dextro-homoserine
butyric acid, 2-amino-4-hydroxy-, D- (8CI)
Identification
| Name | dextro-homoserine |
| IUPAC | (2R)-2-amino-4-hydroxybutanoic acid |
| CAS Number | 6027-21-0 |
| FDA UNII | 5VK5MQ3TVS |
| Molecular Formula | C4 H9 N O3 |
| Molecular Weight | 119.12033000 |
| MDL Number | MFCD00077786 |
| Nikkaji Number | J9.212F |
| Beilstein | 1721680 |
| XlogP3 | -4.40 (est) |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 368.72 °C. @ 760.00 mm Hg (est) |
| Flash Point | 350.00 °F. TCC ( 176.80 °C. ) (est) |
| logP (o/w) | -1.289 (est) |
| Soluble in | water, 2.931e+005 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | information only not used for fragrances or flavors |
| Recommendation for dextro-homoserine usage levels up to | not for fragrance use. |
| Recommendation for dextro-homoserine flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
(2R)-2-
amino-4-hydroxybutanoic acid
(R)-2-
amino-4-hydroxybutanoic acid
(R)-(+)-2-
amino-4-hydroxybutyric acid
butyric acid, 2-amino-4-hydroxy-, D- (8CI)
D-homo
serin
R-homo
serine
PubMed:
Mutations in the Arabidopsis homoserine kinase gene DMR1 confer enhanced resistance to F. culmorum and F. graminearum.
PubMed:
A Simple Enzymatic Method for Production of a Wide Variety of D-Amino Acids Using L-Amino Acid Oxidase from Rhodococcus sp. AIU Z-35-1.
PubMed:
Structure of the O-antigen of Acinetobacter lwoffii EK30A; identification of d-homoserine, a novel non-sugar component of bacterial polysaccharides.
PubMed:
Engineering d-amino acid containing novel protease inhibitors using catalytic site architecture.
PubMed:
Improved synthesis and the crystal structure of methyl 4,6-dideoxy-4-(3-deoxy-L-glycero-tetronamido)-alpha-D-mannopyrano side, the methyl alpha-glycoside of the intracatenary repeating unit of the O-polysaccharide of Vibrio cholerae O:1.
PubMed:
LD-carboxypeptidase activity in Escherichia coli. II. Isolation, purification and characterization of the enzyme from E. coli K 12.
PubMed:
A convenient resolution of (+/-)-homoserine to afford carbobenzoxy-D-homoserine and D-homoserine.