citric acid monohydrate

1,2,3-propanetricarboxylic acid, 2-hydroxy-, monohydrate

CAS: 5949-29-1 C6 H10 O8 MW: 210.13930000

Identification

Namecitric acid monohydrate
IUPAC2-hydroxypropane-1,2,3-tricarboxylic acid;hydrate
CAS Number5949-29-1
FDA UNII2968PHW8QP
Molecular FormulaC6 H10 O8
Molecular Weight210.13930000

Regulatory

JECFA Food AdditiveCitric Acid
GSFA CodexCitric acid (330)
FDA Mainterm (SATF)77-92-9 ; CITRIC ACID
FDA RegulationFDA PART 131 -- MILK AND CREAM

Physical Properties

Appearance white powder (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 558.50 °C. @ 760.00 mm Hg (est)
Flash Point 557.00 °F. TCC ( 291.60 °C. ) (est)
Soluble in water, 1e+006 mg/L @ 25 °C (est)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesbuffering agents

No sensory data available

Safety Information

Oral/Parenteral Toxicityintraperitoneal-rat LD50 375 mg/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavoring agents, food additives
Recommendation for citric acid monohydrate usage levels up tonot for fragrance use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

citric acid hydrate citric acid, monohydrate 2- hydroxypropane-1,2,3-tricarboxylic acid hydrate 2- hydroxypropane-1,2,3-tricarboxylic acid, hydrate 2- hydroxypropane-1,2,3-tricarboxylic acid;hydrate 1,2,3- propane tricarboxylic acid 1,2,3- propanetricarboxylic acid, 2-hydroxy-, monohydrate PubMed: Effect of plasticiser type on the hot melt extrusion of venlafaxine hydrochloride. PubMed: [Effect of excipients on the preparation and properties of antibiotic solution for intravenous application]. PubMed: A comparative evaluation of fluoridated and non-fluoridated mouthrinses using a 5-day cycling enamel erosion model. PubMed: Influence of copigmentation on stability of anthocyanins from purple potato peel in both liquid state and solid state. PubMed: Properties of melt extruded enteric matrix pellets. PubMed: Critical evaluation of sequential leaching procedures for the determination of Ni and Mn species in welding fumes. PubMed: Reaction between drug substances and pharmaceutical excipients: formation of citric acid esters and amides of carvedilol in the solid state. PubMed: Citric acid monohydrate as a release-modifying agent in melt extruded matrix tablets. PubMed: Formation of interconnected macropores in apatitic calcium phosphate bone cement with the use of an effervescent additive. PubMed: Investigation of an effervescent additive as porogenic agent for bone cement macroporosity. PubMed: Synthesis and structure characterization of chromium oxide prepared by solid thermal decomposition reaction. PubMed: [Determination of trace cobalt in water samples by graphite furnace atomic absorption spectrometry after cloud point]. PubMed: Properties of hot-melt extruded tablet formulations for the colonic delivery of 5-aminosalicylic acid. PubMed: Experimental designed optimisation and stability evaluation of dry suspensions with artemisinin derivatives for paediatric use. PubMed: Pilot randomized double-blind trial of treatment of Mycobacterium ulcerans disease (Buruli ulcer) with topical nitrogen oxides. PubMed: Citric acid production by selected mutants of Aspergillus niger from cane molasses. PubMed: The utility of alizarin red s staining in calcium pyrophosphate dihydrate crystal deposition disease. PubMed: Development of a lyophilized parenteral pharmaceutical formulation of the investigational polypeptide marine anticancer agent kahalalide F. PubMed: An oral sodium citrate-citric acid non-particulate buffer in humans. PubMed: Comparative analysis of the nuclear proliferative index (Ki-67) in benign prostate, prostatic intraepithelial neoplasia, and prostatic carcinoma. PubMed: A sensitive bioassay for teicoplanin in serum in the presence or absence of other antibiotics. PubMed: Lipid deficient extender for bovine spermatozoa: its development and use in measuring freezing-induced lipid loss. PubMed: [Studies On Phosphatase Activity In Some Parasitic Helminths]