diethyl amine hydrochloride
ethanamine, N-ethyl-, hydrochloride (1:1)
Identification
| Name | diethyl amine hydrochloride |
| CAS Number | 660-68-4 |
| EINECS | 211-541-9 |
| FDA UNII | ZE9V3G1135 |
| Molecular Formula | C4 H12 Cl N |
| Molecular Weight | 109.59864000 |
| MDL Number | MFCD00012499 |
| Beilstein | 3590084 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 228.50 °C. @ 760.00 mm Hg |
| Boiling Point | 57.30 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure | 218.000000 mmHg @ 25.00 °C. (est) |
| Flash Point | 32.00 °F. TCC ( 0.00 °C. ) (est) |
| logP (o/w) | 0.632 (est) |
| Soluble in | water, 1.00E+06 mg/L @ 25 °C (exp) |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | oral-guinea pig LD50 9500 mg/kg |
| Dermal Toxicity | subcutaneous-mouse LD50 1130 mg/kg |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | pharmaceuticals / chemical synthisis |
| Recommendation for diethyl amine hydrochloride usage levels up to | not for fragrance use. |
| Recommendation for diethyl amine hydrochloride flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
diethylamine hydrochloride
diethylamine, chloride
diethylamine, hydrochloride
diethylaminehydrochloride
diethylammonium chloride
diethylazanium;chloride
ethanamine, N-ethyl-, hydrochloride (1:1)
ethylamine, N-ethyl-, hydrochloride
N-
ethylethanamine hydrochloride
N-
ethylethanaminium chloride
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Synthesis of novel 2-(substituted amino)alkylthiopyrimidin-4(3H)-ones as potential antimicrobial agents.
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Determination of butenafine hydrochloride in human plasma by liquid chromatography electrospray ionization-mass spectrometry following its topical administration in human subjects.
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Scalable synthesis of (1-cyclopropyl)cyclopropylamine hydrochloride.
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Formulation and evaluation of verapamil hydrochloride loaded solid lipid microparticles.
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Use of N, N-diethyl-p-phenylenediamine sulphate for the spectrophotometric determination of some phenolic and amine drugs.
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A 4-aminoquinoline derivative that markedly sensitizes tumor cell killing by Akt inhibitors with a minimum cytotoxicity to non-cancer cells.
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Biochemical manipulation via iron chelation to enhance porphyrin production from porphyrin precursors.
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NO-1886, a lipoprotein lipase activator, attenuates vascular smooth muscle contraction in rat aorta.
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Development and validation of a liquid chromatographic/tandem mass spectrometric method for the determination of sertraline in human plasma.
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Ropinirole hydrochloride, a dopamine agonist.
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Tableting of Eudragit RS and propranolol hydrochloride solid dispersion: effect of particle size, compaction force, and plasticizer addition on drug release.
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Aminated polysaccharide microspheres as DNA delivery systems.
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Spatial relationship between the prodan site, Trp-214, and Cys-34 residues in human serum albumin and loss of structure through incremental unfolding.
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Fluorescent labeling of drugs and simple organic compounds containing amine functional groups, utilizing dansyl chloride in Na(2)CO(3) buffer.
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Excitation of rat striatal large neurons by dopamine and/or glutamate released from nerve terminals via presynaptic nicotinic receptor (A4beta2 type) stimulation.
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Regulated workplace ketones and their interference in the PFBHA method for aldehydes.
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Application of first-derivative UV-spectrophotometry, TLC-densitometry and liquid chromatography for the simultaneous determination of mebeverine hydrochloride and sulpiride.
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Actions of adenosine A2A receptor antagonist KW-6002 on drug-induced catalepsy and hypokinesia caused by reserpine or MPTP.
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Electrophysiological characterization of BRL-32872 in canine Purkinje fiber and ventricular muscle. Effect on early after-depolarizations and repolarization dispersion.
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Role of edrophonium in prevention of the re-inhibition of acetylcholinesterase by phosphorylated oxime.
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Electromechanical effects of newly synthetized propafenone derivatives on isolated guinea-pig heart muscle preparations.
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Endothelin-1 and endothelin-3 modulate dopaminergic neurons through different mechanisms.
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Modification of pig kidney diamine oxidase with ethoxyformic anhydride and rose bengal: evidence for essential histidyl residue at the active site.
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Improved high-performance liquid chromatographic assay for the stereoselective determination of mexiletine in plasma.
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[High-performance liquid chromatographic determination of propanidid and etomidate].
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Tamoxifen inhibition of prolactin action in the mouse mammary gland.
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[Chemical constituents of the leaves of Crataegus pinnatifida Bge. var. major N. E. Br].
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High-performance liquid chromatographic determination of phenylpropanolamine in human plasma and urine, using column switching combined with ion-pair chromatography.
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Antiestrogen inhibition of prolactin-induced growth of the Nb2 rat lymphoma cell line.
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Antiulcerogenic and antisecretory effects of a novel diphenylmethane derivative and antiestrogen binding site ligand.
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High-performance liquid chromatographic assay for dilevalol in human plasma and urine using a PRP-1 column and fluorimetric detection.
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Histamine and growth: interaction of antiestrogen binding site ligands with a novel histamine site that may be associated with calcium channels.
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Prostaglandin production by the guinea-pig endometrium: is calcium necessary?
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[Hemodynamic effects of intravenously administered celiprolol in patient with coronary heart disease and depressed left ventricular function].
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Psychopharmacology of midalcipran, 1-phenyl-1-diethyl-amino-carbonyl-2-aminomethylcyclopropane hydrochloride (F 2207), a new potential antidepressant.
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Biochemical profile of midalcipran (F 2207), 1-phenyl-1-diethyl-aminocarbonyl-2-aminomethyl-cyclopropane (Z) hydrochloride, a potential fourth generation antidepressant drug.
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Simultaneous determination of oxprenolol and 2H6-labelled oxprenolol in human plasma by gas chromatography/mass spectrometry.
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Synthesis of some benzofuran and furocoumarin derivatives for possible biological activity.
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[Pupillometry, a clinical pharmacological model / Relevance and limits (author's transl)].
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Tumor induction in C57BL X C3HF1 mice following single oral administration of diethylamine hydrochloride (DEA . HCl) and sodium nitrite (NaNO2).
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A modified gas-liquid chromatographic assay to monitor plasma mexiletine in a tinnitus study.
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Improved stability of methanolic Wright's stain solution with dual additives.
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Improved stability of methanolic wright's stain with additive reagents.
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[Pharmacological study on treptilamine in man/study on tolerability (author's transl)].
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[Synthesis of radioactively labelled reproterol hydrochloride (author's transl)].
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Synthesis of the antileukemic compound N,N(11)-[5-[bis(2-chloroethyl)amino]-1, 3-phenylene]bisurea.
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Microbial oxidation of amines. Partial purification of a trimethylamine mono-oxygenase from Pseudomonas aminovorans and its role in growth on trimethylamine.
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Effects of chloroform, diethyl ether and a propiophenone derivative, 3-dimethylamino-2-methyl-2-phenoxypropiophenone hydrochloride, upon cyclic 3',5'-nucleotide phosphodiesterase.
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[Effect of 2 butoxy-3 aminobenzoate hydrochloride of diethyl aminoethyl on 2 types of neural conduction].
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A pharmacological study of n,n-diethyl-[5-(2,4-dichlorophenyl)-4-thiapentyl] amine hydrochloride.
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Distribution studies in mice following the intravenous injection of diethyl beta-iodoethyl amine hydrochloride prepared with radioactive iodine.