dextro-(+)-neopterin
neopterin D-erythro-form
Identification
| Name | dextro-(+)-neopterin |
| IUPAC | 2-amino-6-[(1S,2R)-1,2,3-trihydroxypropyl]-1H-pteridin-4-one |
| CAS Number | 2009-64-5 |
| EINECS | 217-924-7 |
| FDA UNII | 9PLD60N7SO |
| Molecular Formula | C9 H11 N5 O4 |
| Molecular Weight | 253.21847000 |
| MDL Number | MFCD00042801 |
| Nikkaji Number | J82.093H |
| Beilstein | 089070 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 1e+006 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for dextro-(+)-neopterin usage levels up to | not for fragrance use. |
| Recommendation for dextro-(+)-neopterin flavor usage levels up to | not for flavor use. |
BOC Sciences
Best of Chemicals Supplier
Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...
Potential Uses
Natural Occurrence
Synonyms
(S-(R*,S*))-2-
amino-6-(1,2,3-trihydroxypropyl)-1H-pteridin-4-one
2-
amino-6-[(1S,2R)-1,2,3-trihydroxypropyl]-1H-pteridin-4-one
6-(D-
erythro-1,2,3-Trihydroxypropyl)pterin
1,2,3-
proanetriol
D-(+)-neo
pterin
neo
pterin D-erythro-form
PubMed:
Capillary electrophoresis of pterin derivatives responsible for the warning coloration of Heteroptera.
PubMed:
Simultaneous detection of six urinary pteridines and creatinine by high-performance liquid chromatography-tandem mass spectrometry for clinical breast cancer detection.
PubMed:
Assignment of pterin deaminase activity to an enzyme of unknown function guided by homology modeling and docking.
PubMed:
Investigation of urinary pteridine levels as potential biomarkers for noninvasive diagnosis of cancer.
PubMed:
Optimization of urinary pteridine analysis conditions by CE-LIF for clinical use in early cancer detection.
PubMed:
An Fe2+-dependent cyclic phosphodiesterase catalyzes the hydrolysis of 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate in methanopterin biosynthesis.
PubMed:
Characterization of an Fe(2+)-dependent archaeal-specific GTP cyclohydrolase, MptA, from Methanocaldococcus jannaschii.
PubMed:
(6R)-5,6,7,8-tetrahydro-L-biopterin and its stereoisomer prevent ischemia reperfusion injury in human forearm.
PubMed:
Mechanism of dihydroneopterin aldolase. NMR, equilibrium and transient kinetic studies of the Staphylococcus aureus and Escherichia coli enzymes.
PubMed:
Suppression of ischemia-reperfusion injury in murine models by neopterins.
PubMed:
Analysis of 6R- and 6S-tetrahydrobiopterin and other pterins by reversed-phase ion-pair liquid-chromatography with fluorimetric detection by post-column sodium nitrite oxidation.
PubMed:
Analysis for fully oxidized neopterin in serum by high-performance liquid chromatography.
PubMed:
Synthesis of enzymatically active D-7,8-dihydroneopterin-3'-triphosphate.
PubMed:
Inhibition of GTP cyclohydrolase I by pterins.
PubMed:
Lethal mutations induced in Drosophila melanogaster by direct or indirect action of pteridines.
PubMed:
Neopterin retards loss of serotonin N-acetyltransferase activity from cultured chick pineal glands.
PubMed:
[Pterin chemistry. 43. Synthesis of D-neopterin-3'-phosphate and D-neopterin-2',3'-cyclophosphate. Considerations on the biogenesis of biopterin].