements', 'BEHAVIORAL: TREMOR\nBEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)\nBEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD', 'BEHAVIORAL: TREMOR\nBEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)\nBEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD']

Safety in Use

Categorypharmaceuticals / chemical synthisis
Recommendation for chloroacetone usage levels up tonot for fragrance use.
Recommendation for chloroacetone flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

chloracetone 1- chloro-2-ketopropane 1- chloro-2-oxopropane 1- chloro-2-propanone 3- chloro-2-propanone 1- chloroacetone 1- chloropropan-2-one 1- chloropropanone MCA methyl chloromethyl ketone 2- propanone, 1-chloro- tonite PubMed: Synthesis and antimicrobial evaluation of amide derivatives of benzodifuran-2-carboxylic acid. PubMed: Products and mechanism of the reactions of OH radicals and Cl atoms with methyl methacrylate (CH2═C(CH3)C(O)OCH3) in the presence of NOx. PubMed: Investigations of chemical warfare agents and toxic industrial compounds with proton-transfer-reaction mass spectrometry for a real-time threat monitoring scenario. PubMed: Multi-component one-pot synthesis and antimicrobial activities of 3-methyl-1,4-diphenyl-7-thioxo-4,6,8,9-tetrahydro-pyrazolo[5,4-b]pyrimidino[5,4-e]pyridine-5-one and related derivatives. PubMed: The identification of chlorinated acetones in analyses of aged triacetone triperoxide (TATP). 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