cytochalasin D

lygosporin A

CAS: 22144-77-0 C30 H37 N O6 MW: 507.62709000

Identification

Namecytochalasin D
CAS Number22144-77-0
EINECS244-804-1
FDA UNIISY9F0FZ3TO
Molecular FormulaC30 H37 N O6
Molecular Weight507.62709000
MDL NumberMFCD00077706
Beilstein1632828

Regulatory

Physical Properties

Appearance white fluffy powder (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 712.10 °C. @ 760.00 mm Hg (est)
Flash Point 724.00 °F. TCC ( 384.50 °C. ) (est)
logP (o/w) 2.640 (est)
Soluble in water, 0.8627 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityintraperitoneal-mouse LD50 2 mg/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements', 'PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE\nBEHAVIORAL: EXCITEMENT']

Safety in Use

Categorynatural substances and extractives

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Potential Uses

None Found

Natural Occurrence

found in nature

Synonyms

cytochalasind lygosporin A zygosporin A PubMed: Transport of Egg White ACE-Inhibitory Peptide, Gln-Ile-Gly-Leu-Phe, in Human Intestinal Caco-2 Cell Monolayers with Cytoprotective Effect. PubMed: Transport of IRW, an ovotransferrin-derived antihypertensive peptide, in human intestinal epithelial Caco-2 cells. PubMed: Transepithelial transport of theasinensins through Caco-2 cell monolayers and their absorption in Sprague-Dawley rats after oral administration. PubMed: [Relation analysis between intracellular distribution of nanomateriarls, ROS generation and DNA damage]. PubMed: Interactions between Clostridium perfringens spores and Raw 264.7 macrophages. PubMed: Internalization of Escherichia coli o157:h7 by bovine rectal epithelial cells. PubMed: Campylobacter fetus translocation across Caco-2 cell monolayers. PubMed: The Nf-actin gene is an important factor for food-cup formation and cytotoxicity of pathogenic Naegleria fowleri. PubMed: Cellular differentiation in moss protonemata: a morphological and experimental study. PubMed: A new model for hemoglobin ingestion and transport by the human malaria parasite Plasmodium falciparum. PubMed: Myosin light chain kinase inhibition: correction of increased intestinal epithelial permeability in vitro. PubMed: Actin is required for endocytic trafficking in the malaria parasite Plasmodium falciparum. PubMed: Fine particles that adsorb lipopolysaccharide via bridging calcium cations may mimic bacterial pathogenicity towards cells. PubMed: Specific effects of denaturation, hydrolysis and exposure to Lactococcus lactis on bovine beta-lactoglobulin transepithelial transport, antigenicity and allergenicity. PubMed: Adhesion and ingestion activities of fish phagocytes induced by bacterium Aeromonas salmonicida can be distinguished and directly measured from highly diluted whole blood of fish. PubMed: Campylobacter fetus adheres to and enters INT 407 cells. PubMed: MYO1, a novel, unconventional myosin gene affects endocytosis and macronuclear elongation in Tetrahymena thermophila. PubMed: Use of green fluorescent protein (GFP) to study the invasion pathways of Edwardsiella tarda in in vivo and in vitro fish models. PubMed: A semiautomated fluorescence-based cell-to-cell fusion assay for gp120-gp41 and CD4 expressing cells. PubMed: Effect of capsianoside, a diterpene glycoside, on tight-junctional permeability. PubMed: [An inhibitory analysis of the role of the enterocyte cytoskeleton in the absorption of food substances in the small intestine]. PubMed: Down-regulation of surface FcRI and decrease in antibody-dependent cellular cytotoxicity of cultured monocytes. Reversal by monensin or cytochalasin-D. PubMed: Toxic fungal metabolites in food. PubMed: Teratogenicity of cytochalasin D in the mouse.